Oxyntomodulin peptide analogue
PK201001023A0Active Publication Date: 2010-12-27ELI LILLY & CO
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Patent Information
- Application Number
- PK201001023
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2010-12-09
- Publication Date
- 2010-12-27
Abstract
The present invention provides an Oxyntomodulin peptide analogue comprising the amino acid sequence: His-(Aib)-Gln-Gly-Thr-Phe-Thr-5 Ser-Asp-TyrSer-Lys-Tyr-Leu-Asp-Ser-Lys-Lys-Ala-Gln-GluPhe-Val-Gln-Trp-Leu-Leu-Asn-(Aib)-Gly-ArgAsn-Arg-Asn-Asn-Ile-Ala-Xaa38-Xaa39 (SEQ ID NO:5) wherein Xaa38 is Cys, Cys-PEG, or is absent; Xaa 39 is Cys, Cys-PEG, or is absent; and wherein the C-terminal amino acid is optinally amidated. The oxyntomodulin peptide analogue may be useful in the treatment of diabetes and / or obesity.
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