Derivatives of 2h pyridazin-3-ones, their preparation and their application in human therapy.

Abstract

The present invention concerns compound of general formula (I) characterized in thatwherein, in particular: -R1 represents one or more groups such as: trifluoromethyl, halogen such as F, Cl, -when n=m=1, W represents CH then Y represents oxygen, -U represents: • either -(C=O)CH2NH- and is branched at position 4 of pyridazinone, then R2 represents H, • or -(C=O)NH- and U is branched at positions (4), (5) or (6) of pyridazinone, then R2 represents H, - R3 represents a hydrogen or methyl and acids and the different isomers, and their mixtures in any proportion.