Title - A MOLECULE N-(3-CHLORO-1-(PYRIDIN-3-YL)-1H-PYRAZOL-4-YL)-2-(METHYLSULFONYL)PROPANAMIDE, EXCLUDING ITS THERAPEUTIC APPLICATION IN HUMANS, AND COMPOSITION COMPRISING IT

Abstract

This description pertains to the field of molecules that have pesticidal utility against pests in the phyla Arthropoda, Mollusca, and Nematoda, processes for producing such molecules, pesticide compositions containing such molecules, and processes for using such pesticide compositions against such pests. These pesticide compositions may be used, for example, as acaricides, insecticides, arachnicides, molluscicides, and nematicides. This document describes a molecule having formula (1).

Description

-03'00' Molecules that have pesticide use, and compositions and processes related to them Cross-reference to related applications This application claims priority and benefit from the United States provisional application serial number 62 / 682248, filed on June 8, 2018. The full contents of the above-mentioned application are incorporated herein by reference. Description field This description refers to the field of molecules that have pesticidal utility against pests in the phyla Arthropoda, Mollusca, and Nematoda; processes for producing such molecules; pesticide compositions containing such molecules; and processes for using such pesticide compositions against such pests. These pesticide compositions may be used, for example, as acaricides, insecticides, arachnicides, molluscicides, and nematicides. Background to this description: “Many of the most dangerous human diseases are transmitted by insect vectors” (Rivero et al.). “Historically, malaria, dengue fever, yellow fever, plague, filariasis, louse-borne typhus, trypanosomiasis, leishmaniasis, and other vector-borne diseases were responsible for more human illness and death in the 17th and early 20th centuries than all other causes combined” (Gubler). Vector-borne diseases are IF-2019-63795218-APN-ANP#INPI Page 1 of 82 Vectors are responsible for approximately 17% of global parasitic and infectious diseases. Malaria alone causes more than 800,000 deaths annually, 85% of which occur in children under five years of age. Approximately 50 to 100 million cases of dengue fever occur each year. An additional 250,000 to 500,000 cases of dengue hemorrhagic fever occur annually (Matthews). Vector control plays a critical role in the prevention and control of infectious diseases. However, insecticide resistance, including multidrug resistance, has emerged in all insect species that are important vectors of human diseases (Rivero et al.). Recently, more than 550 arthropod species have developed resistance to at least one pesticide (Whalon et al.). Furthermore, insect resistance cases continue to far exceed herbicide and fungicide resistance cases (Sparks et al.). Each year, insects, plant pathogens, and weeds destroy more than 40% of all food production. This loss occurs despite the application of pesticides and the use of a wide variety of non-chemical controls, such as crop rotations and biological controls. If only some of this food could be preserved, it could be used to feed the more than three billion people worldwide who suffer from malnutrition (Pimental). Plant-parasitic nematodes are among the most widespread pests and are frequently among the most insidious and costly. Losses attributable to nematodes have been estimated at approximately 9% in developed countries and approximately 15% in developing countries. However, in the United States, a study of 35 states across various crops indicated nematode-related losses of up to 25% (Nicol et al.). It should be noted that gastropods (slugs and snails) are pests of less economic importance than other arthropods or nematodes, but in certain places they can substantially reduce yields and seriously affect the quality of the IF-2019-63795218-APN-ANP#INPl Page 2 of 82 harvested products, as well as transmitting diseases to humans, animals, and plants. Although only a few dozen gastropod species are serious regional pests, a number of species are important pests on a global scale. In particular, gastropods affect a wide variety of agricultural and horticultural crops, such as crops in arable, grazing, and fiber fields; vegetables; fruits of shrubs and trees; herbs; and ornamentals (Speiser). Termites cause damage to all types of public and private structures, as well as to agricultural and forestry resources. In 2005, it was estimated that termites cause more than US$50 billion in damage worldwide each year (Korb). Consequently, for many reasons, including those mentioned above, there is a continuing need for the development of new pesticides, which is costly (estimated at approximately US$256 million per pesticide in 2010), time-consuming (on average approximately 10 years per pesticide), and difficult (CropLife America). Some references cited in this description CropLife America, The Cost of New Agrochemical Product Discovery, Development & Registration, and Research & Development predictions for the Future, 2010. Drewes, M., Tietjen, K., Sparks, T.C., High-Throughput Screening in Agrochemical Research, Modern Methods in Crop Protection Research, Parte I, Methods for the Design y Optimization of New ingrediente activos, Editado por Jeschke, P., Kramer, W., Schirmer, U., y Matthias W., págs. 1-20, 2012. Gubler, D., Resurgent Vector-Borne Diseases as a Global Health Problem, Emerging Infectious Diseases, Vol. 4, núm. 3, págs. 442-450, 1998. Korb, J., Termites, Current Biology, Vol. 17, núm. 23, 2007. IF-2019-63795218-APN-ANP#INPI Página 3 de 82 Matthews, G., Integrated Vector Management: Controlling Vectors of Malaria y Other Insect Vector Borne Diseases, Cap. 1, pág. 1, 2011. Nicol, J., Turner S., Coyne, L, den Nijs, L, Hocksland, L, Tahna-Maafi, Z., Current Nematode Threats to World Agriculture, Genomic y Molecular Genetics of Plant Nematode Interactions, págs. 21—43, 2011. Pimental, D., Pest Control in World Agriculture, Agricultural Sciences - Vol. II, 2009. Rivero, A., Vezilier, J., Weill, M., Read, A., Gandon, S., Insect Control of VectorBorne Diseases: When is Insect Resistance a Problem? Public Library of Science Pathogens, Vol. 6, núm. 8, págs. 1-9, 2010. Sparks T.C., Ñauen R_, IRAC: Mode of action classification y insecticide resistance management, Pesticide Biochemistry y Physiology (2014) disponible en línea 4 de diciembre de 2014. Speiser, B., Molluscicides, Encyclopedia of Pest Management, Cap. 219, págs. 506-508, 2002. Whalon, M., Mota-Sanchez, D., Hollingworth, R., Analysis of Global Pesticide Resistance in Arthropods, GlobalPesticide Resistance in Arthropods, Cap. 1, pág. 5-33, 2008. Definiciones usadas en esta descripción The examples given in these definitions are generally not exhaustive and should not be interpreted as limiting this description. It is understood that a substituent must comply with the rules of chemical bonding and spherical compatibility restrictions with respect to the particular molecule to which it is attached. These definitions will be used only for the purposes of this description. IF-2019-63795218-APN-ANP#INPI Page 4 of 82 The phrase “active ingredient” refers to a material that has useful activity in pest control and / or that is useful in helping other materials to have better pest control activity. Examples of such materials include, but are not limited to, acaricides, algaecides, feeding inhibitors, avicides, bactericides, bird repellents, chemosterilants, fungicides, herbicide protectants, herbicides, insect attractants, insect repellents, insecticides, mammal repellents, mating disruptors, molluscicides, nematicides, plant activators, plant growth regulators, rodenticides, synergists, and virucides (see alanwood.net). Specific examples of such materials include, but are not limited to, the materials listed in the alpha active ingredients group. The phrase “alpha group of the active ingredient” (hereinafter “AIGA”) refers collectively to the following materials: (1) (3-ethoxypropyl)mercury bromide, 1,2-dibromoethane, 1,2-dichloroethane, 1,2-dichloropropane, 1,3-dichloropropene, 1-MCP, 1-methylcyclopropene, 1-naphthol, 2(octylthio)ethanol, 2,3,3-TPA, acid 2,3,5-triiodobenzoic, 2,3,6-TBA, 2,4,5-T, 2,4,5-TB, 2,4,5-TP, 2,4-D, 2,4-DB, 2,4-DEB, 2,4-DEP, 2,4-DES, 2,4-DP, 2,4-MCPA, 2,4-MCPB, 2ÍP, 2-methoxyethylmercury chloride, 2-phenylphenol, 3,4-DA, 3,4-DB, 3,4-DP, 3,6-dichloropicolinic acid, 4-aminopyridine, 4-CPA, 4-CPB, 4-CPP, 4-hydroxyphenethyl alcohol, 8-hydroxyquinoline sulfate, 8-phenylmercuroxyquinoline, abamectin, abamectinaminomethyl, abscisic acid, ACC, acephate, acequinocyl, acetamiprid, acethion, acetochlor, acetophenate, acetofos, acetoprol, acibenzolar, acifluorphen, acloniphene, ACN, acrep, acrinathrin, acrolein, acrylonitrile, acinonapyr, acipetacs, afidopyropene, afoxolaner, alachlor, alanap, alanicarb, albendazole, aldicarb sulfone, aldimorph, aldoxycarb, aldrin, allethrin, allicin, alidochlor, allosamidine, aloxidim,alil alcohol, alixicarb, alorac, alpha—cypermethrin, a / fa-endosulfano, alfametrina, altretamina, fospfuro de aluminio, fospfuro de aluminio, ametoctradina, ametridiona, ametrina, ametrin, amibuzina, amicarbazona, amicartiazol, amiditión, amidoflumet, amidosulfurón, aminocarb, IF-2019-63795218-APN-ANP#INPJ Page 5 of 82 aminocyclopyrachlor, aminopyralid, aminopyrifen, aminotriazole, amiprofos-methyl, amiprofos, amiprofos-methyl, amisulbrom, amiton, amitraz, amitrol, ammonium sulfamate, amobam, amorphous silica gel, amorphous silicon dioxide, ampropylfos, AMS, anabasine, ancimidol, anilazine, anilofos, anisaran, anthraquinone, antu, afolara, aramite, arprocarb, arsenious oxide, asomara, aspirin, asulam, atidathion, atraton, atrazine, aureofungin, avermectin B1, AVG, aviglicin, azaconazole, azadirachtin, azaphenidine, azamethiphos, azidithion, azimsulfuron, azinphosethyl, azinphos-ethyl azinphosmethyl, azinphos-methyl, aziprotryn, aziprotrine, azitiram, azobenzene, azocyclotin, azotoate, azoxystrobin, bachmedesh, barban, barbanate, barium hexafluorosilicate, barium polysulfide, barium silicofluoride, barthrine, basic copper carbonate, basic copper chloride, basic copper sulfate, BCPC, beflubutamide, beflubutamide-M, benalaxyl, benalaxyl-M, benazoline, bencarbazone, benclothiazbendaqingbingzhi, bendiocarb, bendioxide, benefin, benfluralin, benfuracarb, benfuresate, benmihuangcaoan, benodanil, benomyl, benoxacor, benoxafos, benquinox, bensulfuron, bensulide, bensultap, bentaluron, bentazon, bentazone, bentiavalicarb, bentiazol, benthiocarb, bentranil, benzadox, benzalkonium chloride, benzamacril, benzamizole, benzamorph, benzene hexachloride, benzfendizone, benzimine, benzipram, benzobicyclon, benzoepin, benzofenap, benzofluor, benzohydroxamic acid, benzomate, benzophosphate, benzothiadiazole, benzovindiflupyr, benzoximate, benzoylprop, benzpyrimoxan, benzthiazuron, benzuocaotong, benzyl benzoate, benziladenine, berberine, beta-cyfluthrin, oeta-cypermethrin, betoxazine, BHC, bialafos, biciclopyrone, bifenazate, bifenox, bifenthrin, bifujunzhi, bilanafos, binapacril, bingqingxiao, bioallethrin, bioethanenomethrin, biopermethrin, bioresmethrin, biphenyl, bisazir, bismerthiazole, bismerthiazole-copper, bisphenylmercury methylenedi(x-naphthalene-ysulfonate), bisspirac,bistrifluron, bisultap, bitertanol, bithinol, bixafen, bixlozone, blasticidinS, borax, Bordeaux mixture, boric acid, boscalid, BPPS, brassinolide, brassinolide-ethyl, brevicomin, brodifacoum, brofenprox, brofenvalerate, broflanilide, brofluthrinate, bromacil, bromadiolone, bromclofos, bromethalin, bromethrin, bromacil, bromfevinphos. IF-2019-63795218-APN-ANP#INPI Page 6 of 82 bromoacetamida, bromobonil, bromobutida, bromociclen, bromocicleno, bromo-DDT, bromofenoxim, bromofos, bromometano, bromofos, bromofos-etil, bromopropilato, bromotalonil, bromoxinil, brompirazon, bromuconazol, bronopol, BRP, BTH, bucarpolato, bufencarb, buminafos, bupirimato, buprofezin, mezcla de Burgundy, busulfán, busulfán, butacarb, butaclor, butafenacil, butam, butamifos, buten-fipronil, butatiofos, butenaclor, buten-fipronil, butetrin, butidiazol, buitiobato, butiuron, butifos, butocarboxim, butonato, butopironoxil, butoxicarboxim, butralina, butrizol, butroxidim, buturon, butilamina, butilato, butylclorofos, butileno-fipronil, ácido cacodilico, cadusafos, cafenstrol, calciferol, arsenato