Biomarkers for lung adenocarcinoma (LUAD), and method for treating luad
TW202637844APending Publication Date: 2026-09-16VETERANS GEN HOSPITAL TAIPEI
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Patent Information
- Application Number
- TW114108793
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2025-03-10
- Publication Date
- 2026-09-16
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Abstract
The present invention provides a method for predicting clinical outcomes of a lung cancer patient, such as LUAD, particularly LUAD with low expression of NKX2-1. Also provided includes a use of inhibitor of CXCR2 in manufacturing a medicament for treating lung adenocarcinoma (LUAD). The present invention provides a strategy of treatment to suppress tumorigenesis and improve the survival outcome of LUAD patients with NKX2-1-low malignant tumors through targeting the NKX2-1 / CXC chemokine signaling.
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