Betel nut flavored product

Abstract

This invention provides a areca-flavored product containing arecoline salt. By using arecoline salt in the product, the user can ingest arecoline when inhaling it, producing an effect similar to chewing areca nut, but with lower irritation.

Description

Technical Field

[0001] The present invention belongs to the technical field of chemical synthesis and relates to a product with a betel nut flavor. Prior Art

[0002] Arecoline, with the chemical name "methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate", is an oily liquid and has a cholinomimetic effect. Arecoline is a compound with great application value, and its preparation method and application have always attracted people's attention.

[0003] However, arecoline has unstable properties, and there are no commercial products currently available. It is impossible to determine the conversion rate of arecoline, and it is even more impossible to determine whether it can enable smokers to achieve the effect of chewing betel nuts; in addition, the application of arecoline salts in products has not been discovered yet. Summary of the Invention

[0004] The present invention provides a product with a betel nut flavor, and the product contains arecoline salts.

[0005] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a coordinating acid.

[0006] In some embodiments, the coordinating acid of the arecoline salt is selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0007] In some embodiments, the molar ratio of the arecoline to the coordinating acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, and further preferably 0 < n ≤ 2.

[0008] In some embodiments, the article is an aerosol-forming matrix for atomization to generate an inhalable aerosol.

[0009] In some embodiments, the aerosol forming matrix is ​​a liquid phase, which is used to generate an aerosol by atomization using any one of a heated atomizing device, an ultrasonic atomizing device, an air compression atomizing device, or a press-type spraying device.

[0010] In some embodiments, the aerosol generating matrix is ​​a solid phase, configured to generate an inhalable aerosol when heated below its ignition point.

[0011] In some embodiments, the article is a bursting bead used in aerosol-generating articles.

[0012] In some embodiments, the product is chewing gum.

[0013] In some embodiments, the product is a beverage.

[0014] This invention uses arecoline salt in the product, so that users can ingest arecoline when inhaling it, and it produces a similar effect to chewing areca nut, but with lower irritation. Simple Explanation of the Diagram

[0015] none Implementation

[0016] The present invention will be further described in conjunction with the following embodiments.

[0017] Implementation Method 1:

[0018] Embodiment 1 of the present invention provides the use of arecoline salt in the preparation of aerosol forming matrix.

[0019] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a complexing acid.

[0020] In some embodiments, the counteracid of the arecoline salt is selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0021] In some embodiments, the molar ratio of the arecoline to the counteracid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0022] In some embodiments, when preparing the aerosol-forming matrix, based on the total mass of the aerosol-forming matrix, the mass percentage of the arecoline salt is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, more preferably 2% - 10%, more preferably 2% - 5%, more preferably 2% - 4%.

[0023] In some embodiments, when preparing the aerosol-forming matrix, the substances added to the arecoline salt include a solvent.

[0024] In some embodiments, the solvent is selected from at least one of the following: 丙二醇, 1,3-propanediol, glycerol, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol ether, ethanol, water, triethyl citrate, triacetin, caprylic capric triglyceride, isopropyl alcohol, sweet orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, salad oil.

[0025] In some embodiments, the solvent includes glycerol, and the mass percentage of the glycerol is 0 - 90%.

[0026] In some embodiments, the solvent includes propylene glycol, and the mass percentage of the propylene glycol is 9% - 99.8%.

[0027] Note: There is an error in the Chinese text in item . "丙二醇" should be "1,2-propanediol" in the English translation. The corrected English translation for item is: In some embodiments, the solvent is selected from at least one of the following: 1,2-propanediol, 1,3-propanediol, glycerol, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol ether, ethanol, water, triethyl citrate, triacetin, caprylic capric triglyceride, isopropyl alcohol, sweet orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, salad oil.In some embodiments, the substances added to the arecoline salt also include flavoring agents.

[0028] In some embodiments, the flavoring agent is selected from at least one of the following: nerol, trans-2-hexen-1-ol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, β-phenylethanol, linalool oxide, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, n-valeric acid, n-hexanoic acid, edible acetic acid, n-octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isoamyl alcohol. Acids, Isoamyl acetate, Amyl formate, Geraniol formate, Butyl formate, Benzyl formate, Leaf formate, Glyceryl decyl lactone, D-nonyl lactone, Glyceryl octyl lactone, Glyceryl heptanyl lactone, Glyceryl undecanolyl lactone, D-dodecyl lactone, Benzaldehyde, Strawberry aldehyde, Cinnamaldehyde, Furfural, Citral, Acetaldehyde, 3-Methylthiopropional, Natural 3-Mercapto-2-methylpentanal, Isobutanal, Trans-2-octenal, Trans-2-nonenal, Trans-2-decenal, Trans, Trans-2,4-heptadienal, 2,5-Dimethylpyrazine, 2-acetylglucuron, 2-ethyl 2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Tufylenone No. 2 (Firmfine), Butylene dione, Methylionone, Acetaminophen (Acetylmethyl orthogenol), Acetaminophen (Acetylmethyl orthogenol), Methylheptenone, Vanillin, Ethyl vanillin, Dihydrocoumarin, Raspberry ketone, Anethole, Methyl cedarwood ether, Methyl-2-methyl-3-furanyl disulfide, Wintergreen oil, Clove bud oil, Tenfold sweet orange oil Rosewood oil, geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, concentrated vanillin, torreya extract, Peruvian extract, oak extract, supercritical extraction of espresso (water-soluble), cocoa extract, coffee tincture, angelica tincture, vanilla extract, herb extract, labdanum extract, iris oil or extract, jasmine extract, tree moss extract (amber scent), tamarind extract, zimbabwean tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco oil A, flue-cured tobacco odor extract, sun-dried tobacco odor extract.

[0029] It should be noted that fragrances are not limited to the substances listed above; any fragrance that conforms to FEMA or CAS codes is acceptable.

[0030] In some embodiments, the contents added to the arecoline salt do not contain nicotine and / or nicotine salts.

[0031] Implementation Method Two:

[0032] Embodiment 2 of the present invention provides an aerosol forming matrix, the aerosol forming matrix comprising: arecoline salt; solvent; and optionally, flavoring agent.

