Anti-ALPP and / or alppl2 antibody and use thereof

TW202641868APending Publication Date: 2026-10-16BEIJING TIDE PHARMACEUTICAL CO LTD
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Patent Information

Application Number
TW115100342
Authority / Receiving Office
TW · TW
Patent Type
Applications
Current Assignee / Owner
Priority Date
2025-01-07
Filing Date
2026-01-05
Publication Date
2026-10-16

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Abstract

The present invention relates to an anti-ALPP and / or ALPPL2 antibody and use thereof. The invention provides monoclonal antibodies against ALPP and / or ALPPL2, particularly high-affinity chimeric antibodies and humanized monoclonal antibodies against ALPP and / or ALPPL2. The invention also provides functional monoclonal antibodies that cross-react with human and cynomolgus monkey ALPP / ALPPL2 but do not bind to ALPI or ALPL. Furthermore, the invention provides amino acid sequences, expression vectors, and host cells for the antibodies of the present invention.
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