N-substituted-4-[3-(quinolin-6-yl)ureido] benzoylhydrazide derivative, preparation method and application thereof
ZA202510936BActive Publication Date: 2026-08-26XINGZHI COLLEGE ZHEJIANG NORMAL UNIV
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Patent Information
- Application Number
- ZA202510936
- Authority / Receiving Office
- ZA · ZA
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2025-12-18
- Publication Date
- 2026-08-26
- Estimated Expiration
- 2045-12-18
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Abstract
The present invention belongs to the technical field of medicine, and particularly relates to an N-substituted-4-[3-(quinolin-6-yl)ureido] benzoylhydrazide derivative, a preparation method and an application thereof. The derivative has a structure represented by a general formula I. In the present invention, the derivative is capable of inhibiting expression of nuclear receptor subfamily 4 group A member 1 (Nur77) in a concentration-dependent manner.
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