Culture aids, culture systems, culture aid methods and procedures

The culture aid device and method address the challenge of timing operations in cell culture by analyzing images to estimate future cell density and determine optimal operation times, enhancing process efficiency.

TW202631978APending Publication Date: 2026-08-01NAT UNIV CORP TOKAI NAT HIGHER EDUCATION & RES SYST +1
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Patent Information

Application Number
TW114145193
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-11-20
Filing Date
2025-11-19
Publication Date
2026-08-01

AI Technical Summary

Technical Problem

The challenge in cell culture is determining the optimal timing for operations such as subculturing and medium exchange due to variations in cell growth rates based on cell type and culture conditions, making it difficult to predict when to perform these actions.

Method used

A culture aid device and method that includes an image acquisition unit, past cell density estimation, future cell density estimation, and operation timing determination units to analyze images of a culture medium with scaffold material and cells, estimating future cell density and determining the appropriate operation timing based on these estimates.

Benefits of technology

Enables accurate determination of operation timing in cell culture processes, improving efficiency by accounting for variations in cell growth rates and culture conditions.

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Abstract

The present invention relates to a culture assist device comprising: an image acquisition unit that acquires images of a culture medium containing a scaffold and cells at multiple times; a past cell density estimation unit that estimates the density of the cells on the scaffold based on the images of the culture medium; a future cell density estimation unit that estimates the future cell density on the scaffold based on the multiple times and the cell density on the scaffold in the culture medium estimated by the past cell density estimation unit; and an operation time determination unit that determines the timing for operating the culture medium based on the estimated future cell density on the scaffold.
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