Interleukin-12p40 variants, PD-1 antigen-binding domains, and uses thereof
TW202637585APending Publication Date: 2026-09-16ZAI LAB (SHANGHAI) CO LTD +1
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Patent Information
- Application Number
- TW114149240
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-12-13
- Filing Date
- 2025-12-15
- Publication Date
- 2026-09-16
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Abstract
The present disclosure relates to novel variants of human IL-12p40 subunit, reduced potency human IL-12 variants and immunocytokines thereof as well as uses of the same plus PD-1 antigen-binding domains and fusion proteins thereof as well as uses of the same.
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