PYROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES ARE USEFUL FOR CANCER TREATMENT AND THEY ARE CONTAINING THEM IN PHARMACEUTICALS

Abstract

The invention relates to a chemical compound or formulation (i) (e.g., a compound or pharmaceutical salt, and / or hydrate, and / or cocs, and / or pharmaceutical mixture of the compound) that inhibits epidermal growth factor receptor (EGFR, ERBB1) and / or human epidermal growth factor receptor 2 (HER2, ERBB2). These chemical compounds are useful, for example, for the treatment of a condition, disease or disorder in which increased (e.g., excessive) EGFR and / or HER2 activation contributes to the pathology and / or symptoms and / or progression of the condition, disease or disorder (e.g., cancer) in subjects (e.g., humans). The invention also proposes a pharmaceutical product containing these compounds.