de calcio, clorato de calcio, cianamida de calcio, cyanida de calcio, polysulfuro de calcio, calvinfos, cambendiclor, campeclor, campfor, captafol, captan, carbarn, cabamorf, carbanolato, carbaril, carbarilo, carbasulam, carbation, carbendazim, carbendazol, carbetamide, carbofenotión, carbofurano,carbon disulfide, carbon tetrachloride, carbonyl sulfide, carbophenothion, carbofos, carbosulfan, carboxazole, carboxide, carboxin, carfentrazone, carpropamide, cartap, carvacrol, carvone, CAVP, CDAA, CDEA, CDEC, celocidine, CEPC, ceralure, cerenox, cevadilla, Cheshunt mixture, chinalfos, chinalfos-methyl, chinomethionate, chinomethionate, chiralaxyl, chitosan, clobenthiazone, chlormethoxyphen, chloralose, chloramben, chloramine phosphorus, chloramphenicol, chloraniformethane, chloranil, chloranocryl, chlorantraniliprole, chlorazifop, chlorazine, chlorbenside, chlorbenzuron, chlorbiciclen, chlorbromuron, chlorbufam, chlordane, chlordecon, chlordimeform, chlorempentrin, chloretazate chloretefon, chlorethoxifos, chloreturon, chlorfenac, chlorfenapyr, chlorfenazol, chlorphenetol, chlorfenidim, chlorfenprop, chlorfenson, chlorfensulfide, chlorfenvinphos, chlorfenvinfos-methyl, chlorfluazuron, chlorflurazole, chlorflurecol, chlorfluren, chlorflurenol, chloridazon, chlorimuron, chlorinate, chlor-IPC, chlormefos, chlormequat, chlormesulone,chlormethoxynyl, chlornidine, chlornitrofen, chloroacetic acid, chlorobenzylate, chlordinitronaphthalenes, chlorophenizon, chloroform, chlorbemuform, chloromethiuron, chloroneb, chlorophacinone, chlorofos, chloropicrin, chloronpon, chloroprahletrin, chloropropylate, chlorothalonil, chlorotoluron, chloroxyphenidim, chloroxuron, chloroxinil, chlorphonium, chlorfoxim, chlorprazofos IF-2019-63795218-APN-ANP#INPÍ Page 7 of 82 chlorprocarb, chlorpropham, chlorpyrifos, chlorpyrifos-methyl, chlorquinox, chlorsulfuron, chlortal, chlorthiamide, chlorthiofos, chlortoluron, clozolinate, chitosan, colacalciferol, choline chloride, chromafenozide, cycloheximide, cimectacarb, cimetacarb, cinerin I, cinerin II, cinerins, cinidon-ethyl, cinmethylin, cinosulfuron, cintofen, ciobutide, cisanilide, cismethrin, clacifos, clefoxydim, clenpirin, clenpyrin, clethodim, climbazole, cliodinate, clodinafop, cloetocarb, clofencet, clofenotane, clofentezine, clofenvinphos, clofibric acid, clofop, clomazone, clomeprop, clonitralide, cloprop cloproxidim, clopyralide, cloquintocet, chloransulam, closantel, clothianidin, clotrimazole, cloxifonac, cloxilacon, clozilacon, CMA, CMMP, CMP, CMU, codlemona, cholecalciferol, colophonate, copper 8-quinolinolate, copper acetate, copper acetoarsenite, copper arsenate, copper carbonate, basic, copper hydroxide, copper naphthenate, copper oleate, copper oxychloride, copper silicatecobre sulphate, cobre sulphate, basic, copper zinc chromate, coumaclor, coumafeno, cicloprotrina, cimoxanilo, ciproconazol, ciprodón, cicyloide, cisogong, coumafos, coumafurilo, coumafos, coumatetralilo, coumetoxistrobína, coumitoato, coumoxistrobina, CPMC, CPMF, CPPC, crotoxifos, crufomate, cryolita, cuelure, cufraneb, cumileron, cumiluron, cuprobam, cuprous oxide, curcumenol, CVMP, cyanamide, cyanathrin, cyanazine, cyanofenfos, cyanógeno, cyanophos, cyanthoate, ciantraniliprol, cyanuric acid, ciazofamide, cibutrin, ciclafuramida, ciclanilida, ciclaniliprol, cyclethrin, cycloate, cycloheximida, cycloprate, cycloprothrin, cyclopyranil, cyclopyrimorate, cyclosulfamuron, cycloxidim, cicluron, cienopyrafen, ciflufenamid, ciflumethofen, cifluthrin, cihalodiamida, cihalofop, cihalothrin, cihexatin, cimiazol, cimoxanil, ciometrinil, cipendazol, cipermethrin, ciperquat, cyphenothrin, cyprazine, ciprazol, ciproconazol, ciprodinil, ciprofuram, cipromid, ciprosulfamida, cyromazine,citioato, citrex, daimurón, dalapón, daminozide, dayoutong, dazomet, DBCP, d-camphor, DCB, DCIP, DCPA (Japan), DCPA (US), DCPTA, DCU, ODD, DDPP, DDT, DDVP, debacarb, decafentin, decafentine, decarbohydrate, áethicido dehydroacetic acid, deiquat, delachlor, delnav, deltamethrin, demephion, demephion-O, demephion-S, demethone, demethone-methyl, demethone-O, demethone-O-methyl, demetone-S, demethone-S-methyl, demethone-SIF-2 Page 8 of 82 methyl sulfone, demeton-S-methylsulfone, DEP, depaletrin, derris, desmedipham, desmetnn, desmethrina, d-fanshiluquebingjuzhi, diafenturion, dialifor, dialifos, dialato, di-alato, diamidafos, dianat, diatomaceous earth, diatomite, diazinon, dibrom, dibutyl phthalate, dibutyl succinate, dicamba, dicafton, diclobenil, diclobenthiazox, diclofenthion, diclofluanide, dichlone, dichloralurea, dichlorbenzuron, dichlorphenidim, dichlorflurecol, dichlorflurenol, dichlormato, dichlormide, dichloromethane, dichlorophen, dichlorprop, dichlorprop-P, dichlorvos, diclozolin, diclozolina, diclobutrazol, diclocimet, diclofop, diclomezina, dichlorán, dichloromesothiaz, diclosulam, dicofol, dicofan, dicoumarol, dicresilo, dicrotophos, dicrilo, dicumarol, dicilanil, diciclonon, dieldrin, dienochlor, dietamquat, dietatil, dietion, dietion, dietofencarb, dietolato, dieton, diethyl pyrocarbonato, diethyltoluamide, difenacoum, difenoconazol, difenopenteno, difenoxurón, difenzoquat, difethialona, ​​diflovidazin, diflubenzurón, diflufenicán,diflufenicanil, diflufenzopyr, diflumetorim, dikegulac, dilor, dimatif, dimefluthrin, dimefox, dimefuron, dimehypo, dimepiperate, dimethaclon, dimethan, dimetacarb, dimethaclon, dimetachlor, dimetamethrin, dimethenamide, dimethenamide-P, dimethipin, dimethrimol, dimethoate, dimethomorph, dimethrin, dimethyl carbate, dimethyl disulfide, dimethyl phthalate, dimethylvinphos, dimethylan, dimexane, dimidazone, dimoxystrobin, dimpropyridaz, dimpilate, dimuron, dinex, dingjunezuo, diniconazole, diniconazole-M, dinitramine, dinitrophenols, dinobuton, dinocap, dinocap-4, dinocap-6, dinocton, dinophenate dinopenton, dinoprop, dinosam, dinoseb, dinosulfon, dinotefuran, dinoterb, dinoterbon, diophenolan, dioxabenzophos, dioxacarb, dioxathione, dioxathione, diphacin, diphacinone, dipenadione, dipenamide, dipenamide, diphenyl sulfone, diphenylamine, diphenylsulfide, diprogulic acid, dipropaline, dipropethrin, dipterex, dipimethitrone, dipyrithione, diquat, disodium tetraborate, disosultap, disparlure, disugran, disul, disulfiram,disulphoton, dithalymphos, dithionone, dithierbphos, dithioether, dithiometone, dithiopyrr, diuron, dixanthogen, d-limonene, DMDS, DMPA, DNOC, dodemorph, dodicine, dodine, dofenapin, doguadine, dominicalure, doramectin, Dzoxol, DPC, DSMA, trans-trans d-trans-resmethrin, dufulin, dimron, EBEP, EBP, ebufos, ecdysterone, eclomezole, EDB, EDC, EDDP, IF-2019-63795218-APN-ANP#INpI Page 9 of 82 edifenfos, eglinazine, emamectin, EMPC, empentaria, enadenine, endosulfan, endotal, endothion, endrin, enestroburin, enilconazole, enoxastrobin, efirsulfonate, EPN, epocoleone, epofenonan, epoxiconazole, eprinomectin, epronaz, epsilon-metofluthrine, epsilon-momfluorothrine, EPTC, erbon, ergocalciferol, erlujixiancaoan, esdépalléthrine, esfenvalerate, ESP, esprocarb, etacelasil, etaconazole, etafos, etem, etaboxam, etaclor, etalfluralin, etametsulfuron, etaprochlor, ethephon, etidimuron, etiofencarb, etiolate, ethion, etiozine, etiprol, etirimol ethoate-methyl, ethobenzanide, etofumesate, etohexadiol, ethoprop, ethoprophos, ethoxyfen, ethoxyquin, ethoxysulfuron, eticlozate, ethyl formate, ethyl pyrophosphate, ethylan, ethyl-DDD, ethylene, ethylene dibromide, ethylene dichloride, ethylene oxide, ethylicin, ethylmercury 2,3-dihydroxypropyl mercaptide, ethylmercury acetate, ethylmercury bromide, ethylmercuric chloride, ethylmercury phosphate, ethinophen, ETM, etnipromid, ethobenzanide, etofenprox,etoxazole, etridiazole, etrimfos, etrimphos, eugenol, EXD, famoxadone, famfur, fenac, fenamidone, fenaminosulf, fenaminstrobin, fehamifos, fenapanil, fenarimol, fenasulam, fenazaflor, fenazaquin, fenbuconazole, fenbutatin oxide, fenclorazole, fenclorfos, fenclofos, fenclorim, fenetacarb, fenfluthrin, fenfuran, fenhexamide, phenidine, fenitropan, fenitrothion, fenjuncton, fenobucarb, fenolovo, fenoprop, fenothiocarb, fenoxacrim, fenoxanil, fenoxaprop, fenoxaprop-P, fenoxasulfone, fenoxicarb, fenpiclonil, fenpicoxamide, fenpiritrin, fenpropathrin, fenpropidine, fenpropimorph, fenpyrazamine, fenpyroximate, fenquinotrione, fenridazone, fenson, fensulfothione, fenteracol, fentiaprop, fenthion, fenthion-ethyl, fentiaprop, fentin, fentrazamide, fentrifanil, fenuron, fenuron-TCA, fenvalerate, ferbam, ferimzone, ferric phosphate, ferrous sulfate, fipronil, flamprop, flamprop-M, flazasulfuron, flocoumafen, flometoquin, flonicamid, florasulam, florpyrauxifene, florylpicoxamide, fluacripyrim,fluazaindolizine, fluazifop, fluazifop-P, fluazinam, fluazolato, fluazuron, flubendiamide, flubenzimine, flubrocitrinato, flucarbazone, flucetosulfuron, fluchloralina, flucofuron, flucicloxuron, flucitrinato, fludioxonil, fluenethyl, fluenetil, fluensulfona, flufenacet, flufenerim, flufenican, flufenoxuron, flufenoxystrobin, flufenprox, flufenpir, flufenzine, flufiprole, fluhexafone, IF-2O19-63795218-APN-ANP#INPI Page 10 of 82 fluindapyr, flumethrin, flumetover, flumetraline, flumetsulam, flumezine, flumiclorac, flumioxazin, flumipropina, flumorf, fluometuron, fluopicolide, fluopimomide, fluopiram, fluorbenside, fluoridamide, fluoroacetamide, fluoroacetic acid, fluorochloridone, fluorodifen, fluoroglycofen, fluoroimide, fluoromide, fluoromidine, fluoronitrofen, fluoroxipyr, fluotiuron, fluotrimazole, fluoxapiproline, fluoxastrobin, flupoxam, flupropacil, flupropadine, flupropanate, flupiradifurone, flupirimine, flupyrsulfuron, fluquinconazole, fluranaler, flurazole, flurecol, flurenol, fluridone, flurocloridone, fluromidine, fluroxipyr, flurprimidol, flursulamide, flurtamon, flusilazole, flusulfamide, flutenzin, flutiacet, flutiamide, flutianil, flutriafol, fluvalinate, fluxametamide, fluxapiroxad, fluxfenim, folpel, folpet, falesafen, phonofos, foramsulfuron, forclorfenuron, formaldehyde, formethanate, formothion, formparanate, fosamine, fosetyl, fosmethylane, fospirate, fosthiazate, fostietan,frontalina, ftalida, fuberidazol, fucaojing, fucaomi, fujunmanzhi, fulumi, fumarina, funaihecaoling, fuphenthiourea, furalano, furalaxil, furametrina, furametpir, furano tebufenozida, furatiocarb, furcarbanil, furconazol, furconazol-c / sfuretrina, furfural, furilazol, furmeciclox, furofanato, furiloxifen, gamma-BHC, gamma-cihalotrina, gamma-HCH, genit, ácido giberélico, giberelina A3, giberelinas, gliftor, glitor, glucocloralosa, glufosinate, glufosinatoP, gliódina, glioxima, glifosato, glifosato, glifosina, gossyplure, grandlure, griseofulvina, guanoctina, guazatina, halacrinato, halauxifén, halfenprox, halofenozida, halosafén, halosulfurón, haloxidina, haloxifop, haloxifop-P, haloxifop-R, HCA, HCB, HCH, hemel, hempa, HEOD, heptaclor, heptaflutrina, heptenofos, heptopargil, herbimicina, herbimicina A, heterofos, hexaclor, hexaclorano, hexacloroacetona, hexaclorobenceno, hexaclorobutadieno, hexaclorofeno, hexaconazol, hexaflumurón, hexafluoramina, hexaflurato, hexalure, hexamida,hexazinone, hexylthiophos, hexitiazox, HHDN, holosulf, homobrasinolide, huancaiwo, huanchogjing, huangcaoling, huanjunzuo, hydramethylnon, hydrargaphene, hydrated lime, hydrogen cyanamide, hydrogen cyanide, hydroprenoxazole, hydroxyxazole, hydroxycarbonate, hym IAA, IBA, IBP, ¡candina, imazalilo, imazametabenz, imazamox, imazapic, imazapir, imazaquin, ¡mazetapir, imazosulfuron, imibenconazole, IF-2019-63795218-APN-ANP#iNPi Page 11 of 82 imiciafos, imidacloprid, imidaclotiz, iminoctadine, imiprotrine, inabenfide, indanofan, indaziflam, indoxacarb, inezine, infusory earth, inpirfluxam, iodobonil, iodocarb, iodomethane, iodomethane, iodosulfuron, ioxinil, ipazine, IPC, ipconazole, ipfencarbazone, ipfentrifluconazole, ipflufenoquine, iprobenphos, iprodione, iprovalicarb, iprimidam, ipsdienol, ipsenol, IPSP, IPX, isamidophos, isazophos, isobenzane, isocarbamide, isocarbamide, isocarbophos, isocyl, isocloseram, isodrin, isofenphos, isofenphos-methyl, isofetamide, isoflucipram, isolan, isothiozine, isonoruron, isopamphos, isopolinate, isoprocarb, isoprocyl, isopropaline, isopropazole, isoprotiolane, isoproturon, isopyrazam, isopyrimol, isothioate, isothianil, isourone, isovaledione, isoxaben, isoxachlortol, isoxadiphen, isoxaflutol, isoxapyrifop, isoxathion, isuron, ivermectin, ixoxaben, isopamphos, japonilure, japotrins, jasmolin