Spiro-oxindole mdm2 antagonists
PK201000958A0Undetermined Publication Date: 2010-12-01THE RGT UNIV OF MICHIGAN
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Patent Information
- Application Number
- PK201000958
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2010-11-11
- Publication Date
- 2010-12-01
Abstract
Provided herein is a compound of Formula I wherein R1a, R1b, R1c and R1d, R2, R3, R4, X and Y have meaning as defined in the specification. The compound and composition provided herein relate to spiro-oxindoles which function as antagonist of the interaction between p53 and MDM2, for use in the treatment of cancer and other diseases.
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