12β,17α-Dihydroxy-pregna-1,4-diene-3,20-dione and method for producing 12β,17α-dihydroxy-pregna-1,4-diene-3,20-dione
PL250159B1Active Publication Date: 2026-08-31UNIV PRZYRODNICZY WE WROCAWIU +1
Patent Information
- Application Number
- PL2023444652
- Authority / Receiving Office
- PL · PL
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2023-04-27
- Publication Date
- 2026-08-31
- Estimated Expiration
- 2043-04-27
Abstract
The subject of the application is 12β,17α-Dihydroxy-pregn-1,4-diene-3,20-dione of formula 2 and a method for producing 12β,17α-dihydroxy-pregn-1,4-diene-3,20-dione characterized in that the strain Isaria fumosorosea KCh J2 is introduced into a medium suitable for filamentous fungi, then after at least 72 hours a substrate, which is pregn-1,4-diene-3,20-dione of formula 1, dissolved in an organic solvent miscible with water, is introduced into the culture, the transformation is carried out at a temperature of 20 to 30 degrees Celsius, with continuous shaking, for at least 24 hours, after which the product is extracted with an organic solvent immiscible with water and purified chromatographically.
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Citation Information
Patent Citations
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