I, jasmolin II, jasmonic acid, Jiahuangchongzong, Jiajizengxiaolin, Jiaxiangjunzhi, Jiecaowan,jiecaoxi Jinganmycin A, iodofenphos, juvenile hormone I, juvenile hormone II, juvenile hormone III, cadethrin, kappa-bifenthrin, kappa-tefluthrine, carbutylate, karetazán, kasugamycin, kejunlin, kelevan, ketospiradox, kieselguhr, kinetin, quinoxyl, chyroxime, cresomethyl, methyl kuicaoxi, lactofen, / ambda-cihalothrin, lancotrione, latilure, lead arsenate, lenacyl, lepimectin, leptofos, lianbenjingzhi, lime sulfur, lindane, lineatin, linurón, lirimfos, litlure, looplure, lotilaner, lufenuron, lufen, fuqonan, lyuxiancaolin, Ivdingjunzhi, Ivfumijvzhi, Ivxiancaolin, lythidathion, M-74, M-81, MAA, magnesium phosphide, malathion, maldison, maleic hydrazide, malonoben, maltodextrin, MAMA, mancobre, mancozeb, mandestrobina, matripamine, matripamine, matrib mazidox, MCC, MCP, MCPA, MCPA-thioethyl, MCPB, MCPP, mebenyl, mecarbam, mecarbinzide, mecarfón, mecoprop, mecoprop-P, medimeform, medinoterb, medlure, mefenacet, mefenoxam, mefenpyr, mefentride, mefluidic acid, megafluid, megatomozoic acidmelisyl alcohol, melitoxin, MEMC, menazón, MEP, mepanipirim, meperfluthrin, mefenate, mesfosfolan, mepiquat, mepronil, meptildinocap, mercaptodimetur, mercaptofos, mercaptophos thiol, mercaptotion, mercuric chloride, mercurous chloride, merfos, merphos oxide, mesoprazine, mesosulfuron, mesotrione, mesulfen, mesulfenfos, mesulfene, metacresol, IF-2O19-63795218-APN-ANP#INPI Page 12 of 82 metaflumizone, metalaxyl, metalaxyl-M, metaldehyde, metam, metamifop, metamitron, metafos, metaxon, metazachlor, metazosulfuron, metazoxolon, metcamifen, metconazole, metepaz, metflurazon, metabenzthiazure, methacryphos, metalpropaline, metam, methamidophos, metasulfocarb, metazole, metfuroxam, methibenzuron, methidathion, methiobencarb, methiocarb, methiopyrisulfuron, methiotepa, methiazoline, methiuron, metocrotophos, metholcarb, methometon, methomyl, methoprene, metoprotrin, metoprotrin, metoquin-butyl, methotrine, methoxychlor, methoxyfenozide, methoxyphenone, methyl afolate, methyl bromide, methyl eugenol, methyl iodide methyl isothiocyanate, methyl parathion, methylacetophos, methyl chloroform, methyldithiocarbamic acid, methyldimron, methylene chloride, methylisofenphos, methylmercaptophos, methylmercaptophos oxide, methylmercaptophos thiol, methylmercury benzoate, methylmercury dicyanamide, methylmercury pentachlorophenoxide, methylneodecanamide, methylnitrophos, methyltriazothion, methiazolinemetiram, metiram-zinc, methobenzuron, methobromuron, methofluthrin, metolachlor, metholcarb, methomethuron, methominostrobin, methosulam, methoxadiazone, methoxuron, metraphenone, metriam, metribuzine, metrifonate, metrifonate, metsulfovax, metsulfuron, methyltetraprol, mevinfos, mexacarbate, miechuwei, mieshuan, miewenjuzhi, milbemectin, milbemycin oxime, milneb, mimanan, mipafox, MIPC, mirex, MNAF, moguchun, molinate, molosultap, momfluorothrin, monalide, monisuron, monoamitraz, monochloroacetic acid, monocrotophos, monolinuron, monomehypo, monosulfiram, monosulfuron, monosultap, monuron, monuron-TCA, morfamquat, moroxidine, morphothion, morzid, moxidectin, MPMC, MSMA, MTMC, muscalure, myclobutanil, myclozolin, myricyl alcohol, N(ethylmercury)-p-toluenesulfonanilide, NAA, NAAm, nabam, naphthalophos, naled, naphthalene, naphthaleneacetamide, naphthalic anhydride, naphthalophos, naphthoxyacetic acids, naphthylacetic acids, naphthylindane-1,3-diones, naphthyloxyacetic acids, naproanilide, napropamide,napropamide-M, naptalam, natamicina, NBPOS, neburea, neburón, nendrin, neonicotine, nichlorfos, niclofen, niclosamide, nicobifén, nicosulfuron, nicotine, nicotine sulfate, nifluridide, nikomycins, NIP, nipiraclofen, nipiralofen, nitenpyram, nithiazine, nitraline, IF-2019-63795218-APN-ANP#INPI Page 13 of 82 nitrapirina, nitrilacarb, nitrofén, nitrofluorfén, nitrostireno, nitrotal-isoprolil, nobormida, nonanol, norbormida, norflurazón, nornicotina, norurón, novalurón, noviflumurón, NPA, nuarimol, nuranona, OCH, octaclorodipropil éter, octilinona, o-diclorobenceno, ofurace, ometoato, o-fenilfenol, orbencarb, orfralure, ortobencarb, orto-diclorobenceno, ortosulfamurón, orictalure, orisastrobina, orizalina, osthol, osthole, ostramona, ovatron, ovex, oxabetrinilo, oxadiargilo, oxadiazon, oxadixilo, oxamato, oxamilo, oxapirazón, oxapirazón, oxasulfurón, oxatiapiprolina, oxaciclomefona, oxazosulfilo, oxinato de cobre, oxinato-Cu, ácido oxolinico, oxpoconazol, oxicarboxina, oxidemeton-metil, oxideprofos, oxidisulfotón, oxienadenina, oxifluorfén, oximatrina, oxitetraciclina, oxitioquinox, PAC, paclobutrazol, paichongding, palléthrine, PAP, para-diclorobenceno, paraflurón, paraquat, paratión, paratión-metil, parinol, verde Paris, PCNB, PCP, PCP-Na, p-diclorobenceno, PDJ, pebulato, pédinex,pefurazoate, ácido pelargónico, penconazol, pencicurón, pendimethalin, penfenato, penflufén, penflurón, penoxalina, penoxsulam, pentaclorofenol, pentaclorofenil laurato, pentanoclor, pentiopirad, pentmetrina, pentoxazona, perclordecona, perfluidona, permetrina, pentoxamide, PHC, fenamacril, fenamacril-etil, phénaminosulf, fenazine óxido, phénétacarbe, fenisofam, fenkaptón, fenmedifam, fenmedifam-etil, fenobenzuron, fenotiol, fenotrina, fenpróxido, fentoato, fenilmercuriurea, acetato de fenilmercurio, cloruro de phenylmercury, pyrocatechol phenylmercury derivative, phenylmercury nitrate, phenylmercury salicylate, phorate, fosacetim, fosalona, ​​fosametin, fosazetim, fosazetin, fosciclotin, fosdifén, fosetil, fosfolán, phospholán-methyl, phosglycine, phosmet, fosniclor, phosfamida, phosphamidón, phosphine, phosphinothricin, phosphocarb, phosphorus, fostin, foxim, foxim-methyl, phtalida, phthalofos, phthalthrin, picarbutrazox, picaridin, picloram, picolinafén, picoxistrobin, pimaricin, pindona,pinoxaden, piperalina, piperazina, piperonil butóxido, piperonil cicloneno, piperofos, piproctanil, piproctanil, piprotal, pirimetafos, pirimicarb, piriminil, pirimioxifos, pirimifos-etil, pirimifos-etil, pirimifosmetil, pival, pivaldiona, plifenato, PMA, PMP, polibutenos, policarbamato, policlorcamfeno, polietoxiquinolina, polioxina D, polioxinas, polioxorim, politialán, arsenito de potasio, azida, IF-2019-63795218-APN-ANP#INPI Página 14 de 82 potassium, potassium cyanate, potassium ethylxanthate, potassium naphthenate, potassium polysulfide, potassium thiocyanate, pp'-DDT, praletrin, precocene I, precocene II, precocene III, pretilachlor, primidofos, primisulfuron, probenazol, procloraz, proclonol, procyazine, procymidona, prodiamine, profenofos, profluazol, profluralina, proflutrin, profoxidim, profurite-aminium, proglinazine, prohexadiona, prohidrojasmon, promacilo, promecarb, prometon, prometrin, prometrine, promurit, pronamida, pronitridine, propachlor, propafos, propamidine, propamocarb, propanil, propafos, propaquizafop, propargita, propartrina, propazine, propetamfos, profam, propiconazol, propidine, propineb, propisochlor, propoxur, propoxycarbazona, propilisoma, propirsulfurón, propizamida, proquinazid, prosuler, prosulfalin, prosulfocarb, prosulfurón, protidatión, protiocarb, protioconazol, protiofos, protoato, protrifenbute, proxan, primidofos, prinaclor, psoralen, psoralen, pidanón, pidiflumetofen, piflubumida,pymetrozine, piracarbolid, pyraclofos, pyraclonil, pyraclostrobin, pyraflufen, pyrafluprole, piramat, pyrametostrobin, pyraoxystrobin, pyrapropoyne, pirasulfotole, pyraziflumid, pyrazolate, pyrazolinate, pyrazon, pyrazophos, pyrazosulfuron, pyrazothion, pyrazoxifen, pyresmethrin, Python pyriftalida, pyrimétaphos, pyrimethanil, pirimicarb, pirimidifen, piriminobac, piriminostrobin, pirimiphos-éthyl, pyrimiphos-méthyl, pirimisulfan, pirimitate, pyrinuron, pyriofenone, pyriprol, pyripropanol, pyriproxifen, pyrisoxazole, pyrithiobac, pyrolan, piroquilon, pyroxasulfone, piroxsulam, piroxiclor, piroxifur, quincaosuan, qingkuling, quassia, quinacetol, quinalfos, quinalfos-methyl, quinazamide, quinclorac, quinconazole, quinmerac, quinoclamine,quinofumelina, quinomethionato, quinonamida, quinotion, quinoxifen, quintiofos, quintozeno, quizalofop, quizalofop-P, quwenzhi, quyingding, rabenzazol, rafoxanida, R-diniconazol, rebemida, reglone, renridurón, rescalure, resmetrina, rodetanil, rodojaponin-lll, ribavirin, rimsulfurón, rizazol, R-metalaxil, rodéthanil, ronnel, rotenona, riania, sabadilla, saflufenacil, saijunmao, IF-2019-63795218-APN-ANP#INPI Página 15 de 82 saisentong, salicilanilida, salifluofén, sanguinarina, santonina, S-bioaletrina, schradan, escilirósido, sebutilazine, secbumetón, sedaxano, selamectina, semiamitraz, sesamex, sesamolina, sesona, setoxidim, sevin, shuangjiaancaolin, shuangjianancaolin, Shidropreno, sidurón, sifumijvzhi, siglure, silafluofén, silatrano, aerogel de sílice, gel de sílice, siltiofam, siltiofam, siltiofan, silvex, simazina, simeconazol, simetón, simetrin, simetrina, sintofén, S-kinopreno, cal hidratada, SMA, S-metoprene, S-metolachlor, sodium arsenite, sodium azide, sodium chlorate, sodium cyanide, sodium fluoride, sodium fluoroacetate, sodium hexafluorosilicate, sodium naphthenate, sodium o-phenylphenoxide, sodium orthophenylphenoxide, sodium pentachlorophenate, sodium pentachlorophenoxide, sodium polysulfide, sodium silicofluoride, sodium tetrathiocarbonate, sodium thiocyanate, solan, sofamida, spinetoram, spinosad, spirodiclofen, spiromesifen, spiropidion, spirotetramat,spiroxamina, stirofos, estreptomicina, estricnina, sulcatol, sulcofuron, sulcotriona, sulfalato, sulfentrazona, sulfiram, sulfluramid, sulfodiazol, sulfometuron, sulfosato, sulfosulfuron, sulfotep, sulfotepp, sulfoxaflor, sulfóxido, sulfoxima, azufre, ácido sulfúrico, fluoruro de sulfurilo, sulglicapin, sulfosato, sulprofos, sultropen, swep, taufluvalinato, tavron, tazimearb, TBTO, TBZ, TCA, TCBA, TCMTB, TCNB, TDE, tebuconazol, tebufenozida, tebufenpirad, tebufloquin, tebupirimfos, tebutam, tebutiuron, tecloftalam, tecnazeno, tecoram, tedion, teflubenzuron, teflutrina, tefuriltriona, tembotriona, temefos, temefos, tepa, TEPP, tepraloxidim, teproloxidim, teraletrina, terbacil, terbucarb, terbuclor, terbufos, terbumeton, terbutilazina, terbutol, terbutrin, terbutrina, terraclor, terramicin, terramycin, tetciclacis, tetflupirolimet, tetracloroantraniliprol, tetracloroetano, tetraclorvinfos, tetraconazol, tetradifon, tetradisul, tetrafluron, tetrametrina, tetrametiloflutrina, tetramina,tetranactin, tetraniliprol, tetrapion, tetrasul, thallium sulfate, thallium sulfate, tenylchlor, cypermethrin, thiabendazole, thiacloprid, thiadiazine, thiadifluor, thiamethoxam, thiameturon, tiapronil, thiazafluron, thiazopyr, ticrofos, ticiofen, tidiazimin, tidiazuron, thiencarbazone, tifensulfuron, tifluzamide, thimerosal, thimethoxam, thiocarboxymethylcellulose, thiochlorfenfin, thiochlorfenfin IF-2019-63795218-APN-ANP#iNPi Page 16 of 82 thiocyanadinitrobenzenes, thiocyclam, thiodan, thiodiazole-copper, thiodicarb, thiophanocarb, thiofanox, thiofluoximate, thiohempa, thiomersal, thiometon, thionazine, thiophanate, thiophanate-ethyl, thiophanate-methyl, thiophos, thioquinox, thiosemicarbazide, thiosultap, thiotepa, thioxamyl, thiram, thiuram, thuringiensin, thiabendazole, tiadinil, thiafenacil, tiaojian, TIBA, tifatol, thiocarbacil, thioclorim, thioxazafen, thioximid, tirpate, TMTD, tolclofos-methyl, tolfenpyrad, tolprocarb, tolpyralate, tolifluanid, tolylfluanid, tolylmercury acetate, tomarine, topramezone, toxaphene, TPN, tralcoxydim, tralocitrin, tralometrine, tralopyril, transfluthrin, transpermethrin, tretamine, triacontanol, triadimefon, triadimenol, triafamone, trialate, trialate, triamiphos, triapentenol, triaratene, triarimol, triasulfuron, triazamate, triazbutyl, triaziflam, triazofos, triazothion, triazoxide, tribasic copper chloride, tribasic copper sulfate, tribenuron, tributos, tributyltin oxide, tricamba, triclamidetriclopir, triclorfon, triclormetafos-3, tricloronat, tricloronato, triclorotrinitrobencenos, triclorfon, triclopir, triclopiricarb, tricresol, triciclazol, hidróxido de triciclohexiltin, tridemorf, tridifano, trietazina, trifenmorf, trifenofos, trifloxlstrobina, trifloxisulfuron, trifludimoxazin, triflumezopirim, triflumizol, triflumuron, trifluralin, triflusulfuron, trifop, trifopsina, triforina, trihidroxitriazina, trimediur, trimetacarb, trimeturon, trinexapac, trifeniltin, tripreno, tripropindan, triptolida, tritac, tritialan, triticonazol, tritosulfuron, trunc-call, tuoyelin, ticiclopirazoflor, uniconazol, uniconazol-P, urbacida, uredepa, valerato, validamicina, validamicina A, valifeñalato, valona, vamidotion, vangard, vaniliprol, vernolato, vinclozolln, vitamina D3, warfarina, xiaochongliulin, xinjunan, xiwojunan, xiwojunzhi, XMC, xilaclor, xilenoles, xililcarb, ximiazol, yishijing, zarilamid, zeatin, zengxiaoan, zengxiaolin, zetacipermetrina, naftenato de zinc,zinc phosphide, zinc thiazole, zinc thiazole, zinc trichlorophenate, zinc trichlorophenoxide, zineb, ziram, zolaprofos, zoocoumarin, zoxamide, zuoanjunzhi, zuocaoan, zuojunzhi, zuomihuanglong, a-chlorohldrin, α-ecdysone, ccmultistriatin, α-naphthaleneacetic acids, and β-ecdysone; (2) the following molecules in Table 1 IF-2019-63795218-APN-ANP#INPI Page 17 of 82 As used in this description, each of the above is an active ingredient. For more information, consult the materials listed in the Compendium of Pesticide Common Names found at Alanwood.net and various editions. IF-2019-63795218-APN-ANP#INRI Page 18 of 82. .