A Method for the preparation of a solvate of metrozineod for the preparation of a solvate of metrozine

Abstract

A method for the preparation of a compound of formula (I)wherein r is 0 and s is 2; and L is methanol, ethanol, propanol, isopropanol, butanol, isobutanol, t-butanol, cyclohexanol, tetrahydrofurfuryl alcohol, ethylene glycol, glycerol, methyl acetate, ethyl acetate, ethyl lactate, butyrolactone, ethylene carbonate, propylene carbonate, acetonitrile, dimethyl sulphoxide, dimethylformamide, dimethylacetamide, N-methyl-2pyrrolidone, N-octy1-2-pyrrolidone, N-decy1-2pyrrolidone, acetone, butanone, methyl isobutyl ketone, methylpropyl ketone, acetophenone, cyclohexanone, methylene chloride, trichloromethane, trichloroethane, tetrahyd rofu ran, diethylether, 1, 2-dimethoxyethane, dioxane, methyl-tert.- butylether, ethanolamine, pyridine, chlorobenzene, toluene, xylene or tetramethylurea; with the proviso that r and s are not simultaneously 0; in each case in free form or in salt form, and its tautomers, in each case in free form or in salt form; pesticides whose active ingredient is selected from the said compounds and its tautomers; and a method for the preparation of its solvates and where appropriate its salts, and a method for the preparation of these compositions, are described.