Methylpyrrolopyrimidinecarboxami des

PK201000733A0Undetermined Publication Date: 2010-09-23TAKEDA GMBH
0 Cites 0 Cited by

Patent Information

Application Number
PK201000733
Authority / Receiving Office
PK · PK
Patent Type
Applications
Current Assignee / Owner
Filing Date
2010-08-23
Publication Date
2010-09-23
Patent Text Reader

Abstract

The present invention relates to compound of formula (I) wherein R1 is -CH2-3-6C-cycloalkyl or 1-4C-alkyl which is optionally substituted by R11, R2 is hydrogen or 1 -4C-alkyl R21 is hydrogen or fluoro, R22 is hydrogen, halogen, 1 -4C-alkyl, 1 -4C-alkoxy, hydroxy, 1-4C-fluoroalkoxy, - C(O)-I -4C- alkyl or 1-4C-fluoroalkyl, or R21 and R22 combine to form a group -0-CH2-O-, R23 is hydrogen, halogen, 1-4C-alkyl, 1 -4C-alkoxy, hydroxy or 1 -4C-fluoroaikoxy, or R22 and R23 combine to form a group -0-CH2-O-, R24 is hydrogen, Y is -(CH2)n-, R3 is a 4- to 7-membered saturated heterocyclic ring containing one nitrogen atom and optionally one oxygen atom, said heterocyclic ring being optionally substituted by R4 and / or by one or two substituents R5, or a 3-6C-cycloalkyl group substituted by R6 and optionally substituted by R61, The stereoisomer of the compound is effective inhibitor of the type 5 phosphodiesterase. The invention relates to methylpyrrolopyrimidinecarboxamide compound, process for its preparation, pharmaceutical composition comprising said compound, for use in the treatment or prophylaxis of diseases.
Need to check novelty before this filing date? Find Prior Art