> which include the online edition of “The Pesticide Manual” found at bcpcdata.com. A particularly preferred selection of the active ingredients are 1,3 dichloropropene, chlorantraniliprole, chlorpyrifos, cyantraniliprole, hexaflumuron, methomyl, methoxyfenozide, noviflumuron, oxamyl, spinetoram, spinosad, sulfoxaflor and triflumezopyrim (hereafter referred to as “AIGA-2”). In addition, another particularly preferred selection of active ingredients are acequinocyl, acetamiprid, acetoprole, avermectin, azinphos-methyl, bifenazate, bifenthrin, carbaryl, carbofuran, chlorfenapyr, chlorfluazuron, chromafenozide, clothianidin, cyfluthrin, cypermethrin, deltamethrin, diafenthiuron, emamectin benzoate, endosulfan, esfenvalerate, etiprol, etoxazole, fipronil, flonicamid, fluacripyrim, gamma-cyhalothrin, halofenozide, indoxacarb, ambda-cyhalothrin, lufenuron, malathion, methomyl, novaluron, permethrin, pyridalyl, pirimidifen, spirodiclofen, tebufenozide, thiacloprid, thiamethoxam, thiodicarb, tolfenpyrad, and zefa-cypermethrin (hereinafter “AIGA-3”). The term “biopesticide” refers to a microbial biological control agent that is generally applied in a similar way to chemical pesticides. They are commonly bacterial, but examples also include fungal control agents such as Trichoderma spp. and Ampelomyces quisqualis. A well-known example of a biopesticide is Bacillus spp., a bacterial agent that controls diseases of Lepidoptera, Coleoptera, and Diptera. Biopesticides include products based on entomopathogenic fungi (e.g., Metarhizium anisopliae), entomopathogenic nematodes (e.g., Steinernema feltiae), and entomopathogenic viruses (e.g., granulovirus Cydia pomonella). Other examples of entomopathogenic organisms include, but are not limited to, baculoviruses, protozoa, and microsporidia. To avoid confusion, biopesticides are active ingredients. The term “locus” means a habitat, breeding site, plant, seed, soil, material, or environment in which a pest is growing, can grow, or can migrate. IF-2019-63795218-APN-ANP#INPI Page 19 of 82 For example, a locus can be: where crops, trees, fruits, cereals, forage species, vines, grass and / or ornamental plants are growing; where domesticated animals reside; the interior or exterior surfaces of buildings (such as places where grains are stored); the building materials used in buildings (such as impregnated wood); and the soil around buildings. The phrase “Material MoA” refers to an active ingredient that has a mode of action (“MoA”) as indicated in the IRAC MoA Classification v. 8.3, which can be found at irac-online.org, which describes the following groups. (1) Acetylcholinesterase (AChE) inhibitors, including the following active ingredients: alanicarb, aldicarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, etiofencarb, fenobucarb, formetanate, furatiocarb, isoprocarb, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiophanox, triazamate, trimetacarb, XMC, xylylcarb, acetate, azamethiphos, azinphos-ethyl, azinphos-methyl, cadusafos, chlorethoxyphos, chlorfenvinphos, chlormephos, chlorpyrifos, chlorpyrifos-methyl, coumaphos, cyanophos, demeton-S-methyl, diazinon, dichlorvos / DDVP, dicrotophos, dimethoate, dimethylvinphos, disulfoton, EPN, ethion, ethoprophos, famfur, fenamiphos, fenitrothion, fenthion, fostiazate, heptenofos, isofenphos, isoxation, malathion, mecarbam, metamidophos, metidathion, mevinphos, monocrotophos, naled, omethoate, oxidemeton-methyl, parathion, parathion-methyl, pentoate, phosalone, phorate, phosmet, fosfamidon, phoxim, profenophos, propetamphos, prothiofos, pyraclofos, pyridafenthion,quinalfos, sulfotep, tebupirimphos, temefos, terbufos, tetrachlorvinphos, thiometon, triazophos, trichlorfon, vamidothion, pirimifos-methyl, imiciafos and isopropyl O-(methoxyaminothio-phosphoryl) salicylate. (2) GABA-dependent chloride channel antagonists include the following active ingredients: chlordane, endosulfan, etiprol, and fipronil. (3) Sodium channel modulators include the following active ingredients: acrinathrin, allethrin, d-cis-trans allethrin, d-trans allethrin, bifenthrin, bioallethrin, bioallethrin S-cyclopentenyl, bioresmethrin, cycloprothrin, cyfluthrin, beta- IF-2019-63795218-APN-ANP#iNPI Page 20 of 82 cyfluthrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyfenothrin [(IR)-trans- isomers], deltamethrin, empentrin [(EZ)-(1R)- isomers], esfenvalerate, etofenprox, fenpropathrin, fenvalerate, flucythrinate, flumethrin, tau-fluvalinate, kadethrin, pyrethrins (pyrethrum), halfenprox, phenothrin [(IR)-trans- isomer], prallethrin, resmethrin, silafluofen, tefluthrin, tetramethrin, tetramethrin [(1R)- isomers], tralomethrin, transfluthrin, permethrin, DDT and methoxychlor. (4) Nicotinic acetylcholine receptor (nAChR) agonists include the following active ingredients: (4A) acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam, (4B) nicotine, (4C) sulfoxaflor, (4D) flupyradifurone, and (4E) triflumezopyrim. (5) Allosteric activators of nicotinic acetylcholine receptors (nAChR) include the following active ingredients: spinetoram and spinosad. (6) Chloride channel activators include the following active ingredients: abamectin, emamectin benzoate, lepimectin, and milbemectin. (7) Juvenile hormone mimetics include the following active ingredients: hydroprene, kinoprene, methoprene, phenoxycarb, and pyriproxyfen. (8) Miscellaneous non-specific (multi-site) inhibitors include the following active ingredients: methyl bromide, chloropicrin, cryolite, sulfuryl fluoride, borax, boric acid, disodium octaborate, sodium borate, sodium metaborate, tartar emetic, diazomet, and metam. IF-2019-63795218-APN-ANP#INPI Page 21 of 82 (9) The modulators of the TRPV channels of the chordotonal organs include the following active ingredients: aphidopyropen, pymetrozine, and pyrifluquinazon. (10) Mite growth inhibitors include the following active ingredients: clofentezine, hexythiazox, diflovidazine, and etoxazole. (11) Microbial disruptors of insect midgut membranes include the following active ingredients: Bt var. israelensis, Bt var. aizawai, Bt var. kurstaki, Bt var. tenebrionensis and Bacillus sphaericus. (12) Mitochondrial ATP synthase inhibitors include the following active ingredients: tetradifon, propargite, azocyclotin, cyhexatine, fenbutatine oxide, and 10-diaphenthiuron. (13) Uncouplers of oxidative phosphorylation by interrupting the proton gradient include the following active ingredients: chlorfenapyr, DNOC, and sulfluramide. (14) Nicotinic acetylcholine receptor (nAChR) channel blockers include the following active ingredients: bensultap, cartap hydrochloride, thiocyclam, and thiosultap-sodium. (15) Chitin biosynthesis inhibitors, type 0, include the following active ingredients: bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron and 20 triflumuron. (16) Chitin biosynthesis inhibitors, type 1, include the following active ingredient buprofezin. (17) Molting disruptors, Diptera, include the following active ingredient cyromazine. (18) Ecdysone receptor agonists include the following active ingredients: chromafenozide, halofenozide, methoxyfenozide, and tebufenozide. IF-2019-63795218-APN-ANP#iNPi Page 22 of 82 (19) Octopamine receptor agonists include the following active ingredient: amitraz. (20) Mitochondrial complex III electron transport inhibitors include the following active ingredients: hydramethylnon, acequinocil, 5 bifenazate, and fluacripyrim. (21) Mitochondrial complex I electron transport inhibitors include the following active ingredients: phenazaquine, fenpyroximate, pirimidifene, pyridaben, tebufenpyrad, tolfenpyrad, and rotenone. (22) Voltage-gated sodium channel blockers, 10 include the following active ingredients indoxacarb and metaflumizone. (23) Acetyl CoA carboxylase inhibitors include the following active ingredients: spirodiclofen, spiromesifen, and spirotetramat. (24) Mitochondrial complex IV electron transport inhibitors include the following active ingredients: aluminum phosphide, calcium phosphide, phosphine, zinc phosphide, and cyanide. (25) Mitochondrial complex II electron transport inhibitors include the following active ingredients: cyenopirafene, cyflumethofen, and piflubumide. (28) Ryanodine receptor modulators include the following active ingredients: chlorantraniliprole, cyantraniliprole, and flubendiamide. (29) Modulators of the chordotonal organs - target site undefined, include the following active ingredient flonicamid. Groups 26 and 27 have no assignments in this version of the classification scheme. Additionally, there is a UN Group containing active ingredients with an unknown or undetermined mode of action. This group includes the following 25 active ingredients: azadirachtin, benzoximate, bromopropylate, quinomethionate, dicofol, GS-omega / kappa peptide HXTX-Hv1a, calcium polysulfide, pyridalyl, and sulfur. IF-2019-63795218-APN-ANP#INPI Page 23 of 82 The term “pest” refers to an organism that is harmful to humans, or of concern to humans (such as crops, food, livestock, etc.), where said organism belongs to the phyla Arthropoda, Mollusca, or Nematoda. Specific examples include ants, aphids, bed bugs, beetles, springtails, caterpillars, cockroaches, crickets, earwigs, fleas, flies, grasshoppers, larvae, hornets, killer bees, cicadas, lice, locusts, worms, mites, moths, nematodes, leafhoppers, psyllids, sawflies, scale insects, silverfish, slugs, snails, spiders, springtails, stink bugs, symphylans, termites, spider mites, ticks, wasps, whiteflies, and elaterids. Additional examples are pests in (1) Subphylum Chelicerata, Myriapoda and Hexapoda (2) Classes Arachnida, Symftla, and Insecta. (3) Order Anoplura. A non-exhaustive list of particular genera includes, but is not limited to, Haematopinus spp., Hoplopleura spp., Linognathus spp., Pediculus spp., Polyplax spp., Solenopotes spp., and Neohaematopinis spp. A non-exhaustive list of particular species includes, but is not limited to, Haematopinus asini, Haematopinus suis, Linognathus setosus, Linognathus ovillus, Pediculus humanus capitis, Pediculus humanus humanus, and Pthirus pubis. (4) Order Coleoptera. A non-exhaustive list of particular genera includes, but is not limited to, Acanthoscelides spp., Agrietes spp., Anthonomus spp., Apion spp., Apogonia spp., Araecerus spp., Aulacofora spp., Bruchus spp., Cerosterna spp., Cerotoma spp., Ceutorhynchus spp., Chaetocnema spp., Colaspis spp., Ctenicera spp., Curculio spp., Ciclocephala spp., Diabrotica spp., Dinoderus spp., Gnathocerus spp., Hemicoelus spp., Heterobostruchus spp., Hypera spp., Ips spp., Lyctus spp., Megascelis spp., Meligethes spp., Mezium spp., Niptus spp., Otiorhynchus spp., Pantomorus spp., Phillophaga spp., Phillotreta spp., Ptinus spp., Rhizotrogus spp., Rhynchites spp., Rhynchoforus spp., Scolytus spp., Sfenoforus spp., Sitophilus spp., Tenebno spp., y IF-2019-63795218-APN-ANP#INPI Page 24 of 82 .. TriboHum spp. A non-exhaustive list of particular genera includes, but is not limited to, Acanthoscelides obtectus, Agrilus planipennis, Ahasverus advena, Alphitobius diaperinus, Anoplophora glabripennis, Anthonomus grandis, Anthrenus verbasci, Anthrenus faivipes, Ataenius spretulus, Atomaria linearis, Attagenus unicolor, Bothynoderes punctiventris, Bruchus pisorum, Callosobruchus