[0033] Preferably, based on the total mass of the aerosol-forming matrix, the mass percentage of arecoline salt is 0.2% to 15%, more preferably 1% to 15%, further preferably 2% to 15%, further preferably 2% to 12%, further preferably 2% to 10%, further preferably 2% to 8%, further preferably 2% to 5%, further preferably 2% to 4%, further preferably 2% to 3%, and more preferably 3% to 4%.

[0034] Preferably, the complex acid of the arecoline salt includes at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, stearic acid, arachidic acid, benzoic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, aspartamine, glutamine, threonine, aspartic acid, glutamine, lysine, arginine, and histamine.

[0035] Preferably, the arecoline salt is arecoline hydrobromide and / or arecoline benzoate.

[0036] Preferably, the arecoline salt is obtained by neutralizing arecoline extracted from areca nut with the complex acid.

[0037] Preferably, the arecoline salt is arecoline hydrobromide or arecoline benzoate, and the preparation method is as follows: arecoline is extracted from areca fruit using ethyl acetate as the extractant, the pH value of the extract is adjusted to 7.5~8.5, the ethyl acetate layer is taken, and arecoline salt crystals are generated by adding hydrobromic acid or benzoic acid. The arecoline salt crystals are then recrystallized to obtain arecoline hydrobromide or arecoline benzoate.

[0038] Preferably, the solvent includes at least one of the following: propylene glycol, glycerin, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, palm oil, peanut oil, corn oil, and salad oil.

[0039] Preferably, the solvent includes glycerol, and the mass percentage of glycerol in the aerosol forming matrix is ​​0-90%, preferably 0%-80%, more preferably 0%-70%, more preferably 0%-60%, more preferably 10%-60%, more preferably 20%-60%, more preferably 30%-60%, more preferably 40%-60%, and even more preferably 50%-60%.

[0040] Preferably, the solvent includes propylene glycol, and the mass percentage of propylene glycol in the aerosol forming matrix is ​​9% to 99.8%, preferably 9% to 90%, more preferably 9% to 80%, more preferably 9% to 70%, more preferably 9% to 60%, more preferably 9% to 50%, more preferably 20% to 50%, more preferably 30% to 50%, and even more preferably 35% to 45%.

[0041] Preferably, the aerosol forming matrix includes a flavoring agent selected from at least one of the following: nerol, trans-2-hexen-1-ol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, β-phenylethanol, linalool oxide, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, n-valeric acid, n-hexanoic acid, edible acetic acid, n-octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3- Methylvalerate, isovaleric acid, isoamyl acetate, amyl formate, geranyl formate, butyl formate, benzyl formate, leaf formate, denolide, nonanolide, octyl lactone, heptanyl lactone, undecyl lactone, dodecalide, benzaldehyde, strawberry aldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropional, natural 3-mercapto-2-methylvaleral, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans, trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylglucuronide Uranium, 2-Ethyl-3(5 or 6)-Dimethylpyrazine, 2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Tufylenone No. 2 (Firmcare), Butylene dione, Methyl ionone, Acetaminophen (Acetylmethyl orthogenol), Acetaminophen (Acetylmethyl orthogenol), Methylheptenone, Vanillin, Ethyl vanillin, Dihydrocoumarin, Raspberry ketone, Anethole, Methyl cedarwood ether, Methyl-2-methyl-3-furanyl disulfide, Wintergreen oil, Clove bud oil, 10x Sweet orange oil, rosewood oil, geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, concentrated vanillin, Tururu extract, Peruvian extract, oak extract, supercritical extraction of espresso (water-soluble), cocoa extract, coffee tincture, Angelica pubescens tincture, vanilla extract, herb extract, labdanum extract, iris oil or extract, jasmine extract, tree moss extract (amber scent), tamarind extract, Zimbabwean tobacco extract, tobacco essential oil, Burley tobacco extract, flue-cured tobacco oil A, flue-cured tobacco odor extract, sun-dried tobacco odor extract.

[0042] It should be noted that fragrances are not limited to the substances listed above; any fragrance that conforms to FEMA or CAS codes is acceptable.

[0043] Experimental testing methods:

[0044] Arecoline salt is selected from arecoline hydrobromide. The solvent is a mixture of glycerol and propylene glycol in a 1:1 mass ratio.

[0045] The aerosol was drawn using a smoke extractor according to international standards, and the aerosol atomized from the aerosol forming matrix was collected using a Cambridge filter. The mass of arecoline hydrobromide in the aerosol was measured as m1. The mass of arecoline hydrobromide in the remaining aerosol forming matrix was then measured as m2, and the mass of total arecoline hydrobromide in the aerosol forming matrix was measured as m0. The conversion rate k was calculated as k = m1 / (m0-m2).

[0046] The relevant international standards can be referenced as follows:

[0047] CORESTA RECOMMENDED METHOD N° 81, Afnor standardization XP D90-300-3, International Standard ISO 20768:2018 and PD CEN / TR 17236:2018.

[0048] The parameters for using electronic cigarettes are as follows: Puff Duration 3.0s±0.1s Puff Volume 55mL±0.3mL Puff Frequency 30s±0.5s Number of suctions per group (Puff of Each Group) 20 Group Interval Time 300s±120s Maximum Flow 18.5 mL / s ± 0.1 mL / s Pressure Drop <50hPa Group 5 Total Number of Puffs 100 Total Duration of Vaporization 300s

[0049] Suction experience test:

[0050] After aerosol forming matrix is ​​atomized, the inhalation experience can be evaluated from two aspects: first, the user's satisfaction after inhaling arecoline salt; second, the discomfort experienced after inhaling excessive arecoline salt. Through evaluation by multiple users and considering both aspects, different aerosol forming matrices were scored from 0 to 5 points to obtain examples with better inhalation experiences.

