Use of a PI3kΑ inhibitor in the preparation of a medicament for treating diseases associated with PIK3ca and / or TEK gene mutations
TW202629201APending Publication Date: 2026-07-16SHANGHAI HAIHE PHARMACEUTICAL CO LTD
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Patent Information
- Application Number
- TW114147288
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-12-03
- Filing Date
- 2025-12-03
- Publication Date
- 2026-07-16
Abstract
The present invention provides the use of a PI3Kα inhibitor in the preparation of a medicament for treating diseases associated with mutations in the PIK3CA gene and / or the TEK gene. Specifically, the invention discloses the use of the PI3Kα inhibitor CYH33, or a pharmaceutical composition comprising CYH33, in the preparation of a medicament for preventing, treating, or alleviating PIK3CA-related overgrowth syndromes (PROS) and / or PIK3CA-related vascular malformations (PRVM), and / or vascular malformations associated with TEK gene mutations.
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