Methods of treating lupus with CD19-CD20 dual car-t cells
TW202626101APending Publication Date: 2026-07-01GENENTECH INC +1
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Patent Information
- Application Number
- TW114144167
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-11-13
- Filing Date
- 2025-11-12
- Publication Date
- 2026-07-01
Abstract
The present disclosure provides methods of treating a systemic lupus erythematosus (e.g. highly active, severe, treatment-refractory systemic lupus erythematosus) by administering a chimeric antigen receptor T cell (CAR-T cell) comprising an anti-CD20 chimeric antigen receptor and an anti-CD19 chimeric antigen receptor. The present disclosure also provides a dose infusion bag comprising a composition comprising CAR-T cells comprising an anti-CD20 chimeric antigen receptor and an anti-CD19 chimeric antigen receptor.
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