[0051] Experimental test results: Example Arecoline salt content (wt%) k Arecoline salt content in aerosols (wt%) suction experience 1 Arecoline hydrobromide 0.1% 89% 0.09% 0 2 Arecoline hydrobromide 0.2% 87% 0.17% 1 3 Arecoline hydrobromide 1% 79% 0.8% 1 4 Arecoline hydrobromide 2% 77% 1.5% 2 5 Arecoline hydrobromide 3% 75% 2.2% 5 6 Arecoline hydrobromide 4% 68% 2.7% 4 7 Arecoline hydrobromide 5% 62% 3.1% 3 8 Arecoline hydrobromide 10% 56% 5.6% 2 9 Arecoline hydrobromide 15% 56% 8.4% 1 10 Arecoline hydrobromide 20% 45% 9.0% 0

[0052] Suction experience test:

[0053] The experimental results show that the conversion rate decreases with increasing arecoline hydrobromide content in the aerosol-forming matrix. Even when the arecoline hydrobromide content in the aerosol-forming matrix reaches 15%, the conversion rate remains above 50%. Furthermore, different arecoline hydrobromide contents in the aerosol-forming matrix result in varying arecoline salt content and different inhalation experiences. When the arecoline salt content in the aerosol-forming matrix is ​​below 0.2%, inhalers do not experience the satisfaction derived from arecoline intake; as the content increases, the satisfaction improves; above 5%, discomfort from arecoline salt intake begins to appear, and under experimental conditions, this discomfort gradually increases with increasing content; above 15%, the discomfort becomes unacceptable.

[0054] Implementation Method 3:

[0055] Embodiment 3 of the present invention provides an aerosol generation system, including an atomizing device and the aerosol forming matrix described in Embodiment 2; the atomizing device is configured to atomize the aerosol forming matrix to form an aerosol.

[0056] In some implementations, the atomizing device is a heated atomizing device.

[0057] In some implementations, the atomizing device is an ultrasonic atomizing device.

[0058] In some embodiments, the aerosol forming matrix includes arecoline salt, glycerol, and propylene glycol.

[0059] In some embodiments, the oscillation frequency of the ultrasonic atomization device is greater than 1 MHz.

[0060] In some embodiments, the atomization device is an air compression atomization device or a press-type spray device.

[0061] In some embodiments, the aerosol-forming matrix includes arecoline salt, ethanol, and water.

[0062] Embodiment 4:

[0063] Embodiment 4 of the present invention provides a use of arecoline salt in the manufacture of aerosol generating products.

[0064] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a coordinating acid.

[0065] In some embodiments, the coordinating acid of the arecoline salt is selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0066] In some embodiments, the molar ratio of the arecoline to the coordinating acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, further preferably 0 < n ≤ 8, further preferably 0 < n ≤ 5, further preferably 0 < n ≤ 3, further preferably 0 < n ≤ 2.

[0067] In some embodiments, when manufacturing the aerosol generating product, based on the total mass of the raw materials of the aerosol generating product, the mass percentage of the arecoline salt is 0.2% - 15%, preferably 1% - 15%, further preferably 2% - 15%, further preferably 2% - 10%, further preferably 2% - %, further preferably 2% - 4%, more preferably 3% - 4%.

[0068] In some embodiments, when manufacturing the aerosol-generating article, the substances added to the arecoline salt include: atomizing agents, adhesives, and plant fibers.

[0069] In some embodiments, when manufacturing the aerosol generating article, the mass percentage of the atomizing agent is 5% to 30% based on the total mass of the raw materials of the aerosol generating article, preferably 10% to 30%, more preferably 10% to 25%, and even more preferably 15% to 25%.

[0070] In some embodiments, the atomizing agent is selected from at least one of the following: 1,2-propanediol, 1,3-propanediol, glycerol, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, sweet orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, and salad oil.

[0071] In some embodiments, when manufacturing the aerosol-generating article, the adhesive has a mass percentage of 1% to 20% based on the total mass of the raw materials of the aerosol-generating article, preferably 1% to 15%, more preferably 1% to 10%, more preferably 3% to 10%, and more preferably 5% to 10%.

[0072] In some embodiments, the adhesive is selected from at least one of the following: carboxymethyl cellulose, hydroxypropyl methyl cellulose, polyvinyl alcohol, rosin, xanthan gum, gum arabic, guar gum, chitosan, pectin, locust bean gum, starch, sodium alginate, and shellac.

[0073] In some embodiments, when manufacturing the aerosol-generating article, the plant fiber mass percentage is 40% to 80% based on the total mass of the raw materials for the aerosol-generating article, preferably 40% to 70%, more preferably 50% to 70%, more preferably 50% to 65%, and even more preferably 50% to 60%.

[0074] In some embodiments, the plant fiber is selected from at least one of the following: areca nut fiber, wood pulp fiber, hemp pulp fiber, cotton pulp fiber, bagasse pulp fiber, bamboo pulp fiber, and coconut pulp fiber.

[0075] In some embodiments, the substances added to the arecoline salt also include flavoring agents.

[0076] In some embodiments, the flavoring agent is selected from at least one of the following: nerol, trans-2-hexen-1-ol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, β-phenylethanol, linalool oxide, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, n-valeric acid, n-hexanoic acid, edible acetic acid, n-octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isoamyl alcohol. Acids, Isoamyl acetate, Amyl formate, Geraniol formate, Butyl formate, Benzyl formate, Leaf formate, Glyceryl decyl lactone, D-nonyl lactone, Glyceryl octyl lactone, Glyceryl heptanyl lactone, Glyceryl undecanolyl lactone, D-dodecyl lactone, Benzaldehyde, Strawberry aldehyde, Cinnamaldehyde, Furfural, Citral, Acetaldehyde, 3-Methylthiopropional, Natural 3-Mercapto-2-methylpentanal, Isobutanal, Trans-2-octenal, Trans-2-nonenal, Trans-2-decenal, Trans, Trans-2,4-heptadienal, 2,5-Dimethylpyrazine, 2-acetylglucuron, 2-ethyl 2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Tufylenone No. 2 (Firmfine), Butylene dione, Methylionone, Acetaminophen (Acetylmethyl orthogenol), Acetaminophen (Acetylmethyl orthogenol), Methylheptenone, Vanillin, Ethyl vanillin, Dihydrocoumarin, Raspberry ketone, Anethole, Methyl cedarwood ether, Methyl-2-methyl-3-furanyl disulfide, Wintergreen oil, Clove bud oil, Tenfold sweet orange oil Rosewood oil, geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, concentrated vanillin, torreya extract, Peruvian extract, oak extract, supercritical extraction of espresso (water-soluble), cocoa extract, coffee tincture, angelica tincture, vanilla extract, herb extract, labdanum extract, iris oil or extract, jasmine extract, tree moss extract (amber scent), tamarind extract, zimbabwean tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco oil A, flue-cured tobacco odor extract, sun-dried tobacco odor extract.

