Methimazole powder or granules and their preparation methods

Abstract

This invention relates to a methimazole powder or granule and its preparation method. By combining solid dispersion technology with a two-stage pulverization process involving micronization modification, a highly dispersed drug powder is prepared to increase the specific surface area of ​​the drug, enhance its dissolution rate, and improve its absorption rate, thereby increasing bioavailability. Other sweeteners are also added to the formulation, resulting in a methimazole powder or granule that completely masks the bitterness and odor of the drug and can be taken directly without water.

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