Breast Cancer Prognostic Assessment System

Abstract

A breast cancer prognostic assessment system addresses the problems of complex data analysis and difficult interpretation in conventional breast cancer prognostic assessments. The system includes: a patient data input unit receiving clinical information from a patient; a gene information receiving unit receiving gene expression data from the patient; a clinical information integration unit coupled to the patient data input unit and the gene information receiving unit to integrate the clinical information and the gene expression data; a prognostic assessment module coupled to the clinical information integration unit to establish a prognostic assessment result based on the integrated data; and a result output unit coupled to the prognostic assessment module to output the prognostic assessment result and a risk level. This improves assessment efficiency and facilitates the interpretation of assessment results.

Claims

1. A breast cancer prognostic assessment system, comprising: a patient data input unit for receiving clinical information of a patient; a gene information receiving unit for receiving gene expression data of the patient; a clinical information integration unit coupled to the patient data input unit and the gene information receiving unit to integrate the clinical information and the gene expression data; a prognostic assessment module coupled to the clinical information integration unit to establish a prognostic assessment result based on the integrated clinical information and the gene expression data; and a result output unit coupled to the prognostic assessment module to output the prognostic assessment result and a risk level.

2. As in request item 1, a breast cancer prognostic assessment system, wherein, This clinical information includes at least one of the following: age, breast cancer stage, and breast cancer molecular subtype.

3. As in request item 1, a breast cancer prognostic assessment system, wherein, The prognostic assessment results include a risk score, a survival prediction, and a nomogram for the patient.

4. As in request item 1, a breast cancer prognostic assessment system, wherein, The prognostic assessment module includes a data preprocessing unit, a risk assessment unit, a prediction model unit, and a line graph creation unit.

5. As in request item 4, a breast cancer prognostic assessment system, wherein, The risk assessment unit establishes a risk score for one of the patients based on the clinical information and the gene expression data.

6. As in request item 5, a breast cancer prognostic assessment system, wherein, The predictive model unit generates a survival rate prediction for one of the patients based on the risk score.

7. As in request item 6, a breast cancer prognostic assessment system, wherein, The nomogram building unit generates a corresponding nomogram based on the survival rate prediction.

8. A breast cancer prognostic assessment system as requested in items 3 or 5, wherein, The output unit distinguishes different risk levels based on the risk score.

9. The breast cancer prognostic assessment system of claim 1 further includes a display interface coupled to the result output unit to display the prognostic assessment result of the patient.

10. The breast cancer prognostic assessment system of claim 1 further includes a data storage unit electrically coupled to the clinical information integration unit and the result output unit to store the clinical information, the gene expression data, the prognostic assessment results, the risk level and its historical records.

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