Crystalline form of free base of imidazo[1,2-a]pyridine compound and preparation method therefor

Abstract

The present invention relates to a crystalline form of an imidazo[1,2-a]pyridine compound, and more specifically, to a monohydrate crystalline form, crystalline form A, and crystalline form B of azetidin-1-yl{8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridin-6-yl}methanone, which serves as an active pharmaceutical ingredient and as an intermediate of a final acid addition salt compound, and to a method for preparing the same. The monohydrate crystalline form, crystalline form A, and crystalline form B of the compound of Chemical Formula I according to the present invention have excellent stability under high-humidity or high-temperature conditions, and can be advantageously used in the formulation of pharmaceutical products.

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