C-met therapeutic antibodies
PK200901028A0Undetermined Publication Date: 2009-12-18ELI LILLY & CO
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Patent Information
- Application Number
- PK200901028
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2009-11-23
- Publication Date
- 2009-12-18
Abstract
Provided herein is a monoclonal antibody, antigen-binding fragment thereof, and combinations of the foregoing, that binds to, and inhibits the activity of, c-Met, and induces hepatocyte-growth factor-independent internalization of cell surface human c- Met. The monoclonal antibody or antigen-binding fragment thereof is effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by c- Met.
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