Compounds as voltage-gated sodium channel inhibitors and applications thereof
TW202637145APending Publication Date: 2026-09-16GUANGZHOU UNIRISE PHARM CO LTD +3
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Patent Information
- Application Number
- TW114148819
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2025-08-07
- Filing Date
- 2025-12-12
- Publication Date
- 2026-09-16
Abstract
The present application relates to selective inhibitors of the voltage-gated sodium channel Nav1.8 and their use in the preparation of related pharmaceuticals. The drugs are intended for treating diseases responsive to the inhibition of the voltage-gated sodium channel Nav1.8, such as chronic pain, intestinal pain, neuropathic pain, musculoskeletal pain, acute pain, inflammatory pain, cancer pain, idiopathic pain, postoperative pain, visceral pain, multiple sclerosis, Charcot-Marie-Tooth disease, incontinence, pathological cough, or arrhythmia.
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