A non-mucoadhasive orally disintegrating film

Abstract

The invention relates to a non-mucoadhesive orally disintegrating film dosage form for delivering active pharmaceutical agents, especially for donezepil and odansetron. In particular, the film dosage form comprises a defined amount of an active pharmaceutical agent, or a pharmaceutically acceptable salt thereof, a hydrophilic binder and a water-soluble diluent, wherein said film is formulated for delivery of said active agent through the gastrointestinal tract when applied to the tongue. In addition, method of formulating the dosage forms to retard absorption through the oral mucosa.