Systems and methods for the detection of transitions in thermoregulation and for the early detection of changes to health status

Abstract

In some aspects, the disclosed technology generally relates to a system configured for detection of a transition in thermoregulation. In some embodiments, the system may include at least one sensor configured to measure a plurality of heat flux measurements of a subject over time; a processor configured to receive the plurality of heat flux measurements over time, characterize the relationship between heat flux and temperature over time, and detect a transition from a first thermoregulatory control state to a second thermoregulatory control state prior to an onset of fever or infection; and an indicator prompting proposed intervention prior to the onset of fever or infection. The disclosed technology also generally relates, in certain embodiments, to systems for the early detection of fever, particular in sepsis patients, and methods of detecting health anomalies in sepsis patients.

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