[0077] It should be noted that fragrances are not limited to the substances listed above; any fragrance that conforms to FEMA or CAS codes is acceptable.

[0078] In some embodiments, the substance added to the arecoline salt does not contain tobacco components.

[0079] In some embodiments, the method for manufacturing the aerosol-generated article includes one of the following: papermaking, dry papermaking, slurry making, and rolling.

[0080] Embodiment 5:

[0081] Embodiment 5 of the present invention provides an aerosol generating product, the raw materials of which include arecoline salt, atomizing agent, binder and plant fiber.

[0082] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a compatible acid.

[0083] In some embodiments, the compatible acid of the arecoline salt is selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0084] In some embodiments, the molar ratio of the arecoline to the compatible acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0085] In some embodiments, based on the total mass of the raw materials, the mass percentage of the arecoline salt is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, more preferably 2% - 10%, more preferably 2% - 5%, more preferably 2% - 4%, and even more preferably 3% - 4%.

[0086] In some embodiments, based on the total mass of the raw materials, the mass percentage of the atomizing agent is 5% - 30%, preferably 10% - 30%, more preferably 10% - 25%, more preferably 15% - 25%.

[0087] In some embodiments, the atomizing agent is selected from at least one of the following: 1,2-propanediol, 1,3-propanediol, glycerol, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, sweet orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, and salad oil.

[0088] In some embodiments, the adhesive is 1% to 20% by mass of the total raw materials, preferably 1% to 15%, more preferably 1% to 10%, more preferably 3% to 10%, and more preferably 5% to 10%.

[0089] In some embodiments, the adhesive is selected from at least one of the following: carboxymethyl cellulose, hydroxypropyl methyl cellulose, polyvinyl alcohol, rosin, xanthan gum, gum arabic, guar gum, chitosan, pectin, locust bean gum, starch, sodium alginate, and shellac.

[0090] In some embodiments, the plant fiber accounts for 40% to 80% of the total mass of the raw materials, preferably 40% to 70%, more preferably 50% to 70%, more preferably 50% to 65%, and even more preferably 50% to 60%.

[0091] In some embodiments, the plant fiber is selected from at least one of the following: areca nut fiber, wood pulp fiber, hemp pulp fiber, cotton pulp fiber, bagasse pulp fiber, bamboo pulp fiber, and coconut pulp fiber.

[0092] In some embodiments, the raw material also includes a flavoring agent.

[0093] In some embodiments, the flavoring agent is selected from at least one of the following: nerol, trans-2-hexen-1-ol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, β-phenylethanol, linalool oxide, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, n-valeric acid, n-hexanoic acid, edible acetic acid, n-octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isoamyl alcohol. Acids, Isoamyl acetate, Amyl formate, Geraniol formate, Butyl formate, Benzyl formate, Leaf formate, Glyceryl decyl lactone, D-nonyl lactone, Glyceryl octyl lactone, Glyceryl heptanyl lactone, Glyceryl undecanolyl lactone, D-dodecyl lactone, Benzaldehyde, Strawberry aldehyde, Cinnamaldehyde, Furfural, Citral, Acetaldehyde, 3-Methylthiopropional, Natural 3-Mercapto-2-methylpentanal, Isobutanal, Trans-2-octenal, Trans-2-nonenal, Trans-2-decenal, Trans, Trans-2,4-heptadienal, 2,5-Dimethylpyrazine, 2-acetylglucuron, 2-ethyl 2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Tufylenone No. 2 (Firmfine), Butylene dione, Methylionone, Acetaminophen (Acetylmethyl orthogenol), Acetaminophen (Acetylmethyl orthogenol), Methylheptenone, Vanillin, Ethyl vanillin, Dihydrocoumarin, Raspberry ketone, Anethole, Methyl cedarwood ether, Methyl-2-methyl-3-furanyl disulfide, Wintergreen oil, Clove bud oil, Tenfold sweet orange oil Rosewood oil, geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, concentrated vanillin, torreya extract, Peruvian extract, oak extract, supercritical extraction of espresso (water-soluble), cocoa extract, coffee tincture, angelica tincture, vanilla extract, herb extract, labdanum extract, iris oil or extract, jasmine extract, tree moss extract (amber scent), tamarind extract, zimbabwean tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco oil A, flue-cured tobacco odor extract, sun-dried tobacco odor extract.

[0094] It should be noted that fragrances are not limited to the substances listed above; any fragrance that conforms to FEMA or CAS codes is acceptable.

[0095] In some implementations, the raw material does not contain tobacco components.

[0096] Example 1:

[0097] Prepare a heat-not-burn cigarette according to the following steps:

[0098] Step 1: Prepare a thin film substrate.

[0099] Select solid residue from areca nut extract, soak it in water at a temperature of 60-80℃ for 0.5-2 hours, filter it, and then pulp the filtered solid to obtain a slurry. Weigh 50-70 parts of the slurry and 3-10 parts of the solid binder by weight, mix them evenly, and send the mixed slurry to a paper machine for forming. Dry it to a moisture content of about 10-15% to obtain a sheet substrate. The solid binder can be one or more of carboxymethyl cellulose, hydroxypropyl methyl cellulose, polyvinyl alcohol, rosin, xanthan gum, gum arabic, guar gum, chitosan, pectin, locust bean gum, starch, sodium alginate, and shellac.

[0100] Step 2: Prepare the coating solution.

[0101] Weigh out 1-50 parts of arecoline salt, 2-20 parts of fragrance, and 40-80 parts of atomizing agent by weight, mix them evenly to obtain a coating liquid; wherein, the atomizing agent is a mixture of glycerin and propylene glycol, and the mixing ratio is 3-5:1.

[0102] Step 3: Coat the film substrate.

[0103] Weigh out 25% to 40% of the weight of the substrate obtained in step 1, and spray the coating solution onto the substrate. Let it stand for 40 to 60 hours under constant temperature and humidity conditions to obtain plant slices containing arecoline salt.

