System and method using coupled multi-modal sensory stimulation to enhance physiological feedback

TWI943681BActive Publication Date: 2026-10-21EXEBRAIN CO LTD
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Patent Information

Application Number
TW114137417
Authority / Receiving Office
TW · TW
Patent Type
Patents
Current Assignee / Owner
Filing Date
2025-09-26
Publication Date
2026-10-21
Estimated Expiration
2045-09-25

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Abstract

This invention discloses a system and method for enhancing physiological feedback training through multimodal sensory stimulation coupling. The system includes a sensing module configured to detect a physiological signal in a subject; a computation module electrically connected to the sensing module and configured to analyze the physiological signal and calculate a brainwave index related to a Gamma band; a stimulation module electrically connected to the computation module and configured to generate a sensory stimulus with a non-invasive Gamma band; and a control module electrically connected to the stimulation module and configured to simultaneously receive the physiological signal and dynamically adjust an output parameter of the stimulation module based on the result of the computation module's analysis of the physiological signal. This achieves synchronization and training of the brain's functional network.
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Claims

1. A system for enhancing physiological feedback training through multimodal sensory stimulation coupling, comprising: A sensing module configured to detect a subject to obtain a physiological signal, the physiological signal including at least an electroencephalogram (EEG); a calculation module electrically connected to the sensing module and configured to analyze the physiological signal and calculate a brainwave index related to a Gamma band; a stimulation module electrically connected to the calculation module and configured to generate a sensory stimulus having a non-invasive Gamma band; and a control module electrically connected to the stimulation module and configured to simultaneously receive the physiological signal and dynamically adjust an output parameter of the stimulation module based on a result of the calculation module's analysis of the physiological signal, wherein the output parameter includes parameters, proportions, and modes of frequency range, intensity, phase, and modality-weighted Gamma stimulation modal output. The control module determines whether the brainwave index has reached a preset target value or a training standard. If the brainwave index has reached the training standard, the sensory stimulation output with the Gamma frequency band is maintained. If the brainwave index has not reached the training standard, the control module automatically adjusts the output parameters of the stimulation module and returns to the sensory stimulation step to promote further synchronization of brainwaves.

2. The system for enhancing physiological feedback training through multimodal sensory stimulation coupling as described in claim 1, wherein, This physiological signal further includes one of the following: heart rate variability (HRV), respiration, and skin conductance.

3. The system for enhancing physiological feedback training through multimodal sensory stimulation coupling as described in claim 1, wherein, The brainwave indicators include obtaining an energy distribution in a specific frequency band through power spectral density (PSD), describing a modulation relationship between a low-frequency phase and a high-frequency amplitude through phase-amplitude coupling (PAC), phase synchronization or coherence, instantaneous phase locking value (PLV), mutual information, or functional connectivity (FC).

4. The system for enhancing physiological feedback training through multimodal sensory stimulation coupling as described in claim 1, wherein, The stimulation module includes an auditory stimulation device placed around the ear, a visual stimulation device placed around the eye, and a tactile stimulation device placed on the skin. The sensory stimulation includes any modality of vision, hearing, touch, or smell, any combination of two, or three or more simultaneously.

5. The system for enhancing physiological feedback training through multimodal sensory stimulation coupling as described in claim 1 further includes a feedback module electrically connected to the stimulation module and configured to instantly present a physiological response of the subject on a screen interface through the sensory stimulation of vision or hearing.

6. A method for enhancing physiological feedback training through multimodal sensory stimulation coupling, comprising: A signal acquisition step: Using a sensing module to detect a subject's physiological data to acquire a physiological signal in real time, the physiological signal including at least one of electroencephalogram (EEG), heart rate variability (HRV), respiration, and skin conductance response; A sensory stimulation step: Applying a sensory stimulus in the Gamma band to the subject through a stimulation module; An analysis and calculation step: Analyzing a brainwave index of the physiological data through a calculation module and calculating an index in the Gamma band based on the brainwave EEG signal of the brainwave index; A judgment step: A control module determines whether the brainwave index has reached a preset target value or a training standard; if the brainwave index has reached the training standard, the output of the sensory stimulation with the Gamma frequency band is maintained; if the brainwave index has not reached the training standard, the control module automatically adjusts a stimulation parameter of the stimulation module and returns to the sensory stimulation step to promote further synchronization of brainwaves; and a feedback step: A feedback module presents the subject's physiological response on a screen interface in real time through the sensory stimulation of vision or hearing.

7. The method for enhancing physiological feedback training through multimodal sensory stimulation coupling as described in claim 6, wherein, The signal acquisition process includes electroencephalography (EEG) recording.

8. The method for enhancing physiological feedback training through multimodal sensory stimulation coupling as described in claim 6, wherein, The sensory stimulation includes visual flashes, auditory dots, or tactile vibrations, and the stimulation parameters include brightness, volume, vibration intensity, phase, or modal combinations.

9. The method for enhancing physiological feedback training through multimodal sensory stimulation coupling as described in claim 6, wherein, This metric includes a power spectral density, a phase synchronization, or a coupling degree.

10. The method for enhancing physiological feedback training through multimodal sensory stimulation coupling as described in claim 6, wherein, The screen interface is presented through a brain region reality, which includes one of augmented reality, virtual reality, mixed reality, and extended reality.

Citation Information

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