Mutlifunctional drug conjugate of gemfibrozil and a mitochondrial uncoupler, and compositions and methods thereof

TW202639501APending Publication Date: 2026-10-01SHENZHEN HIGHTIDE BIOPHARM
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Patent Information

Application Number
TW114146645
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-12-10
Filing Date
2025-11-28
Publication Date
2026-10-01

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Abstract

The invention provides novel multifunctional conjugates of phenol-based mitochondrial uncoupler (e.g., 2,4-dinitrophenol) and gemfibrozil, and derivatives thereof. The invention also provides pharmaceutical compositions comprising a compound of the invention and methods thereof for treating various diseases and disorders associated with or related to mitochondria or mitochondrial dysfunctions (e.g., neurodegenerative, metabolic and inflammatory diseases and disorders).
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