Polysubstituted 2-aryl-6-phenyl-imidazo[1,2-a]pyridine compound
PK140995AUndetermined Publication Date: 2010-10-27SANOFI AVENTIS SA
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Patent Information
- Application Number
- PK200900252
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Publication Date
- 2010-10-27
Abstract
Compound of formula (I): in which: R1 represents: a phenyl group or a naphthyl group, optionally substituted by one or more atoms or groups; X represents from 1 to 4 substituents, identical to or different from one another, chosen from halogen, (C1-C10)alkyl, halo(C1-C10)alkyl, (C1-¬C10)alkoxy, NRaRb, cyano, nitro, it being possible for the (C1-C10)alkyl to be optionally substituted by halogen or an NRaRb or hydroxyl group; R2 and R3 represent, independently of one another, a hydrogen atom or a (C1-C10)a1ky1 group, this group being optionally substituted by an Rf group, or an aryl group, the aryl being optionally substituted by one or more substituents chosen from a halogen or a (C1C10)alkyl, halo(C1-C10)alkyl, (C1C10)alkoxy, halo(C1-C10)alkoxy, NRaRb, hydroxyl, nitro or cyano group; R2 and X can together form, with the carbon atoms which carry them, a carbon ring of 5 to 7 carbon atoms; R4 represents a hydrogen atom, a (C1-C10)alkyl group, optionally substituted by an Rf group, or an optionally substituted aryl group. Pharmaceutical compositon comprising thereof and process of synthesis.
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