Method for treating chronic periodontitis in experiment with laboratory rats

Topical application of adenosine triphosphate disodium salt addresses the limitations of existing treatments by effectively reducing inflammation and restoring periodontal structures in periodontitis, achieving a normal histological structure and eliminating residual signs.

RU2865262C1Active Publication Date: 2026-07-01FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO OBRAZOVANIYA KAZANSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIV MINISTSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERATSII
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Patent Information

Application Number
RU2025133480
Authority / Receiving Office
RU · RU
Patent Type
Patents
Current Assignee / Owner
Filing Date
2025-12-01
Publication Date
2026-07-01
Estimated Expiration
2045-12-01

AI Technical Summary

Technical Problem

Existing treatments for chronic inflammatory periodontal diseases, such as periodontitis, face challenges including diffusion of drugs beyond the lesion site, lack of local effect, mechanical strength, unpleasant odor, allergic reactions, contraindications due to metal structures, and insufficient tissue restoration effects.

Method used

The use of an aqueous solution of adenosine triphosphate disodium salt (ATP) for topical application in treating periodontitis, combined with scaling, curettage, and irrigation, to address the etiopathogenesis of the disease.

Benefits of technology

Reduces signs of chronic inflammation, restores tooth-gingival attachment, and achieves a normal histological structure of the periodontium without residual inflammation.

✦ Generated by Eureka AI based on patent content.

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Abstract

FIELD: dentistry.SUBSTANCE: laboratory rats undergo dental calculus removal, closed curettage, and antiseptic treatment of periodontal pockets using the drug. In this case, an aqueous solution of adenosine triphosphate adisodium salt with a concentration of 25% is used as a drug at intervals of 7 days from the start of treatment.EFFECT: method allows to reduce and eliminate signs of chronic inflammation: swelling, bleeding, hyperemia, and restore gingival attachment.1 cl, 2 dwg, 1 ex
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Citation Information

Patent Citations

  • Method for treating parodontitis

    RU2214217C1

  • Method for treating periodontitis using a mix of soft and hard particles of elite seeds of crambe of sanmo variety and sanmo phytoconcentrate

    RU2785008C1