A serum formula containing marigold extract and a specific manufacturing process.

Abstract

OCR 10KL (13 / 03 / 2569) A serum formula containing marigold extract. Polysorbate 20, propylene glycol, polyethylene glycol. 400 (polyethylene glycol 400), carbomer 934, triethanolamine (triethanolamine) ethanol methyl paraben propyl paraben (propyl paraben) sorbitan monooleate glyceryl monostearate (glyceryl monostearate) petrolatum isopropyl myristate The product is made using myristate and distilled water, and involves separating the parts of fresh marigold flowers. The yellow flower petals are dried, ground into a fine powder, and fermented with 95% ethanol. The mixture is then filtered. Only the liquid portion is taken and concentrated using a rotary evaporator. And then, drying with a freeze-dryer (lyophilizer) will yield an extract from the marigold flowers. Prepare the serum formulation by separating the aqueous and oil phases and heating them in a temperature-controlled bath. (Water bath) Then, slowly pour the oil phase into the water phase and mix in the marigold extract. I got a serum containing marigold extract that has a smooth texture, absorbs well into the skin, and doesn't leave a greasy feeling after application. Sticky, light yellow in color. When applied to the skin, it does not leave a yellow stain. Odorless. Separated into layers. pH value is 6.153 ± 0.03. It exhibits physicochemical stability and chemical stability. Physically, it did not cause any allergic reactions or skin irritation, and the volunteers reported a high level of satisfaction. The most

Claims

OCR 09WP 16 / 03 / 2569 1. The serum formula containing marigold extract has the following ingredients: - Marigold flower extract 0.5-2.5% by weight. - Polysorbate 20: 2.2-2.6% by weight - Propylene glycol 3.5-4.5% by weight. - Polyethylene glycol 400 0.4-0.6% by weight - Carbomer 934 0.3-0.5 percent by weight - Triethanolamine 1.2-1.7 percent by weight. - Ethanol 3.5-4.5 percent by weight. - Methyl paraben 0.2-0.5 percent by weight. - Propyl paraben 0.03-0.06 percent by weight. - Sorbitan monooleate 3.3-3.9 percent by weight. - Glyceryl monostearate 1.5-2.5 percent by weight - Petrolatum 1.5-2.5 percent by weight. - Isopropyl myristate 1.8-2.2 percent by weight - Distilled water: Adjust the volume to reach 100% by weight.

2. The process for manufacturing a serum containing marigold extract, as per claim 1, which includes: The following steps should be followed. Step 1: Preparing the marigold flower extract. A. Wash fresh marigold flowers grown in organic farms free from chemicals and pesticides with water. clean B. Separate the yellow petals and dry them in a hot air oven at 40-45 degrees Celsius. After 24 hours, the flower petals will be dry. C. Grind the dried flower petals into a fine powder using a herb grinder. d. The dry flower petal powder was fermented with 95% ethanol at a ratio of 1 part flower petal powder to 95% ethanol. Mix 3 parts ethanol for 3 days, stirring every 12 hours. The process involves filtering using cotton wool and cheesecloth, separating only the liquid portion. F. Filter the liquid obtained from step E again through filter paper No. 1 to obtain a clear, brown, crude extract. C. Concentrate the crude extract obtained in step F using a rotary distillation apparatus. evaporator) C. The crude extract from step F is dried using a freeze-dryer (lyophilizer) to obtain the extract. Derived from marigold flowers, it is a dry, brown powder. Step 2: The process of manufacturing a serum containing marigold extract. A. Prepare distilled water. B. Sprinkle carbomer 934 into step A. Stir until the carbomer 934 is well mixed. 934) Disperses in water without clumping together. C. Add triethanolamine to the mixture from step B and stir until a clear gel forms. d. Add polysorbate 20 and polyethylene glycol 400. 400) into the gel obtained in step C. D. Heat the mixture from step D in a temperature-controlled water bath until it reaches a temperature of 75-78°C. Celsius degrees. Stir slowly and continuously while heating; the resulting mixture is called the aqueous phase. F. Mix sorbitan monooleate and glyceryl monostearate. monostearate), petrolatum, and isopropyl myristate. B. Heat the mixture from step F in a temperature-controlled water bath until it reaches a temperature of 72-75 degrees Celsius. Celsius, a slow and continuous heating process, results in a mixture called the oil phase. C. Slowly pour the oil phase obtained from step B into the water phase obtained from step E in a thin stream while gently stirring. Continue stirring until the mixture cools down to a temperature of 40-50 degrees Celsius. J. Mix methyl paraben and propyl paraben with propylene glycol. When propylene glycol is stirred, a clear solution is obtained. F. Mix the marigold extract with ethanol and stir until a clear solution is obtained. D. Add the mixtures from steps J and H to the mixture from step C. Stir well for 10-20 minutes. You will get a serum containing marigold extract.