[0104] Step 4: Prepare a heated non-combustible cigarette.

[0105] The plant slices obtained in step 3 are made into cigarette sticks according to the specified size. The cigarette sticks are then connected to the filter to obtain a heated non-combustible cigarette containing arecoline salt.

[0106] The heated non-combustible cigarette prepared by the above method was heated using an aerosol generating device (resistance heating). The surface temperature of the heating element in operation was measured using an infrared thermal imager. The test results are shown in the table below. Aspiration time (temperature) Element 1s (°C) 2s (°C) 3s (°C) Arecoline salt 153.1 228.3 241.1

[0107] It can be seen from the test results that the arecoline salt in the cigarette stick can be atomized and generate inhalable aerosol between 150 °C and 250 °C.

[0108] Smoking and sensory quality evaluation were carried out on the heat-not-burn cigarette stick: The heat-not-burn cigarette stick prepared by the above preparation method can extract arecoline and produce a similar effect to chewing betel nuts, with relatively low irritation.

[0109] Embodiment 6:

[0110] Embodiment 6 of the present invention provides a use of arecoline salt in a liquid composition for preparing a bursting bead; wherein, the bursting bead includes a fragile shell and the liquid composition, and the liquid composition is disposed inside the fragile shell.

[0111] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a coordinating acid.

[0112] In some embodiments, the coordinating acid of the arecoline salt is selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0113] In some embodiments, the molar ratio of the arecoline to the coordinating acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0114] In some embodiments, the arecoline salt is 0.2% to 15% by mass of the total liquid composition, preferably 1% to 15%, more preferably 2% to 15%, more preferably 2% to 10%, more preferably 2% to 5%, more preferably 2% to 4%, and even more preferably 3% to 4%.

[0115] In some embodiments, when preparing the liquid composition, the substance added to the arecoline salt includes an atomizing agent.

[0116] In some embodiments, the atomizing agent is 5% to 30% by mass of the total liquid composition, preferably 10% to 30%, more preferably 10% to 25%, and even more preferably 15% to 25%.

[0117] In some embodiments, the atomizing agent is selected from at least one of the following: 1,2-propanediol, 1,3-propanediol, glycerol, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, sweet orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, and salad oil.

[0118] In some embodiments, the substances added to the arecoline salt also include flavoring agents.

[0119] In some embodiments, the flavoring agent is selected from at least one of the following: nerol, trans-2-hexen-1-ol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, β-phenylethanol, linalool oxide, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, n-valeric acid, n-hexanoic acid, edible acetic acid, n-octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isoamyl alcohol. Acids, Isoamyl acetate, Amyl formate, Geraniol formate, Butyl formate, Benzyl formate, Leaf formate, Glyceryl decyl lactone, D-nonyl lactone, Glyceryl octyl lactone, Glyceryl heptanyl lactone, Glyceryl undecanolyl lactone, D-dodecyl lactone, Benzaldehyde, Strawberry aldehyde, Cinnamaldehyde, Furfural, Citral, Acetaldehyde, 3-Methylthiopropional, Natural 3-Mercapto-2-methylpentanal, Isobutanal, Trans-2-octenal, Trans-2-nonenal, Trans-2-decenal, Trans, Trans-2,4-heptadienal, 2,5-Dimethylpyrazine, 2-acetylglucuron, 2-ethyl 2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Tufylenone No. 2 (Firmfine), Butylene dione, Methylionone, Acetaminophen (Acetylmethyl orthogenol), Acetaminophen (Acetylmethyl orthogenol), Methylheptenone, Vanillin, Ethyl vanillin, Dihydrocoumarin, Raspberry ketone, Anethole, Methyl cedarwood ether, Methyl-2-methyl-3-furanyl disulfide, Wintergreen oil, Clove bud oil, Tenfold sweet orange oil Rosewood oil, geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, concentrated vanillin, torreya extract, Peruvian extract, oak extract, supercritical extraction of espresso (water-soluble), cocoa extract, coffee tincture, angelica tincture, vanilla extract, herb extract, labdanum extract, iris oil or extract, jasmine extract, tree moss extract (amber scent), tamarind extract, zimbabwean tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco oil A, flue-cured tobacco odor extract, sun-dried tobacco odor extract.

[0120] It should be noted that fragrances are not limited to the substances listed above; any fragrance that conforms to FEMA or CAS codes is acceptable.

[0121] In some embodiments, the contents added to the arecoline salt do not contain nicotine and / or nicotine salts.

[0122] In some embodiments, the burst beads are embedded in an aerosol-generating product.

[0123] In some embodiments, the raw materials of the aerosol generating product do not contain tobacco components.

[0124] Embodiment Seven:

[0125] Embodiment Seven of the present invention provides a popping bead, comprising a fragile shell and a liquid composition, the liquid composition being disposed within the fragile shell; wherein the liquid composition comprises arecoline salt and an atomizing agent.

[0126] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a coordinating acid.

[0127] In some embodiments, the coordinating acid of the arecoline salt is selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0128] In some embodiments, the molar ratio of the arecoline to the coordinating acid is n; wherein the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0129] In some embodiments, based on the total mass of the liquid composition, the mass percentage of the arecoline salt is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, more preferably 2% - 10%, more preferably 2% - 5%, more preferably 2% - 4%, and even more preferably 3% - 4%.

[0130] In some embodiments, based on the total mass of the liquid composition, the mass percentage of the atomizing agent is 5% - 30%, preferably 10% - 30%, more preferably 10% - 25%, more preferably 15% - 25%.

[0131] In some embodiments, the atomizing agent is selected from at least one of the following: 1,2-propanediol, 1,3-propanediol, glycerol, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, sweet orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, and salad oil.

[0132] In some embodiments, the liquid composition further includes a fragrance agent.

