A purification of RNA by flowthrough chromatography

TW202635879APending Publication Date: 2026-09-01ETHERNA IMMUNOTHERAPIES NV
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Patent Information

Application Number
TW114142438
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-10-31
Filing Date
2025-10-31
Publication Date
2026-09-01

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Abstract

The present invention relates to the field of RNA purification and in particular to the purification of RNA using chromatography. More specifically, the present invention relates to a method of RNA purification using flowthrough column chromatography wherein a mobile phase comprising an RNA sample is applied to a stationary phase thereby being configured to have binding affinity for impurities other than target RNA, and wherein the mobile phase is free of organic solvents. The invention further relates to the use and a device for flowthrough purification of RNA wherein RNA flows through the stationary phase of the column thereby being free from impurities that remain in the stationary phase.
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