Surface plasma resonance device

The compact surface plasma resonance device with a modular optical element and replaceable detection module addresses the bulkiness and contamination issues of existing methods, enabling portable and instant molecular detection with sensitivity and quantification.

TW202632251AActive Publication Date: 2026-08-01AFFINITY SENSING TECHNOLOGY CO LTD
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Patent Information

Application Number
TW114102376
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Filing Date
2025-01-20
Publication Date
2026-08-01
Estimated Expiration
2045-01-19

AI Technical Summary

Technical Problem

Existing molecular detection methods, such as enzyme immunoassay (ELISA) instruments are bulky and expensive, and rapid screening test strips lack sensitivity and quantification capability, while surface plasma resonance instruments face contamination risks due to liquid samples dripping onto optical and electromechanical components.

Method used

A compact surface plasma resonance device using a modular optical element with integrated mirror assemblies and a replaceable detection module, allowing miniaturization, portability, and instant result generation, while preventing contamination by positioning the optical element above the detection platform.

Benefits of technology

The device achieves miniaturization and portability, enables on-site molecular detection, prevents contamination, and allows easy module replacement, providing sensitive and quantitative results for microfluidic samples.

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Abstract

A surface plasma resonance device comprises: a detection platform having a detection area and an optical element attached to the top surface of the detection area, the optical element having an incident light side and an output light side opposite to each other to receive incident light and provide an output light, wherein the bottom surface is substantially parallel to the incident light and the output light; a light source for generating the incident light; and a photodetector for receiving the output light; wherein the optical element has an incident light guiding structure and a reflected light guiding structure, the incident light guiding structure having a first mirror assembly to guide the incident light to an oblique incident path of the detection area, and the reflected light guiding structure having a second mirror assembly to guide a reflected light of the detection area to generate the output light; wherein the detection area has a slot and a detection module pluggable into the slot, the slot having a light-transmitting top surface, and the detection module having, from top to bottom, a prism, a surface plasma excitation layer, and a flow channel detection chip.
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