[0133] In some embodiments, the flavoring agent is selected from at least one of the following: nerol, trans-2-hexen-1-ol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, β-phenylethanol, linalool oxide, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyric acid, malic acid, n-valeric acid, n-hexanoic acid, edible acetic acid, n-octanoic acid, strawberry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isoamyl alcohol. Acids, Isoamyl acetate, Amyl formate, Geraniol formate, Butyl formate, Benzyl formate, Leaf formate, Glyceryl decyl lactone, D-nonyl lactone, Glyceryl octyl lactone, Glyceryl heptanyl lactone, Glyceryl undecanolyl lactone, D-dodecyl lactone, Benzaldehyde, Strawberry aldehyde, Cinnamaldehyde, Furfural, Citral, Acetaldehyde, 3-Methylthiopropional, Natural 3-Mercapto-2-methylpentanal, Isobutanal, Trans-2-octenal, Trans-2-nonenal, Trans-2-decenal, Trans, Trans-2,4-heptadienal, 2,5-Dimethylpyrazine, 2-acetylglucuron, 2-ethyl 2,3,5,6-Tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Tufylenone No. 2 (Firmfine), Butylene dione, Methylionone, Acetaminophen (Acetylmethyl orthogenol), Acetaminophen (Acetylmethyl orthogenol), Methylheptenone, Vanillin, Ethyl vanillin, Dihydrocoumarin, Raspberry ketone, Anethole, Methyl cedarwood ether, Methyl-2-methyl-3-furanyl disulfide, Wintergreen oil, Clove bud oil, Tenfold sweet orange oil Rosewood oil, geranium oil, bitter almond oil, clove basil oil, ethyl vanillin, dihydrocoumarin, raspberry ketone, concentrated vanillin, torreya extract, Peruvian extract, oak extract, supercritical extraction of espresso (water-soluble), cocoa extract, coffee tincture, angelica tincture, vanilla extract, herb extract, labdanum extract, iris oil or extract, jasmine extract, tree moss extract (amber scent), tamarind extract, zimbabwean tobacco extract, tobacco essential oil, burley tobacco extract, flue-cured tobacco oil A, flue-cured tobacco odor extract, sun-dried tobacco odor extract.

[0134] It should be noted that fragrances are not limited to the substances listed above; any fragrance that conforms to FEMA or CAS codes is acceptable.

[0135] In some embodiments, the liquid composition does not contain nicotine and / or nicotine salts.

[0136] Implementation Method Eight:

[0137] Embodiment 8 of the present invention provides an aerosol generating product, including the burst beads described in Embodiment 7.

[0138] In some embodiments, the raw materials for the aerosol-generated articles do not contain tobacco components.

[0139] In this embodiment, aerosol-generating products can be prepared using papermaking, dry papermaking, slurry processing, or roll pressing. Specifically, the raw materials and preparation steps of the aerosol-generating products can be found in the foregoing embodiments.

[0140] The capsule can be inserted into the filter section (not limited to this position) of a heated tobacco product using a filter rod embedding technology (but not limited to this technology). When in use, the smoker can squeeze the capsule to ingest substances such as arecoline.

[0141] It should be noted that, in this embodiment, there are no special restrictions on the composition of the fragile shell and its preparation process, as well as the preparation process of the burst beads; any technology known to those skilled in the art to which this invention pertains can be used.

[0142] Example 1:

[0143] The liquid composition in the popping beads was prepared according to the following formula: 10 wt% arecoline salt, 80 wt% caprylic / capric glyceride, and 10 wt% menthol.

[0144] Preparation method: Weigh the arecoline salt according to the above formula, add caprylic / capric triglyceride and menthol while stirring, and mix well to prepare the product.

[0145] The heat-not-burning cigarette containing the capsule of Example 1 was implanted and compared with the heat-not-burning cigarette without the capsule in terms of smoking and sensory quality evaluation: The heat-not-burning cigarette containing the capsule of Example 1 can ingest arecoline and produce a similar effect to chewing areca nut, with lower irritation.

[0146] Embodiment Nine:

[0147] Embodiment Nine of the present invention provides a use of arecaidine salt in the manufacture of chewing gum.

[0148] In some embodiments, the arecaidine salt is obtained by neutralizing arecaidine with a coordinating acid.

[0149] In some embodiments, the coordinating acid of the arecaidine salt is selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0150] In some embodiments, the molar ratio of the arecaidine to the coordinating acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0151] In some embodiments, when manufacturing the chewing gum, based on the total mass of the raw materials of the chewing gum, the mass percentage of the arecaidine salt is 0.02% - 2%, preferably 0.02% - 1.6%, more preferably 0.02% - 1.2%, more preferably 0.02% - 1%, more preferably 0.1% - 1%, more preferably 0.2% - 1%, more preferably 0.4% - 1%.

[0152] In some embodiments, when manufacturing the chewing gum, the objects added to the arecaidine salt include a gum base.

[0153] In some embodiments, when manufacturing the chewing gum, the mass percentage of the gum base is 20% to 75% based on the total mass of the raw materials of the chewing gum, preferably 20% to 70%, more preferably 20% to 60%, more preferably 20% to 50%, more preferably 25% to 50%, more preferably 30% to 50%, more preferably 35% to 50%, and more preferably 35% to 45%.

[0154] In some embodiments, the substances added to the arecoline salt also include sweeteners.

[0155] In some embodiments, the sweetener is selected from at least one of the following: granulated sugar, rock sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame potassium, sucralose, steviol glycoside, neotame.

[0156] In some embodiments, when manufacturing the chewing gum, the sweetener is 20% to 75% by mass, preferably 20% to 70%, more preferably 20% to 60%, more preferably 20% to 50%, more preferably 25% to 50%, more preferably 25% to 40%, more preferably 25% to 35%, and more preferably 30% to 35%, based on the total mass of the raw materials for the chewing gum.

[0157] In some embodiments, the material added to the arecoline salt also includes a filler material.

[0158] In some embodiments, the filler material is selected from at least one of the following: sodium carbonate, sodium bicarbonate, potassium carbonate, calcium carbonate, dicalcium phosphate, and sodium dihydrogen phosphate.

[0159] In some embodiments, when manufacturing the chewing gum, the filler material accounts for 0.03% to 23% of the total mass of the raw materials of the chewing gum, preferably 0.03% to 20%, more preferably 0.03% to 15%, more preferably 0.03% to 10%, more preferably 0.5% to 10%, more preferably 1% to 10%, more preferably 1.5% to 10%, more preferably 2% to 8%, and more preferably 2% to 6%.

