Multispecific antigen binding proteins for the expansion of γδ t cells and use thereof

TW202635724APending Publication Date: 2026-09-01AVIDICURE IP BV
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Patent Information

Application Number
TW114141106
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2025-09-12
Filing Date
2025-10-23
Publication Date
2026-09-01

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Abstract

receptor (IL15R) agonist. The γδ T cell co-stimulatory agonist cytokine preferably is at least one of a 4-1BB agonist, a CD27 agonist and a GITR agonist. The multispecific antigen binding proteins of the invention induce expansion and activation of γδ T cells. The invention further relates to the use of such multispecific antigen binding proteins in the treatment of cancers, infectious diseases or inflammatory diseases.
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