Compositions and methods comprising light-and-magnetoresponsive protein domains

Abstract

Provided herein are compositions comprising light-and-magnetoresponsive protein domain, such as engineered light-oxygen-voltage-sensing (LOV) domains, and methods of using the same. The light-and magnetoresponsive proteins domains may be used to form compositions such as fusion proteins comprising heterologous protein components and bioluminescent protein domains with activity that is dependent on the presence of light, e.g., light emitted by a reaction catalyzed by the bioluminescent protein domain, and on the presence of a magnetic field.

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