A cytosolic Phospholipase A2 inhibitor compound for use in therapy
PK141114AUndetermined Publication Date: 2011-02-19WYETH LLC
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Patent Information
- Application Number
- PK200600554
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Publication Date
- 2011-02-19
Abstract
This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A2 enzymes (cPLA2), more particularly including inhibitors of cytosolic phospholipase A2 alpha enzymes (cPLA2α). In some embodiments, the inhibitors have the Formula I: wherein the constituent variables are as defined herein.
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