[0160] In some embodiments, the substances added to the arecoline salt also include flavoring agents.

[0161] In some embodiments, the flavoring agent is selected from at least one of the following: mint, spearmint, cinnamon, borneol, essence.

[0162] Embodiment Ten:

[0163] Embodiment Ten of the present invention provides a chewing gum, the raw materials of which include arecoline salt and a gum base.

[0164] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a coordinating acid.

[0165] In some embodiments, the coordinating acid of the arecoline salt is selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0166] In some embodiments, the molar ratio of the arecoline to the coordinating acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0167] In some embodiments, based on the total mass of the raw materials, the mass percentage of the arecoline salt is 0.02% - 2%, preferably 0.02% - 1.6%, more preferably 0.02% - 1.2%, more preferably 0.02% - 1%, more preferably 0.1% - 1%, more preferably 0.2% - 1%, more preferably 0.4% - 1%.

[0168] In some embodiments, the mass percentage of the adhesive base is 20% to 75% based on the total mass of the raw materials, preferably 20% to 70%, more preferably 20% to 60%, more preferably 20% to 50%, more preferably 25% to 50%, more preferably 30% to 50%, more preferably 35% to 50%, and more preferably 35% to 45%.

[0169] In some implementations, the raw material also includes a sweetener.

[0170] In some embodiments, the sweetener is selected from at least one of the following: granulated sugar, rock sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame potassium, sucralose, steviol glycoside, neotame.

[0171] In some embodiments, the sweetener is 20% to 75% by weight of the total mass of the raw materials, preferably 20% to 70%, more preferably 20% to 60%, more preferably 20% to 50%, more preferably 25% to 50%, more preferably 25% to 40%, more preferably 25% to 35%, and more preferably 30% to 35%.

[0172] In some embodiments, the raw material also includes filler material.

[0173] In some embodiments, the filler material is selected from at least one of the following: sodium carbonate, sodium bicarbonate, potassium carbonate, calcium carbonate, dicalcium phosphate, and sodium dihydrogen phosphate.

[0174] In some embodiments, the filler material comprises 0.03% to 23% by mass of the total raw materials, preferably 0.03% to 20%, more preferably 0.03% to 15%, more preferably 0.03% to 10%, more preferably 0.5% to 10%, more preferably 1% to 10%, more preferably 1.5% to 10%, more preferably 2% to 8%, and more preferably 2% to 6%.

[0175] In some embodiments, the raw materials also include flavoring agents.

[0176] In some embodiments, the flavoring agent is selected from at least one of the following: mint, spearmint, cinnamon, borneol, and flavoring.

[0177] Example 1:

[0178] Chewing gum was prepared according to the following formula: 54 wt% gum base, 23 wt% sugar powder, 14 wt% glucose syrup, 4 wt% potassium carbonate, 3 wt% mint flavoring, 1 wt% menthol, and 1 wt% arecoline salt.

[0179] Preparation method: Heat the gum base to 70~105℃, put it in a mixer and stir, add sugar powder, and let the temperature drop to 60~80℃, then add buffer, additives, glucose syrup and arecoline salt, and finally roll it into sheets to form the finished product.

[0180] Example 2:

[0181] Xylitol chewing gum was prepared according to the following formula: gum base 54wt%, xylitol 23wt%, non-sucrose 14wt%, potassium carbonate 4wt%, mint flavoring 3wt%, menthol 1wt%, arecoline salt 1wt%.

[0182] Preparation method: Heat the gum base to 70~105℃, put it in a mixer and stir, add xylitol and non-sucrose, and let the temperature drop to 60~80℃, then add buffer, additives and arecoline salt, and finally roll it into sheets to form the finished product.

[0183] The chewing gum prepared by the above method was compared with ordinary chewing gum in terms of its edibility and sensory quality. The chewing gum prepared by the above method can produce a similar effect to chewing betel nut, with low irritation and a good taste. Since this chewing gum does not contain lime powder and cellulose, it avoids the problems of oral mucosal abrasion and irritation and the induction of oral diseases that occur when chewing betel nut.

[0184] Implementation Method Eleven:

[0185] Embodiment 11 of the present invention provides the use of arecoline salt in the preparation of beverages.

[0186] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a complexing acid.

[0187] In some embodiments, the counter acid of the arecoline salt is selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0188] In some embodiments, the molar ratio of the arecoline to the counter acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0189] In some embodiments, when preparing the beverage, based on the total mass of the beverage, the mass percentage of the arecoline salt is 0.01% - 0.5%, preferably 0.01% - 0.4%, more preferably 0.01% - 0.3%, more preferably 0.01% - 0.2%, more preferably 0.05% - 0.2%.

[0190] In some embodiments, when preparing the beverage, the substances added to the arecoline salt include water.

[0191] In some embodiments, when preparing the beverage, based on the total mass of the beverage, the mass percentage of the water is 75% - 90%.

[0192] In some embodiments, when preparing the beverage, the substances added to the arecoline salt further include functional ingredients.

[0193] In some embodiments, the functional ingredients are selected from at least one of the following: Momordica grosvenori concentrated juice, natural menthol, Glycyrrhiza uralensis concentrated juice, Lonicera japonica concentrated juice, Chrysanthemum morifolium extract, Pueraria lobata extract, Eriobotrya japonica raw pulp.

[0194] In some embodiments, based on the total mass of the beverage, the mass percentage of the functional ingredients is 0.5% - 2%.

[0195] In some embodiments, when preparing the beverage, the substances added to the arecoline salt also include an acidity regulator.

[0196] In some embodiments, the acidity regulator is selected from at least one of the following: tartaric acid, malic acid, citric acid, and sodium citrate.

[0197] In some embodiments, when preparing the beverage, the acidity regulator is 0.1% to 5% by mass, based on the total mass of the beverage.

[0198] In some embodiments, when preparing the beverage, the substances added to the arecoline salt also include a sweetener.

[0199] In some embodiments, the sweetener is selected from at least one of the following: granulated sugar, rock sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame potassium, sucralose, steviol glycoside, neotame.

[0200] In some embodiments, when preparing the beverage, the sweetener is 0.5% to 5% by mass, based on the total mass of the beverage.

