Antibodies that bind to post-translationally modified c9orf72 arginine-rich dipeptide repeat proteins and uses thereof

TW202639587APending Publication Date: 2026-10-01ALS THERAPY DEV INST
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Patent Information

Application Number
TW114151765
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-12-30
Filing Date
2025-12-29
Publication Date
2026-10-01

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Abstract

Isolated monoclonal antibodies that bind to methylated dipeptide repeat proteins (DRPs), e.g., ADMe-GR and SDMe-GR, and related antibody-based compositions and molecules are disclosed. Also disclosed are diagnostic and therapeutic methods for using the antibodies.
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