Use of the association of a sinus node if current inhibitor and an angiotensin-converting enzyme inhibitor in the treatment of heart failure

Abstract

Pharmaceutical composition comprising a combination of a selective and specific sinus node If current inhibitor, more especially ivabradine or N-{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1 ,3,5-trien-7yl]methyl}-3-(7,8-dimethoxy-1,2,4,5-tetrahydro3H-3-benzazepin-3-yl)-N-methyl-3-oxo- 1propanamine, and an agent that inhibits angiotensin-converting enzyme in obtaining medicaments intended for the treatment of heart failure, more especially heart failure having preserved systolic function. Also disclosed is a pharmaceutical composition comprising said composition.