[0201] In some embodiments, when preparing the beverage, the substances added to the arecoline salt also include antioxidants.

[0202] In some embodiments, the antioxidant is selected from at least one of the following: ascorbic acid, sodium isoascorbate, vitamin C, and vitamin E.

[0203] In some embodiments, when preparing the beverage, the antioxidant is 0.05% to 0.15% by mass of the total mass of the beverage.

[0204] In some embodiments, when preparing the beverage, the contents added to the arecoline salt also include a preservative.

[0205] In some embodiments, the preservative is selected from at least one of the following: sodium benzoate, sodium sorbate, and potassium sorbate.

[0206] In some embodiments, when preparing the beverage, based on the total mass of the beverage, the mass percentage of the preservative is 0.01% to 0.05%.

[0207] In some embodiments, when preparing the beverage, the substances added to the arecaidine salt further include edible essence.

[0208] In some embodiments, when preparing the beverage, based on the total mass of the beverage, the mass percentage of the edible essence is 0.5% to 5%.

[0209] Embodiment Twelve:

[0210] Embodiment Twelve of the present invention provides a beverage, the raw materials of which include arecaidine salt and water.

[0211] In some embodiments, the arecaidine salt is obtained by neutralizing arecaidine with a coordinating acid.

[0212] In some embodiments, the coordinating acid of the arecaidine salt is selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0213] In some embodiments, the molar ratio of the arecaidine to the coordinating acid is n; wherein, the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0214] In some embodiments, based on the total mass of the beverage, the mass percentage of the arecaidine salt is 0.01% to 0.5%, preferably 0.01% to 0.4%, more preferably 0.01% to 0.3%, more preferably 0.01% to 0.2%, more preferably 0.05% to 0.2%.

[0215] In some embodiments, the water accounts for 75% to 90% of the total mass of the beverage.

[0216] In some embodiments, the raw material also includes functional ingredients.

[0217] In some embodiments, the functional ingredient is selected from at least one of the following: monk fruit concentrate, natural menthol, licorice concentrate, honeysuckle concentrate, chrysanthemum extract, kudzu root extract, and loquat pulp.

[0218] In some implementations, the functional ingredient is 0.5% to 2% by mass.

[0219] In some embodiments, the raw material also includes an acidity regulator.

[0220] In some embodiments, the acidity regulator is selected from at least one of the following: tartaric acid, malic acid, citric acid, and sodium citrate.

[0221] In some embodiments, the acidity regulator is 0.1% to 5% by mass.

[0222] In some implementations, the raw material also includes a sweetener.

[0223] In some embodiments, the sweetener is selected from at least one of the following: granulated sugar, rock sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame potassium, sucralose, steviol glycoside, neotame.

[0224] In some embodiments, the sweetener is 0.5% to 5% by mass.

[0225] In some embodiments, the raw material also includes an antioxidant.

[0226] In some embodiments, the antioxidant is selected from at least one of the following: ascorbic acid, sodium isoascorbate, vitamin C, and vitamin E.

[0227] In some embodiments, the antioxidant is 0.05% to 0.15% by mass.

[0228] In some implementations, the raw material also includes a preservative.

[0229] In some embodiments, the preservative is selected from at least one of the following: sodium benzoate, sodium sorbate, and potassium sorbate.

[0230] In some embodiments, the preservative is present in a mass percentage of 0.01% to 0.05%.

[0231] In some implementations, the raw materials also include edible flavorings.

[0232] In some embodiments, the edible flavoring is 0.5% to 5% by mass.

[0233] Example 1:

[0234] The beverage was prepared according to the following formula: 0.1 wt% arecoline salt, 88 wt% water, 1 wt% honeysuckle concentrate, 1 wt% licorice concentrate, 2 wt% citric acid, 2 wt% sodium citrate, 3 wt% steviol glycosides, 0.05 wt% vitamin C, 0.05 wt% sodium sorbate, and 2.8 wt% edible flavoring.

[0235] Preparation method: Mix arecoline salt with water, honeysuckle concentrate, licorice concentrate, citric acid, sodium citrate, steviol glycosides, vitamin C, sodium sorbate, and edible flavoring to make a beverage.

[0236] The beverage prepared by the above method retains a variety of nutrients beneficial to the human body from honeysuckle and licorice. The beverage is rich in arecoline, arecoline polyphenols and other components. It has a good taste and has a variety of effects such as invigorating the spleen and replenishing qi, clearing heat and detoxifying, relieving phlegm and cough, and relieving pain.

[0237] This written description uses examples to disclose the invention, including the best mode, and also enables those skilled in the art to make and use the invention. The patentable scope of the invention is defined by the claims and may include other embodiments conceived by those skilled in the art. Such other embodiments are intended to be within the scope of the claims if they have structural elements that are no different from the literal language of the claims, or if they include equivalent structural elements that are not substantially different from the literal language of the claims. All references cited herein are incorporated herein by reference to the extent that they will not cause inconsistency.

Claims

1. A betel nut-flavored product, said product being an aerosol forming matrix or a popping bead used in aerosol-generating products, comprising arecoline salt, wherein the arecoline salt is present in a mass percentage of 1% to 5% based on the total mass of the raw materials of said product.

2. The product as claimed in claim 1, wherein the arecoline salt is obtained by neutralizing arecoline with a complex acid.

3. The product as claimed in claim 2, wherein the arecoline salt contains a complex acid selected from at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, stearic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, aspartamine, glutamine, threonine, aspartic acid, glutamine, lysine, arginine, and histamine.

4. The product as claimed in claim 2, wherein the molar ratio of arecoline to the complex acid is n; wherein, The value of n is in the range of 0 < n ≦ 10.

5. The product as described in any one of claims 1 to 4, wherein the arecoline salt is 2% to 10% by mass based on the total mass of the raw materials of the product.

6. The article of claim 1, wherein the aerosol forming matrix is ​​a liquid phase for atomization using any one of a heated atomizing device, an ultrasonic atomizing device, an air compression atomizing device, or a press-type spraying device to generate an aerosol.

7. The article as claimed in claim 1, wherein the aerosol generating matrix is ​​a solid phase and is configured to generate an inhalable aerosol when heated to below its ignition point.