Modified soluble fgf receptor fe fusions with improved biological activity.
PK140903AUndetermined Publication Date: 2010-09-20CENTELION SAS
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Patent Information
- Application Number
- PK200701307
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Publication Date
- 2010-09-20
Abstract
The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC / CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules.
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