Pharmaceutical formulation -514
PK200900905A0Active Publication Date: 2009-11-18KUDOS PHARM LIMETED
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Patent Information
- Application Number
- PK200900905
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2009-10-05
- Publication Date
- 2009-11-18
Abstract
The present invention relates to a pharmaceutical formulation comprising the drug 4-[3-(4cyclopropanecarbonyl-piperazine-1-carbonyl)-4fluoro-benzyl]-2H-phthalazin-1-one in a solid dispersion with a matrix polymer that exhibits low hygroscopicity and high softening temperature, such as copovidone. The invention also relates to a daily pharmaceutical dose of the drug provided by such a formulation. In addition, the invention relates to the use of a matrix polymer that exhibits low hygroscopicity and high softening temperature in solid dispersion with 4-[3-(4cyclopropanecarbonyl-piperazine- 1-carbonyl)-4fluoro-benzyl]-2H-phthalazin-1-one for increasing the bioavailability of the drug
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