Processes for the synthesis of valbenazine
TW202629562APending Publication Date: 2026-07-16NEUROCRINE BIOSCIENCES INC
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Patent Information
- Application Number
- TW114134364
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2019-09-13
- Filing Date
- 2020-09-11
- Publication Date
- 2026-07-16
Abstract
The present application relates to processes for making (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl (S)-2-amino-3-methylbutanoate di(4-methylbenzenesulfonate),which is an inhibitor of vesicular monoamine transporter 2 (VMAT2) useful in the treatment of hyperkinetic movement disorders such as tardive dyskinesia (TD).
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