maculatus, Carpophilus hemipterus, Cassida vittata, Cathartus quadricollis, Cerotoma trifurcata, Ceutorhynchus assimilis, Ceutorhynchus napi, Conoderus scalaris, Conoderus stigmosus, Conotrachelus nenuphar, Cotinis nítida, Crioceris asparagi, Cryptolestes ferrugineus, Cryptolestes pusillus, Cryptolestes turcicus, Cilindrocopturus adspersus, Deporaus marginatus, Dermestes lardarius, Dermestes maculatus, Epilachna varivestis, Euvrilletta peltata, Faustinus cubae, Hilobius pales, Hilotrupes bajulus, Hypera postica, Hypothenemus hampei, Lasioderma serricorne, Leptinotarsa ​​decemlineata, Limonius canus,Liogenys fuscus, Liogenys suturalis, Lissorhoptrus oryzophilus, Lophocateres pusillus, Lyctus planicollis, Maecolaspis joliveti, Melanotus communis, Meligethes aeneus, Melolontha melolontha, Necrobia rufipes, Oberea brevis, Oberea linearis, Oryctes rhinoceros, Oryzaephilus mercator, Oryzaephilus surinamensis, Oulema melanopus, Oulema oryzae, Phyllophaga cuyabana, Polycaon stoutti, Pophlia japonica, Prostephanus truncatus, Rhyzopertha dominica, Sitona lineatus, Sitophilus granarias, Sitophilus oryzae, Sitophilus zeamais, Stegobium paniceum, Tenebroides mauritanicus, Tribolium castaneum, Tribolium confusum, Trogoderma granarium, Trogoderma variabile, Xestobium rufovillosum, and Zabrus tenebrioides., (5) Order Dermaptera. A non-exhaustive list of particular species includes, but is not limited to, Forficula auricularia. (6) Order Blattaria. A non-exhaustive list of particular species includes, but is not limited to, Blattella germanica, Blattella asahinai, Blatta orientalis, Blatta lateralis, Parcoblatta pennsilvanica, Periplaneta americana, Periplaneta australasiae, Periplaneta brunnea, Periplaneta fuliginosa, Pycnoscelus surinamensis, and Supella longipalpa. IF-2019-63795218-APN-ANP#INPI Page 25 of 82 (7) Order Diptera. A non-exhaustive list of particular genera includes, but is not limited to, Aedes spp., Agromyza spp., Anastrepha spp., Anopheles spp., Bactrocera spp., Ceratitis spp., Chrysops spp., Cochliomyia spp., Contarinia spp., Culex spp., Culicoides spp., Dasineura spp., Delia spp., Drosophila spp., Fannia spp., Hilemya spp., Liriomyza spp., Musca spp., Forbia spp., Pollenia spp., Psychoda spp., Simulium spp., Tabanus spp., and Tipula spp.A non-exhaustive list of particular species includes, but is not limited to, Agromyza frontella, Anastrepha suspensa, Anastrepha ludens, Anastrepha obliqua, Bactrocera cucurbitae, Bactrocera dorsalis, Bactrocera invadens, Bactrocera zonata, Ceratitis capitata, Dasineura brassicae, Delia platura, Fannia canicularis, Fannia scalas, Gasterophilus intestinalis, GraciHia perseae, Haematobia irritans, Hypoderma lineatum, Liriomyza brassicae, Liriomyza sativa, Melophagus ovinus, Musca autumnalis, Musca domestica, Oestrus ovis, Oscinella frit, Pegomya betae, Piophila casei, Psila rosae, Rhagoletis cerasi, Rhagoletis pomonella, Rhagoletis mendax, Sitodiplosis mosellana, and Stomoxis calcitrans. (8) Order Hemiptera. A non-exhaustive list of particular genera includes, but is not limited to, Adelges spp., Aulacaspis spp., Aphrofora spp., Aphis spp., Bemisia spp., Ceroplastes spp., Chionaspis spp., Chrysomphalus spp., Coccus spp., Empoasca spp., Euschistus spp., Lepidosaphes spp., Lagynotomus spp., Lygus spp., Macrosiphum spp., Nefotettix spp., Nezara spp., Nilaparvata spp., Philaenus spp., Phytocoris spp., Piezodorus spp., Pianococcus spp., Pseudococcus spp., Rhopalosiphum spp., Saissetia spp., Therioaphis spp., Toumeyella spp., Toxoptera spp., Trialeurodes spp., Triatoma spp., and Unaspis spp.A non-exhaustive list of particular species includes, but is not limited to, Acrosternum hilare, Acyrthosiphon pisum, Aleyrodes proletella, Aleurodicus dispersus, Aleurothrixus floccosus, Amrasca biguttula biguttula, Aonidiella aurantii, Aphis fabae, Aphis gossypii, Aphis glycines, Aphis pomi, Aulacorthum solani, Bactericera cockerelli, Bagrada hilaris, Bemisia argentifolii, Bemisia tabaci, Blissus leucopterus, Boisea trívittata, Brachycorynella asparagi, Brevennia rehi, Brevicoryne. IF-2019-63795218-APN-ANP#iNPI Page 26 of 82 brassicae, Cacopsylla pyri, Cacopsylla pyricola, Calocoris norvegicus, Ceroplastes rubens, Cimex hemipterus, Cimex lectularius, Coccus pseudomagnoliarum, Dagbertus fasciatus, Dichelops furcatus, Diuraphis noxia, Diaphorina citri, Dysaphis plantaginea, Dysdercus suturellus, Edessa meditabunda, Empoasca vitis, Eriosoma lanigerum, Erythroneura elegantula, Eurygaster maura, Euschistus conspersus, Euschistus heros, Euschistus servus, Halyomorpha halys, Helopeltis antonii, Hyalopterus pruni, Helopeltis antonii, Helopeltis theivora, Icerya purchasi, Idioscopus nitidulus, Jacobiasca formosana, Laodelphax striatellus, Lecanium corni, Leptocorisa oratorius, Leptocorisa varicornis,Lygus hesperus,Maconellicoccus hirsutus, Macrosiphum euphorbiae,Macrosiphum granarium, Macrosiphum rosae, Macrosteles quadrilineatus, Mahanarva frimbiolata, Megacopta cobraria, Metopolophium dirhodum, Mictis longicornis, Myzus persicae, Nasonovia, blackcurrant, Nephotettix cincticeps.Neurocolpus longirostris, Nezara viridula, Nilaparvata lugens, Paracoccus, marginatus. Paratrioza cockerelli, Parlatoria pergandii. Parlatoria ziziphi, Peregrinus maidis, Phylloxera vitifoliae, Physokermes piceae, Phytocoris californicus, Phytocoris relatives, Piezodorus guildinii, Pianococcus citri, Pianococcus ficus, Poecilocapsus lineatus, Psallus vaccinicola, Pseudacysta perseae, Pseudococcus brevipes, Quadraspidiotus perniciosus, Rhopalosiphum maidis, Rhopalosiphum padi, Saissetia oleae, Scaptocoris castanea, Schizaphis graminum, Sitobion avenae, Sogatella furcifera, Trialeurodes vaporariorum, Trialeurodes abutiloneus, Unaspis yanonensis and Zulia interbreed. (9) Order Hymenoptera. A non-exhaustive list of particular genera includes, but is not limited to, Acromyrmex spp., Atta spp., Camponotus spp., Diprion spp., Dolichovespula spp., Formica spp., Monomorium spp., Neodiprion spp., Paratrechina spp., Pheidole spp., Pogonomyrmex spp., Polistes spp., Solenopsis spp., Technomyrmex, spp., Tetramorium spp., Vespula spp., Vespa spp., and Xilocopa spp. A non-exhaustive list of particular species includes, but is not limited to, Athalia rosae, Atta texana, Caliroa cerasi, Cimbex americana, Iridomyrmex humilis, Linepithema humile, IF-2019-63795218-APN-ANP#INPI Page 27 of 82 Mellifera Scutellata, Monomorium minimum, Monomorium pharaonis, Neodiprion sertifer, Solenopsis invicta, Solenopsis geminata, Solenopsis molesta, Solenopsis fichtery, Solenopsis xiloni, Tapinoma sessile, and Wasmannia auropunctata. (10) Order Isoptera. A non-exhaustive list of particular genera includes, but is not limited to, Coptotermes spp., Cornitermes spp., Cryptotermes spp., Heterotermes spp., Kalotermes spp., Incisitermes spp., Macrotermes spp., Marginitermes spp., Microcerotermes spp., Procornitermes spp., Reticulitermes spp., Schedorhinotermes spp., and Zootermopsis spp. A non-exhaustive list of particular species includes, but is not limited to, Coptotermes acinaciformis, Coptotermes curvignathus, Coptotermes frenchi, Coptotermes formosanus, Coptotermes gestroi, Cryptotermes brevis, Heterotermes aureus, Heterotermes tenuis, Incisitermes minor, Incisitermes snyderí, Microtermes obesi, Nasutitermes corniger, Odontotermes formosanus, Odontotermes obesus, Reticulitermes banyulensis, Reticulitermes grassei, Reticulitermes flavipes, Reticulitermes hageni, Reticulitermes hesperus, Reticulitermes santonensis, Reticulitermes speratus, Reticulitermes tibialis, and Reticulitermes virginicus. (11) Order Lepidoptera. A non-exhaustive list of particular genera includes, but is not limited to, Adoxophyes spp., Agrotis spp., Argyrotaenia spp., Cacoecia spp., Caloptilia spp., Chilo spp., Chrysodeixis spp., Colias spp., Crambus spp., Diaphania spp., Diatraea spp., Earias spp., Ephestia spp., Epimecis spp., Feltia spp., Gortyna spp., Helicoverpa spp., Heliothis spp., Indarbela spp., Lithocolletis spp., Lox agrotis spp., Malacosoma spp., Nemapogon spp., Peridroma spp., Phillonorycter spp., Pseudaletia spp., Plutella spp., Sesamia spp., Spodoptera spp., Synanthedon spp., and Yponomeuta spp.Una lista no exhaustiva de especies particulares incluye, pero no se limita a, Achaea janata, Adoxophyes orana, Agrotis Ípsilon, Alabama argillacea, Amorbia cuneana, Amyelois transitella, Anacamptodes detectaría, Anarsia lineatella, Anomis sabulifera, Anticarsia gemmatalis, Archips argyrospila, Archips rosana, Argyrotaenia citrana, Autographa gamma, Bonagota cranaodes, Borbo cinnara, Bucculatríx thurberiella, Capua. IF-2019-63795218-APN-ANP#INPI Page 28 of 82 reticulana, Carposina niponensis, Chlumetia transversa, Choristoneura rosaceana, Cnaphalocrocis medinalis, Conopomorpha cramerella, Coreyra cephalonica, Cossus cossus, Cydia caryana, Cydia funebrana, Cydia molesta, Cydia nigricana, Cydia pomonella, Darna diducta, Diaphania nitidalis, Diatraea saccharalis, Diatraea grandiosella, Earias insulana, Earias vittalla, Ecdytolopha aurantianum, Elasmopalpus lignosellus, Ephestia cautella, Ephestia elutella, Ephestia kuehniella, Epinotia aporema, Epiphyas postvittana, Erionota thrax, Estigmene aerea, Eupoecilia ambiguella, Euxoa auxiliaris, Galleria mellonella, Grapholita molesta, Hedylepta indicata, Helicoverpa armígera, Helicoverpa zea, Heliothis virescens, Hellula undalis, Keiferia lycopersicella, Leucinodes orbonalis, Leucoptera coffeella, Leucoptera malifoliella, Lobesia botrana, Loxagrotis albicosta, Lymantria dispar, Lyonetia clerkella, Mahasena corbetti, Mamestra brassicae, Manduca sexta, Maruca testulalis, Metisa plana, Mythimna unipuncta, Neoleucinodes elegantalis, Nymphula depunctalis, Operophtera brumata, Ostrinia nubilalis, Oxydia vesulia, Pandemis cerasana, Pandemis heparana, Papilio demodocus, Pectinophora gossypiella, Peridroma saucia, Perileucoptera coffeella, Phthorimaea operculella, Phyllocnistis citrella, Phyllonorycter blancardella, Pieris rapae, Plathypena scabra, Platynota idaeusalis, Plodia interpunctella, Plutella xylostella, Polychrosis viteana, Prays endocarpa, Prays oleae, Pseudaletia unipuncta, Pseudoplusia includens, Rachiplusia nu, Scirpophaga incertulas, Sesamia inferens, Sesamia nonagrioides, Setora nitens, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera exigua, Spodoptera frugiperda, Spodoptera eridania, Theda basilides, Tinea pellionella, Tineola bisselliella, Trichoplusia ni, Tuta absoluta, Zeuzera coffeae, and Zeuzea pyrina. (12) Order Mallophaga. A non-exhaustive list of particular genera includes, but is not limited to, Anaticola spp., Bovicola spp., Chelopistes spp., Goniodes spp., Menacanthus spp., and Trichodectes spp. A non-exhaustive list of particular species includes, but is not limited to, Bovicola bovis, Bovicola caprae, Bovicola ovis, IF-2019-63795218-APN-ANP#INPI Page 29 of 82 Chelopistes meleagridis, Goniodes dissimilis, Goniodes gigas, Menacanthus straminaus, Menopon gallinae, and Trichodectes canis. (13) Order Orthoptera. A non-exhaustive list of particular genera includes, but is not limited to, Melanoplus spp. and Pterophilla spp. A non-exhaustive list of particular species includes, but is not limited to, Acheta domesticas, Anabrus simplex, Grillotalpa africana, Grillotalpa australis, Grillotalpa brachyptera, Grillotalpa hexadactila, Locusta migratoria, Microcentrum retinerve, Schistocerca gregaria, and Scudderia furcata. (14) Order Psocoptera A non-exhaustive list of particular species includes, but is not limited to, Liposcelis decolor, Liposcelis entomophila, Lachesilla quercus, and Trogium pulsatorium. (15) Order Siphonaptera. A non-exhaustive list of particular species includes, but is not limited to, Ceratophillus gallinae, Ceratophillus niger, Ctenocephalides canis, Ctenocephalides felis, and Pulex irritans. (16) Order Thysanoptera. A non-exhaustive list of particular genera includes, but is not limited to, Caliothrips spp., Frankliniella spp., Scirtothrips spp. and Thrips spp. A non-exhaustive list of particular species includes, but is not limited to, Caliothrips phaseoli, Frankliniella bispinosa, Frankliniella fusca, Frankliniella occidentalis, Frankliniella schultzei, Frankliniella tritici, Frankliniella williamsi, Heliothrips haemorrhoidalis, Rhipiphorothrips cruentatus, Scirtothrips citri, Scirtothrips dorsalis, Taeniothrips rhopalantennalis, Thrips