Multivalent FZD4, wnt co-receptor, and VEGF receptor molecules and uses thereof
TW202626718APending Publication Date: 2026-07-01MERCK SHARP & DOHME CORP +1
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Patent Information
- Application Number
- TW114133842
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-09-06
- Filing Date
- 2025-09-04
- Publication Date
- 2026-07-01
Abstract
Herein are multivalent antibody binding molecules that activate a Wnt / β-catenin signaling pathway comprising a FZD4 receptor binding domain, an LRP5 co-receptor binding domain, and a VEGF binding domain. Also described herein are nucleic acids and vectors encoding said molecules and methods for their use.
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