Polymorphs of an IRAK-4 degrader

TW202626672APending Publication Date: 2026-07-01SHANGHAI QILU PHARMACEUTICAL RESEARCH & DEVELOPMENT CENTRE LTD

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Patent Information

Application Number: TW114132358
Authority / Receiving Office: TW · TW
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2025-08-19
Filing Date: 2025-08-25
Publication Date: 2026-07-01

Application Information

Patent Timeline

19 Aug 2025

Priority

25 Aug 2025

Application

TW114132358

01 Jul 2026

Publication

TW202626672A

IPC: C07D519/00; A61K31/5386; A61P29/00; A61P37/00

Inventors: 徐西坤; 付強

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Abstract

The present invention discloses polymorphs of an IRAK-4 degrader. Specifically, the present invention provides multiple polymorphs of the IRAK-4 degrader shown in formula (I), salts, pharmaceutical compositions, preparation methods and uses thereof. The polymorphs provided by the present invention can be used to prepare drugs for treating and / or preventing IRAK4-mediated diseases.

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