hawaiiensis, Thrips nigropilosus, Thrips orientalis, Thrips palmi, and Thrips tabaci. (17) Order Thysanura. A non-exhaustive list of particular genera includes, but is not limited to, Lepisma spp. and Thermobia spp. (18) Order Acarina. A non-exhaustive list of particular genera includes, but is not limited to, Acaras spp., Aculops spp., Argus spp., Boophilus spp., Demodex spp., Dermacentor spp., Epitrimerus spp., Eriophyes spp., Ixodes spp., Oligonychus spp., Panonychus spp., Rhizoglyphus spp., and Tetranychus spp. IF-2019-63795218-APN-ANP#INPI Page 30 of 82 particular species include, but are not limited to, Acarapis woodi, Acarus siró, Acena mangiferae, Aculops lycopersici, Aculus pelekassi, Aculus schlechtendah, Amblyomma americanum, Brevipalpus obovatus, Brevipalpus phoenicís, Dermacentor variabilis, Dermatophagoides pteronyssinus, Eotetranychus carpini, Liponyssoides sanguineus, Notoedres cati, Oligonychus coffeae, Oligonychus ilicis, Ornithonyssus bacoti, Panonychus citri, Panonychus ulmi, Phillocoptruta oleivora, Polyphagotarsonemus latus, Rhipicephalus sanguineus, Sarcoptes scabiei, Tegolophus perseaflorae, Tetranychus urticae, Tyrophagus longior and Varroa destructor. (19) Order of Spiders. A non-exhaustive list of particular genera includes, but is not limited to, Loxosceles spp., Latrodectus spp. y Atrax spp. A non-exhaustive list of particular species includes, but is not limited to, Loxosceles reclusa, Latrodectus mactans and Atrax robustus. (20) Class Symfila. A non-exhaustive list of particular species includes, but is not limited to, Scutigerella immaculata. (21) Subclass Collembola. A non-exhaustive list of particular species includes, but is not limited to, Bourletiella hortensis, Onychiurus armatus, Onychiurus fimetarius and Sminthurus viridis. (22) Phylum Nematoda. A non-exhaustive list of particular genera includes, but is not limited to, Aphelenchoides spp., Belonolaimus spp., Criconemella spp., Ditilénchus spp., Globodera spp., Heterodera spp., Hirschmanniella spp., Hoplolaimus spp., Meloidogyne spp., Pratilenchus spp. and Radofolus spp. A non-exhaustive list of particular species includes, but is not limited to, Dirofilaria immitis, Globodera pallida, Heterodera glycines, Heterodera zeae, Meloidogyne incognita, Meloidogyne javanica, Onchocerca volvulus, Pratilenchus penetrans, Radofolus similis and Rotilenchulus reniform is. IF-2019-63795218-APN-ANP#iNPI Page 31 of 82 (23) Phylum Mollusca. A non-exhaustive list of particular species includes, but is not limited to, Arion vulgaris, Cornu aspersum, Deroceras reticulatum, Umax flavus, Milax gagates and Pomacea canaliculata. Sap-feeding pests are a particularly favored group for control. Sap-feeding pests generally have piercing and / or sucking mouthparts and feed on the sap and internal plant tissues. Examples of sap-feeding pests of particular agricultural concern include, but are not limited to, aphids, cicadas, scale insects, spider mites, psyllids, fulgoromorphs, mealybugs, stink bugs, and whiteflies. Specific examples of orders that have sap-feeding pests of agricultural concern include, but are not limited to, Anoplura and Hemiptera. Specific examples of Hemiptera that are of concern to agriculture include, but are not limited to, Aulacaspis spp., Aphrophora spp., Aphis spp., Bemisia spp., Coccus spp., Euschistus spp., Lygus spp., Macrosiphum spp., Nezara spp., Rhopalosiphum spp., Sogatella spp., Nilaparvata spp., Laodelphax spp., and Nephotettix spp. Another group of pests particularly favored for control are chewing pests. Chewing pests, in general, have mouthparts that allow them to chew plant tissue, including roots, stems, leaves, shoots, and reproductive tissues (which include, but are not limited to, flowers, fruits, and seeds). Examples of chewing pests of particular agricultural concern include, but are not limited to, caterpillars, beetles, grasshoppers, and locusts. Specific examples of orders that have chewing pests of agricultural concern include, but are not limited to, Coleoptera, Lepidoptera, and Orthoptera. Specific examples of Coleoptera that are of agricultural concern include, but are not limited to, Anthonomus spp., Cerotoma spp., Chaetocnema spp., Colaspis spp., and Cyclocephala spp. IF-2019-63795218-APN-ANP#INPI Page 32 of 82 Diabrotica spp., Hypera spp., Phiilophaga spp., Phillotreta spp., Sphenophorus spp., Sitophilus spp. The phrase “pesticide effective quantity” refers to the amount of pesticide needed to achieve an observable effect on a pest, such as necrosis, death, retardation, prevention, elimination, destruction, or any other reduction in the occurrence and / or activity of a pest at a given location. This effect can occur when pest populations are repelled from a location, pests are incapacitated at or around a location, and / or pests are exterminated at or around a location. Of course, a combination of these effects can occur. Generally, pest populations, their activity, or both are conveniently reduced by more than 50 percent, preferably more than 90 percent, and most preferably more than 99 percent.In general, an effective pesticide application rate for agricultural purposes is approximately 0.0001 grams per hectare to approximately 5000 grams per hectare, preferably approximately 0.0001 grams per hectare to approximately 500 grams per hectare, and even more preferably approximately 0.0001 grams per hectare to approximately 50 grams per hectare. Alternatively, approximately 150 grams per hectare to approximately 250 grams per hectare may be used against pests. Detailed description of the invention This document describes the molecule A / -(3-chloro-1 -(pyridin-3-yl)-1 H-pyrazol-4-yl)-2(methylsulfonyl)propanamide: IF-2019-63795218-APN-ANP#iNPi Page 33 of 82 Formula One also known as F1 Formula One may exist in different geometric or optical isomeric or tautomeric forms. One or more chiral centers may be present, in which case Formula One may exist as pure enantiomers, mixtures of enantiomers, pure diastereomers, or mixtures of diastereomers. Those skilled in the art will appreciate that one stereoisomer may be more active than the other stereoisomers. Individual stereoisomers may be obtained by known selective synthesis procedures, by conventional synthesis procedures using resolved starting materials, or by conventional resolution procedures. Tautomerization centers may be present. This description covers all such isomers, tautomers, and mixtures thereof, in all proportions.The structures described in this description are described in a single geometric form for clarity, but are intended to represent all 15 geometric forms of the molecule. Formula One (F1) Summary Starting materials, reagents, and solvents obtained from commercial sources were used without further purification. Anhydrous solvents were purchased as Aldrich Sure / Seal™ and used as received. Melting points were obtained using a Thomas Hoover Unimelt Capillary Melting Point Instrument or a Stanford Research Systems OptiMelt Automated Melting Point System and are uncorrected. Examples using “room temperature” were performed in climate-controlled laboratories with temperatures at room temperature. IF-2019-63795218-APN-ANP#INPI Page 34 of 82. The temperature range is approximately 20 °C to approximately 24 °C. Molecules are given their known names, in accordance with the nomenclature programs within ISIS Draw, ChemDraw, or ACD Name Pro. If such programs are unable to name a molecule, the molecule is named using the rules of conventional nomenclature. Spectral data for 1H NMR are in ppm (δ) and were recorded at 300, 400, 500, or 600 MHz; spectral data for 13C NMR are in ppm (δ) and were recorded at 75, 100, or 150 MHz; and spectral data for 19F NMR are in ppm (δ) and were recorded at 376 MHz, unless otherwise stated. An expert in the field will also recognize that the synthesis of 10 desired molecules can be achieved by carrying out some of the steps of the synthetic routes in a different order than described. An expert in the field will further recognize that standard functional group interconversions or substitution reactions can be performed on the desired molecules to introduce or modify substituents. Example 1: Preparation of 3-chloro-1(pyridin-3-yl)-1H-pyrazol-4-amine (C5) Cl C5 Step 1 — Preparation of 3-chloro-1H-pyrazol-4-amino hydrochloride (C2): A 2-liter (L) three-necked round-bottom flask with a top stirrer and a probe was fitted IF-2019-63795218-APN-ANP#INPI Page 35 of 82 A three-necked flask was prepared with a temperature control, an addition funnel, and a nitrogen inlet. Ethanol (600 mL) and 4-nitro-1 / - / -pyrazole (C11, 50.6 g, 447 mmol) were added to this flask. Concentrated hydrochloric acid (HCl, 368 mL) was added to this solution in one portion (note: rapid exothermic process from 15 °C to 39 °C), and the resulting mixture was purged with nitrogen (N2) for 5 minutes. Palladium in alumina (5% w / w) (2.6 g) was added, and the mixture was stirred at room temperature while triethylsilane (208 g, 1789 mmol) was added dropwise for 4 hours. The reaction mixture, which was slowly heated from 35 to 55 °C for 2 h, was stirred for a total of 16 h. The mixture was vacuum filtered through a Celite® stopper and a two-phase mixture was collected.The two-phase mixture was transferred to a separatory funnel, and the lower aqueous layer was collected and evaporated to dryness using rotary evaporation (60 °C, 50 mmHg) with the aid of acetonitrile (3 x 350 mL). The resulting yellow solid was suspended in acetonitrile (150 mL) and allowed to stand for 2 hours at room temperature followed by 1 hour at 0 °C in a refrigerator. The solids were filtered and washed with acetonitrile (100 mL) to provide the base compound as a white solid (84 g, 97% yield, 80% purity): mp 190-193 °C;1H NMR (400 MHz, DMSO-d6) δ 10.46 - 10.24 (br s, 2H), 8.03 (s, 0.54H), 7.75 (s, 0.46H), 5.95 (brs, 1H);13C-NMR (101 Mhz, DMSO-d6) δ 128.24, 125.97, 116.71. Step 2 - Preparation of tere-butyl (3-chloro-1 / 4-pyramol-4-yl)carbamate (C3): In a 2 L round-bottom flask, 3-chloro-1 / - / -pyrazol-4-amino hydrochloride (C2; 100 g, 649 mmol) and tetrahydrofuran (THF; 500 mL) were added. To this mixture, di-tert-butyl dicarbonate (156 g, 714 mmol), sodium bicarbonate (120 g, 1429 mmol), and water (50.0 mL) were sequentially added. The mixture was stirred for 16 h, diluted with water (500 mL) and ethyl acetate (EtoAc; 500 mL), and transferred to a separatory funnel. This yielded three layers: a) bottom layer - white gelatinous precipitate; b) middle layer - light yellow aqueous liquid; yc) upper layer - coppery organic liquid. The phases were separated, collecting the lower and middle layers (i.e., aqueous phase) in a way IF-2019-63795218-APN-ANP#INPI Page 36 of 82 The aqueous phase was extracted with EtOAc (2 x 200 mL) and the organic extracts were combined, washed with brine (200 mL), dried over anhydrous sodium sulfate, filtered, and concentrated by rotary evaporation to yield a thick, coppery-colored oil (160 g). The thick oil was suspended in hexane (1000 mL) and stirred at 55 °C for 2 h. This resulted in a light brown suspension. The mixture was cooled to 0 °C, and the solid was collected by vacuum filtration and rinsed with hexane (2 x 10 mL). The sample was air-dried to constant mass to provide the base compound as a light brown solid (103 g, 72% yield, 80% purity): mp 137-138 °C;1H NMR (400 MHz, CDCI3) δ 10.69 (s, 1H), 7.91 (s, 1H), 1.52 (s, 9H). Step 3 - Preparation of tere-butyl (3-chloro-1-(pyridin-3-yl)-1 / - / -pyrazol-4-yl)carbamate (C4): A dry 2 L three-necked round-bottom flask was fitted with a mechanical stirrer, nitrogen inlet, thermometer, and reflux condenser. 