RECOMBINANT PLASMID, RECOMBINANT FOOT-AND-MOUTH VIRUS TYPE O, AND FOOT-AND-MOUTH VACCINE CONTAINING THIS VIRUS, ARE PREPARED FROM THIS PLASMID.

Abstract

The proposed vaccine for foot-and-mouth disease (FMD) contains recombinant FMD viruses and antigens isolated and purified from these viruses. In the early stages of vaccination, a humoral immune response is generated simultaneously through the creation of a strong cellular immune response. During the appearance of maternally derived antibodies (MDAs), B cell receptors are stimulated. Through this, a vaccine product capable of generating active immunity and overcoming the interference of maternally derived antibodies could be proposed, useful for preventing or treating FMD using the same product.