5'-phosphate modified nucleoside, and preparation method and use thereof

TW202639856APending Publication Date: 2026-10-01BEIJING YUEKANGKECHUANG PHARM TECH CO LTD +1
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Patent Information

Application Number
TW115103258
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2025-01-27
Filing Date
2026-01-27
Publication Date
2026-10-01

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Abstract

The present invention relates to the field of biomedicine and specifically provides 5'-phosphate-modified nucleoside, and preparation method and uses thereof. The present invention provides a modified nucleoside compound having the structure shown in formula (I), or a pharmaceutically acceptable salt or stereoisomer of a compound having the structure shown in formula (I). Oligonucleotides containing the modified nucleoside compound provided by the present invention exhibit significantly enhanced therapeutic efficacy.
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