3-iodopyridine (113 g, 551 mmol), tere-butyl (3-chloro-1 / - / -pyrazol-4-yl)carbamate (C3; 100 g, 459 mmol), potassium phosphate powder (195 g, 919 mmol), and copper chloride (3.09 g, 23 mmol) were added to this flask. Acetonitrile (1 L) and A / 1,A / 2-dimethylethane-1,2-diamine (101 g, 1149 mmol) were added sequentially, and the mixture was heated to 81 °C for 4 h. The mixture was cooled to room temperature and filtered through a Celite® bed. The filtrate was transferred to a 4 L Erlenmeyer flask fitted with a mechanical stirrer and diluted with water to a total volume of approximately 4 L. The mixture was stirred for 30 min at room temperature, and the resulting solid was collected by vacuum filtration.The solid was washed with water and oven-dried for several days under vacuum at 40 °C to constant weight to provide the base compound as a pale brown solid (117.8 g, 87% yield, 80% purity): mp 140143 °C;1H NMR (400 MHz, CDCI3) δ 8.96 (s, 1H), 8.53 (dd, J = 4.7, 1.2 Hz, 1H), 8.36 (s, 1H), 7.98 (ddd, J = 8.3, 2.7, 1.4 Hz, 1H), 7.38 (dd, J = 8.3, 4.8 Hz, 1H), 6.37 (s, 1H), 1.54 (s, 9H)¡ ESIMS m / z 338 ([Mt-Bu]+), 220 ([MO-í-Bu]'). IF-2019-63795218-APN-ANP#iNPi Page 37 of 82 Step 4 - Preparation of 3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-amine (O5): Trifluoroacetic acid (AFC; 6.79 mL) was added to tert-butyl (3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)carbamate (C4; 2 g, 6.79 mmol) in dichloromethane (DCM; 6.79 mL) and the mixture was stirred at room temperature for 2 h. Toluene (12 mL) was added and the reaction mixture was concentrated under vacuum to near dryness. The concentrated reaction mixture was poured into a separatory funnel containing saturated aqueous sodium bicarbonate and extracted with DCM (3 x 10 mL). The combined organic layers were concentrated to provide the title compound as a white solid (0.954 g, 72%): mp 137.9—139.9 °C;1H NMR (400 MHz, CDCI3) δ 8.84 (d, J = 2.4 Hz, 1H), 8.50 (dd, J = 4.7, 1.4 Hz, 1H), 7.95 (ddd, J = 8.3, 2.7, 1.5 Hz, 1H), 7.52 (s, 1H), 7.37 (ddd, J = 8.4, 4.7, 0.7 Hz, 1H), 3.18 (s, 2H); ESIMS m / z 196 ([M+H])*). Example 2; Preparation of / V-(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-2-(methylsulfonyl)propanamide (Formula One) C7 NaBO4 AcOH Formula One Fund Step 1- Preparation of A / -(3-chloro-1-(pyridin-3-yl)-1Hpyrazol-4-yl)-2-(methylthio)propanamide (C7): To a suspension of 3-chloro-1-(pyridin-3-yl)-1 / 7-pyrazol-4-amine (C5; 0.1 g, 0.514 mmol) and 2-(methylthio)propanoic acid (C6; 0.185 g, 1.541 mmol) in DCM (1.713 mL) were sequentially added / V,A / -dimethylpyridin-4-amine (0.220 g, 1.798 mmol) and A / 1-((ethylimino)methylene)-A / 3, / V3-dimethylpropan-1,3-diamine hydrochloride (0.305 IF-2019-63795218-APN-ANP#INPI Page 38 of 82 g, 1,593 mmol). The reaction mixture was stirred at room temperature for 18 hours and concentrated. Purification by silica gel chromatography (EtOAc / hexanes 0-100%) gave the base compound as a white solid (116 mg, 72%): mp 129-132 °C;1H NMR (400 MHz, CDCI3) δ 8.98 (d, J = 2.4 Hz, 1H), 8.63 (s, 1H), 8.58 - 8.53 (m, 1H), 8.03-7.96 (m, 1H), 7.43-7.37 (m, 1H), 3.59-3.48 (m, 1H), 2.18 (s, 3H), 1.59 (d J = 7.3 Hz, 3H), ESIMS m / z 297 ([M+1 ]+). Step 2 - Preparation of A / -(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-2-(methylsulfonyl)propanamide (Formula One): A / -(3-chloro-1-(pyridin-3-yl)-1 / - / -pyrazol-4-yl)-2-(methylthio)propanamide (C7; 882 mg, 2.97 mmol), acetic acid (6.0 mL), and sodium perborate tetrahydrate (915 mg, 5.94 mmol) were added to a 100 mL round-bottom flask. The reaction mixture was stirred overnight under an inert atmosphere in a heating block heated to 50 °C. The reaction mixture was then poured into a brine solution and extracted with DCM (3 x 20 mL). The combined organic extracts were dried over magnesium sulfate, filtered, and concentrated.Purification of the resulting residue by silica gel chromatography (0.10% methanol in DCM) yielded the base compound as a white foam (734 mg, 74%):1H NMR (400 MHz, DMSO-d6) δ 10.41 (s, 1H), 9.07 (d, J = 2.7 Hz, 1H), 8.94 (s, 1H), 8.55 (dd, J = 4.7, 1.4 Hz, 1H), 8.23 ​​(ddd, J = 8.4, 2.8, 1.4 Hz, 1H), 7.55 (ddd, J = 8.4, 4.8, 0.7 Hz, 1H), 4.41 (q, J = 7.0 Hz, 1H), 3.07 (s, 3H), 1.57 (d, J = 7.1 Hz, 3H); ESIMS m / z 329 ([M+H]+); IR (thin film) 1680 cm'1. IF-2019-63795218-APN-ANP#INPI Page 39 of 82 Synthesis of comparative molecules Example 3: Preparation of 3-chloro- / V-methyl-1-(pyridin-3-yl)-1H-pyrazol-4-amine (09) Step 1 - Preparation of tere-butyl (3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)(methyl)carbamate (C8): To a solution of tere-butyl 3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-ylcarbamate (C4; 1.0 g, 3.39 mmol) in 1V-dimethylformamide (16.96 mL) at 0 °C, sodium hydride (0.163 g, 4.07 mmol) was added. After 30 min, the flask was warmed to room temperature and the reaction mixture was stirred for another 30 min. Iodomethane (0.232 mL, 3.73 mmol) was added to the flask, and the reaction mixture was stirred at room temperature for 2 h. The reaction was stopped by adding saturated ammonium chloride. The reaction mixture was extracted twice with tert-butyl methyl ether. The organic layer was dried over sodium sulfate, filtered, and concentrated. Purification by silica gel column chromatography (EtOAc / hexanes 0–100%) yielded the parent compound as a yellow oil (983 mg, 94%).1H NMR (400 MHz, CDCI3) δ 8.91 (d, J= 2.5 Hz, 1H), 8.64 - 8.48 (m, 1H), 8.01 (d, J = 7.5 Hz, 1H), 7.90 (s, 1H), 7.41 (dd, J = 8.3, 4.8 Hz, 1H), 3.23 (s, 3H), 1.58 - 1.25 (m, 9H); ESIMS m / z 309 ([M+H]+); IR (thin film) 1693 cm'1. Step 2 - Preparation of 3-chloro-N-methyl-1-(pyridin-3-II)-1H-pyrazol-4-amine (C9): Trifluoroacetic acid (AFC; 5.4 mL) was added to tere-butyl (3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)(methyl)carbamate (C8; 1.65 g, 5.34 mmol) in DCM (5.4 mL) and the mixture was IF-2019-63795218-APN-ANP#INPI Page 40 of 82 The mixture was stirred at room temperature for 1 h. Toluene was added, and the reaction mixture was concentrated under vacuum to near dryness. The concentrated reaction mixture was poured into a separatory funnel containing saturated sodium bicarbonate, and the mixture was extracted with EtOAc (3 x 20 mL). The extracts were combined, dried over magnesium sulfate, filtered, and concentrated to dryness. The base compound was isolated as a pale yellow solid (0.92 g, 83%): mp 108-118 °C;1H NMR (400 MHz, CDCI3) δ 8.88 (d, J = 2.4 Hz, 1H), 8.48 (dd, J = 4.7, 1.4 Hz, 1H), 7.96 (ddd, J = 8.3, 2.7, 1.4 Hz, 1H), 7.41 - 7.29 (m, 2H), 2.87 (s, 3H); EIMS m / z 208. Example 4: Preparation of / V-(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-N-methyl-2-(methylsulfonyl)propanamide (comparative example 1 also known as CE1) either CH3C6b NaBO4 AcOH Com| Comparative Example 1 Step 1 - Preparation of A / -(3-chloro-1-(pyridin-3-yl)-1 / - / pyrazol-4-yl)-A / -methyl-2-(methylthio)propanamide (C10): Oxalyl dichloride (0.384 mL, 4.40 mmol) and one drop of dimethylformamide were added to a solution of 2-(methylthio)propanoic acid (C6; 481 mg, 4.00 mmol) in DCM (6 mL). Vigorous bubbling was observed, and stirring was continued for 30 minutes. The crude acyl chloride reaction mixture (C6b) was concentrated under vacuum to near dryness. The concentrated reaction mixture (C6b) was dissolved in DCM (3 mL) and added slowly (over ~5 min) to an ice-cold solution IF-2019-63795218-APN-ANP#INPI Page 41 of 82 of 3-chloro- / V-methyl-1-(pyridin-3-yl)-1H-pyrazol-4-amine (C9; 417 mg, 2 mmol) and A / -ethyl-A / isopropylpropan-2-amine (0.751 mL, 4.40 mmol) in DCM (3 mL). The resulting dark orange solution was heated slowly to room temperature for 0.5 hours and stirred at room temperature for 1.5 hours. The reaction mixture was quenched by adding a saturated sodium bicarbonate solution. The reaction mixture was extracted with DCM (3 x 10 mL). Purification of the residue by silica gel chromatography (EtOAc / hexane 0-100%) gave the parent compound as a white solid (495 mg, 76%). mp 128-133 °C;1H NMR (400 MHz, CDCI3) δ 8.94 (d, J = 2.4 Hz, 1H), 8.62 (d, J = 3.8 Hz, 1H), 8.15 (s, 1H), 8.03 (d, J = 8.3 Hz, 1H), 7.46 (dd, J= 8.3, 4.8 Hz, 1H), 3.34 (q J = 6.8 Hz, 1H), 3.26 (s, 3H), 2.10 (s, 3H), 1.45 (d J = 6.9 Hz, 3H); ESIMS m / z 311 ([M+1 ]+). Step 2 - Preparation of A / -(3-chloro-1-(pyridin-3-yl)-1-pyrazol-4-yl)- / V-methyl-2-(methylsulfonyl)propanamide (comparative example 1): To a 20 mL vial, / V-(3-chloro-1-(pyridin-3-yl)-1 / - / -pyrazol-4-yl)-A / -methyl-2-(methylthio)propanamide (C10; 306 mg, 0.985 mmol), acetic acid (2 mL), and sodium perborate tetrahydrate (333 mg, 2.17 mmol) were sequentially added. The solution was heated to 65 °C for 3 h, cooled, and quenched by the slow addition of a saturated sodium bicarbonate solution. The solution was extracted with DCM (3 x 10 mL) and the combined organic extracts were dried and concentrated.Purification of the resulting mixture by silica gel chromatography (0-10% methanol in DCM) yielded the base compound as a whitish solid (221 mg, 62%):1H NMR (400 MHz, CDCI3) δ 8.97 (dd, J = 2.7, 0.7 Hz, 1H), 8.64 (dd, J = 4.7, 1.5 Hz, 1H), 8.22 (s, 1H), 8.00 (ddd, J = 8.4, 2.7, 1.5 Hz, 1H), 7.45 (ddd, J = 8.4, 4.8, 0.8 Hz, 1H), 4.14 - 3.94 (m, 1H), 3.33 (s, 3H), 3.02 (d, J = 0.8 Hz, 3H), 1.65 (d, J = 7.0 Hz, 3H); ESIMS m / z 343 ([M+1 ]+); IR (thin film) 1657 cm'1. IF-2019-63795218-APN-ANP#INPI Page 42 of 82 Example 5: Preparation of N-(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)- / V-methyl-2-(methylsulfonyl)acetamide (comparative example 2 also known as CE2): C12 NaBO4 AcOH Comparative Example 2 Step 1- Preparation of A / -(3-chloro-1-(pyridin-3-yl)-1-pyrazol-4-yl)- / V-methyl-2(methylthio)acetamide (C12): To a 20 mL vial, 3-chloro-A / methyl-1-(pyridin-3-yl)-1 / 7-pyrazol-4-amine (C9; 417 mg, 2 mmol), 2-(methylthio)acetic acid (C11; 318 mg, 3 mmol), A / 1-((ethylimino)methylene)-A / 3,A / 3-dimethylpropane-1,3-diamine hydrochloride (767 mg, 4 mmol), A / ,A / -dimethylpyridine-4-amine (611 mg, 5 mmol), and dichloroethane (6 mL) were sequentially added. The mixture was stirred at room temperature for 18 hours and concentrated. Purification by silica gel chromatography (EtOAc / hexanes 0-100%) yielded the base compound as a pale yellow oil (517 g, 83%):1H NMR (400 Mhz, CDCI3) δ 8.95 (d, J = 2.5 Hz, 1H), 8.62 (dd, J = 4.8, 1.4 Hz, 1H), 8.13 (s, 1H), 8.04 (ddd, J = 8.3, 2.7, 1.4 Hz, 1H), 7.50 - 7.43 (m, 1H), 3.26 (s, 3H), 3.12 (s, 2H), 2.24 (s, 3H);13C NMR (101 Mhz, CDCI3) δ 170.00, 148.61, 140.15, 140.03, 135.68, 126.56, 126.42, 125.33, 124.15, 37.16, 34.94, 16.22; ESIMS m / z 297 ([M+H]+). Step 2 - Preparation of A / -(3-chloro-1-(pyridin-3-yl)-1 / - / pyrazol-4-yl)-A / -methyl-2-(methylsulfonyl)acetamide (comparative example 2): A / -(3-chloro-1-(pyridin-3-yl)-1 / - / pyrazol-4-yl)- / V-methyl-2-(methylthio)acetamide (C12; 262 mg, 0.883 mmol), acetic acid (1.5 mL) and sodium perborate tetrahydrate were sequentially added to a 7 mL vial IF-2019-63795218-APN-ANP#iNPi Page 43 of 82 (299 mg, 1,942 mmol). The mixture was stirred at 65 °C for 2 h, then quenched by the addition of a saturated sodium bicarbonate solution. The reaction mixture was extracted with DCM (3 x 10 mL). The combined organic extracts were dried and concentrated. Purification of the resulting mixture by silica gel chromatography (0-10% methanol in DCM) yielded the base compound as a white semi-solid (192 mg, 62.8%):1H NMR (500 MHz, CDCI3) δ 8.97 (d, J = 2.6 Hz, 1H), 8.64 (dd, J = 4.9, 1.3 Hz, 1H), 8.24 (s, 1H), 8.00 (ddd, J = 8.4, 2.8, 1.4 Hz, 1H), 7.45 (dd, J = 8.4, 4.8 Hz, 1H), 3.96 (s, 2H), 3.33 (s, 3H), 3.20 (s, 3H); ESIMS m / z 329 ((M+H]+); IR (thin film) 1664 cm'1. Example 6: Preparation of / V-(3-chloro-1-(pyridin-3-1l)-1H-pyrazol-4-1l)-2-(methylsulfonyl)acetamide (Formula Two also known as CE3) or Formula Two C15 Step 1- Preparation of / V-(3-chloro-1-(pyridin-3-¡l)-1 / - / pyrazol-4-yl)-215 (methylthio)acetamide (C14): To a suspension of 3-chloro-1-(pyridin-3-¡l)-1 / - / -pyrazol-4-amine (C5; 1.0 g, 5.14 mmol), To / ,A / -dimethylpyridin-4-amine (628 mg, 5.14 mmol), and 2(methylthio)acetic acid (C13; 654 mg, 6.17 mmol) in dichloroethane (6 mL) were added N1((ethylimino)methylene)-A / 3,A / 3-dimethylpropan-1,3-diamine hydrochloride (1.477 mg, 7.71 mmol). The reaction mixture was stirred at room temperature for 24 hours. The mixture was diluted with DCM and washed with saturated aqueous ammonium chloride and brine, then dried on IF-2019-63795218-APN-ANP#iNPi Page 44 of 82 magnesium sulfate and was concentrated under vacuum to give a brown gum. Purification of the gum by silica gel chromatography (DCM-methanol) provided the base compound as a white solid (1.268 g, 87%):1H NMR (400 MHz, CDCI3) δ 9.06 - 8.90 (m, 1H), 8.74 (s, 1H), 8.64 (s, 1H), 8.57 - 8.45 (m, 1H), 8.05 - 7.90 (m, 1H), 7.46 - 7.33 (m, 1H), 3.41 (s, 2H), 2.24 (s, 3H); ESIMS m / z 283 ([M+Hf). Step 2 - Preparation of A / -(3-chloro-1-(pyridin-3-yl)-1Hpyrazol-4-yl)-2-(methylsulfonyl)acetamide (Formula Two): To a solution of