Small interfering RNA for the modification of hfe2 expression
TW202641570APending Publication Date: 2026-10-16BRII BIOSCIENCES INC
View PDF 0 Cites 0 Cited by
Patent Information
- Application Number
- TW114150852
- Authority / Receiving Office
- TW · TW
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-12-24
- Filing Date
- 2025-12-23
- Publication Date
- 2026-10-16
Smart Images
Figure TWG2TA001080796_001 
Figure TWG2TA001080796_002 
Figure TWG2TA001080796_003
Abstract
This application provides siRNAs that target and reduce the manifestations of hemochromatosis type 2 (HFE2), compositions and methods for using such siRNAs to reduce serum hepcidin concentrations and treat inflammatory anemia, iron-limiting anemia and / or anemia-related disorders. Aspects of the application provide siRNAs that target and reduce the expression of hemochromatosis type 2 (HFE2), compositions and methods of using the same to reduce serum hepcidin concentration and treat anemias of inflammation, iron-restricted anemias and / or conditions associated with anemia.
Need to check novelty before this filing date? Find Prior Art