A / -(3-chloro-1-(pyridin-3-yl)-1Hpyrazol-4-yl)-2-(methylthio)acetamide (C14; 160 mg, 0.566 mmol) in acetic acid (1.5 mL) sodium perborate tetrahydrate (183 mg, 1.188 mmol) was added. The reaction mixture was stirred at 60 °C for 2 h. The reaction mixture was cooled and then poured into an excess of saturated sodium bicarbonate solution and extracted with DCM. Purification of the resulting residue by silica gel chromatography (0-10% methanol in DCM) gave the base compound as a white solid (101 mg, 53.9%) and / V-(3-chloro-1(pyridin-3-yl)-1 / - / -pyrazol-4-yl)-2-(methylsulfinyl)acetamide (C15) as a white solid (40 mg, 22.5%). A / -(3-chloro-1-(pyridin-3-yl)-1Hpyrazol-4-yl)-2-(methylsulfon¡l)acetamide (Formula Two):1H NMR (300 MHz, CDCI3) δ 8.95 (dd, J = 2.7, 0.8 Hz, 18, J = 6.6, J Hz, 1H), 8.53 (dd, J = 4.8, 1.4 Hz, 1H), 8.04 (ddd, J = 8.4, 2.7, 1.4 Hz, 1H), 7.45 (ddd, J = 8.3, 4.8, 0.7 Hz, 1H, 2.4), J = 2, Hz 3.21 (t, J = 0.8 Hz, 3H); ESIMS m / z 315 ([M+H]*); IR 20 (thin film) 1677 cm'1. N-(3-chloro-1-(pyridin-3-yl)-1Hpyrazol-4-yl)-2-(methylsulfinyl)acetamide (C15):1H NMR (300 MHz, CDCI3) δ 8.95 (dd, J = 2.7, 0.8 Hz, 1H, 18, J = 0.7, J 8.53 (dd, J = 4.8, 1.4 Hz, 1H), 8.04 (ddd, J = 8.4, 2.7, 1.5 Hz, 1H), 7.45 (ddd, J = 8.4, 4.8, 0.8 Hz, 1H), 3.93 (d, 3.1 Hz, 3.1 Hz), (d, J = 13.8 Hz, 1H), 2.80 (s, 3H); ESIMS m / z 299 25 ([M+H]+)¡ IR (thin film) 1673 cm'1. IF-2019-63795218-APN-ANP#INPI Page 45 of 82 Example 7: Preparation of / V-(3-chloro-1-(pyridine-3-yl)-1H-pyrazol-4-yl)-2-(methylsulfonyl)acetamide (Formula Three also known as CE4) or h3c ch3 C16 1. l¡oh»h2o THF, MeOH, H2O 2. SOCI2, PhCH3, reflux Formula Three Step 1 - Preparation of 2-methyl-2-(methylthio)propanoyl (C17) chloride: A 100 mL round-bottom flask was loaded with ethyl 2-methyl-2-(methylthio)propanoate (C16; 500 mg, 3.08 mmol), lithium hydroxide hydrate (400 mg, 9.53 mmol), THF (6.0 mL), methanol (2.0 mL), and water (2.0 mL). The reaction mixture was allowed to stand at room temperature overnight. The reaction mixture was acidified with normal (N) HCl and extracted with EtOAc (3 x 15 mL). The combined organic extracts were dried over magnesium sulfate, filtered, and concentrated. The base compound can be prepared from the above acid as in Liu, Aiping; Ren, Yeguo; Huang, Lu; Pei, Hui; Hu, Zhibin; Lin, Xuemei; Cheng, Sixi; Huang, Mingzhi; Zhu, Xiaoxing; Wei, Tianlong CN 101928271, 2010. It was isolated (without purification) as a colorless solid (394 mg, 83%): 1NMR H (500 MHz, DMSO-ds) δ 2.05 (s, 3H), 1.39 (s, 6H), 1513C NMR (126 Mhz, DMSO-d6) δ 174.01, 45.08, 24.31, 11.73; IR (thin film) 3394, 1652, 1204, 1040, 1024, 995 cm'1. IF-2019-63795218-APN-ANP#INPI Page 46 of 82 Step 2 - Preparation of A / -(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-2-methyl-2(methylthio)propanamide (C18): A 50 mL round-bottom flask was loaded with 2-methyl-2-(methylthio)propanoyl chloride from Step 1 (C17; 200 mg, 1,310 mmol), 3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-amine (C5; 255 mg, 1,310 mmol), and dichloroethane (6,552 mL). NETyl-N-isopropylpropan-2-amine (456 mL, 2.62 mmol) was added under an inert atmosphere. The reaction mixture was allowed to be stirred at room temperature for 3 hours and was concentrated. The reaction was stopped by pouring into a brine solution, and the reaction mixture was extracted with DCM (2 x 15 mL). The combined organic extracts were dried over magnesium sulfate, filtered, and concentrated.Purification of the resulting residue by silica gel chromatography (EtOAc / hexanes 0-80%) yielded the base compound as a light orange residue (191 mg, 46.4%):1H NMR (400 MHz, DMSO-cf6) δ 9.37 (s, 1H), 9.07 (dd, J = 2.8, 0.7 Hz, 1H), 8.78 (s, 1H), 8.55 (dd, J = 4.7, 1.4 Hz, 1H), 8.22 (ddd, J = 8.3, 2.7, 1.4 Hz, 1H), 7.56 (ddd, J = 8.4, 4.8, 0.8 Hz, 1H), 2.10 (s, 3H), 1.53 (s, 6H);13C NMR (126 MHz, DMSO-d6) δ 171.99, 147.05, 138.78, 136.62, 134.86, 125.02, 124.85, 123.72, 119.01, 47.13, 24.99, 11.65; IR (thin film) 1675, 1484, 1388, 1353, 947, 800, 702 cm'1; ESIMS m / z 311 ([M+H]+). Step 3 - Preparation of A / -(3-chloro-1-(pyridin-3-yl)-1 / 7-pyrazol-4-yl)-2-methyl-2-(methylsulfonyl)propanamide (Formula Three): A 25 mL vial was loaded with A / -(3-chloro-1-(pyridin-3-yl)-1 / 7-pyrazol-4-yl)-2-methyl-2-(methylthio)propanamide (C18; 75 mg, 0.241 mmol), sodium perborate tetrahydrate (74 mg, 0.483 mmol), and acetic acid (2.0 mL) was added. The reaction mixture was stirred in a heating block at 50 °C for 3 h. The reaction mixture was diluted with water (7 mL) and extracted with DCM (3 x 7 mL). The combined organic extracts were dried on magnesium sulfate, filtered, and concentrated. Purification of the resulting residue by silica gel chromatography (EtOAc / hexanes 0-75%) yielded the base compound as a white solid (47 mg, 56.2%):1H NMR (400 MHz, DMSO-6) δ 9.50 (s, 1H), 9.07 (d, J = 2.6 Hz, 1H), 8.83 (s, 1H), 8.56 (dd, J = 4.7, 1.4 Hz, 1H), 8.23 ​​(ddd, J = 8.4, 2.8, 1.4 Hz, 1H), 7.68 IF-2019-63795218-APN-ANP#INPI Page 47 of 82 7.49 (m, 1H), 3.10 (s, 3H), 1.66 (s, 6H);13C NMR (101 MHz, DMSO-cfe) δ 167.92, 148.27, 139.99, 137.59, 135.89, 126.34, 126.09, 124.77, 119.33, 67.49, 36.97, 19.76; IR (thin film) 1678, 1292, 1108, 946, 800, 701 cm'1; ESIMS m / z 343 ((M+Hf). Biological assays The following bioassays were conducted against the green peach aphid (Myzus persicae) and the sweet potato whitefly (Bemisia tabaci), which are good indicator species for a wide range of sap-feeding pests. The results with these two indicator species demonstrate the broad utility of Formula One in the control of sap-feeding insects. Testing solutions: F1, CE1, CE2, CE3, and CE4 (2 mg each) were dissolved in 2 mL of acetone / methanol (1:1) solvent, forming 1000 ppm stock solutions for each test molecule. The stock solutions were diluted 5X with 0.025% Tween® 20 in water to obtain 200 ppm test solutions for each test molecule. Subsequent 4X dilutions in water with 0.025% Tween® 20 and 10% acetone / methanol (1:1) were used to generate the desired concentrations for the dose responses. A minimum of 5 concentrations of each test molecule were used for each assay. Bioassay 1: Green peach aphid (Myzus persicae, MYZUPE) (“GPA”). The peach aphid (GPA) is the most significant aphid pest of peach trees, causing stunted growth, leaf shrinkage, and death of various tissues. It is also dangerous because it acts as a vector for the transmission of plant viruses, such as potato virus Y and potato leaf virus to members of the nightshade / potato Solanaceae family, and various mosaic viruses to many other food crops. The GPA attacks plants such as broccoli, burdock, cabbage, and carrots. IF-2019-63795218-APN-ANP#INPI Page 48 of 82 Cauliflower, radish, eggplant, green beans, lettuce, macadamia nuts, papaya, peppers, sweet potatoes, tomatoes, watercress, and zucchini are among the crops that GPA attacks. It also infests many ornamental plants such as carnations, chrysanthemums, white flowering flowers, poinsettias, and roses. GPA has developed resistance to many pesticides. Currently, it has the third highest number of reported cases of insect resistance (Sparks and others). Consequently, based on the factors mentioned above, controlling this pest is important. Furthermore, the molecules that control this pest (GPA), which is known as a sap-feeding pest, are also useful for controlling other sap-feeding pests. Formula One test solutions and comparative examples, prepared as described above, were analyzed against GPA using the following procedure. Cabbage seedlings grown in 3-inch pots, with 2–3 small true leaves (3–5 cm), were used as the test substrate. The seedlings were infested with 20–50 GPA (at nymph and wingless adult stages) one day before chemical application. Four pots with individual seedlings were used for each treatment. A handheld aspirator sprayer was used to spray a solution onto both sides of the cabbage leaves until runoff. Reference plants (solvent check) were sprayed with the diluent only (0.025% Tween® 20 and 10% acetone / methanol (1:1) in water). Treated plants were kept in a holding room for three days at approximately 25°C and ambient relative humidity (RH) before grading. Grading was performed by counting live aphids per plant under a microscope three days post-treatment.The percentage control was measured using Abbott's correction formula (WS Abbott, “A Method of Computing the Effectiveness of an Insecticide” J. Econ. Entorno!. 18 (1925), pp.265-267) as follows. % of Corrected Control = 100 * (X - Y) / X IF-2019-63795218-APN-ANP#INPI Page 49 of 82 where X = number of live aphids on the plants for solvent testing and Y = number of live aphids on the treated plants. The results are presented in Table 2 below. Bioassay 2: Sweet potato whitefly (Tabaci. bemisia, BEMITA) (“SPW”). The sweet potato whitefly (SPW) is a major destructive pest of cotton. It is also a serious pest of many vegetable crops, including melons, cruciferous vegetables, tomatoes, and iceberg lettuce, as well as ornamental plants. SPW causes damage through direct feeding and virus transmission. As a sap-feeding insect, SPW depletes the plant of nutrients. This can lead to stunted growth, defoliation, reduced yields, and cotton drop. SPW produces large amounts of honeydew, which supports the growth of sooty mold on the plant's leaves. SPW is also a vector for viruses, such as cotton leaf curl virus and tomato yellow leaf curl virus. The Formula One test solutions and comparative examples, prepared as described above, were analyzed against SPW using the following procedure. Cotton seedlings grown in 3-inch pots, pruned to retain only one true leaf, were used as the test substrate. Adult B. tabaci were allowed to colonize these plants and lay eggs for 24 hours, after which all adults were removed from the plants using compressed air. The plants were monitored for egg development, and when caterpillar emergence began (>25% emergence based on visual examination using a microscope), the plants were sprayed using the solutions and test methods described above for green peach aphids (GPA). The treated plants were kept in a holding room at approximately 25°C and ambient relative humidity (RH) before grading. The evaluation was IF-2019-63795218-APN-ANP#iNPI Page 50 of 82 was performed by counting the number of 2-3 instar nymphs developed per plant under a microscope 7-9 days after treatment. The percentage control was measured using Abbott's correction formula (WS Abbott, "A Method of Computing the Effectiveness of an Insecticide" J. Econ. Entomol. 18 (1925), pp.265-267) as follows. % Corrected Control = 100 * (X - Y) / X where X = number of live nymphs on the plants for solvent testing and Y = number of live nymphs on the treated plants. The results are presented in Table 2 below. Bioassay analysis TABLE TWO Molecule # Bemisia tabaci # Myzus persicae LC50 mean PPM % LC5o mean PPM % IF-2019-63795218-APN-ANP#iNPI Page 51 of 82 • CE1 2 5.61 15 2 0.29 314 CE2 1 21.01 331 2 0.52 643 F1 2 4.87 6 0.07 CE3 2 25.35 421 3 0.05 -29 CE4 2 9.72 100 2 2.17 3000 Table 2 shows the bioassay results for F1, CE1, CE2, CE3, and CE4. The column number indicates the number of replicates for each bioassay. The median LC50 indicates parts per million. The % column shows the percentage increase in the median LC50 required. For example, in the Myzus persicae bioassays, comparing CE4 to F1, the percentage increase is ((2.17-0.07) / 0.07)*100 = 3000%, meaning that significantly more CE4 is needed compared to F1 to achieve the same effect. In light of the previous bioassays, the average percentage across all bioassays is 10 ((15+331+421+100+314+643+(-29)+3000) / 8), which is approximately 599%. This indicates that, on average, about 599% more pesticide is required to be as effective as F1. This is unexpected given the molecules tested. Addition salts of acids, salt derivatives, solvates, ester derivatives, 15 polymorphs, isotopes and radionuclides acceptable in agriculture. Formula One can be formulated as addition salts of acids acceptable in agriculture. By way of non-limiting example, an amine functional group can form salts with hydrochloric, hydrobromic, sulfuric, phosphoric, acetic, benzoic, citric, malonic, salicylic, malic, fumaric, oxalic, succinic, tartaric, lactic, and gluconic acids. IF-2019-63795218-APN-ANP#INPI Page 52 of 82 ascorbic, maleic, aspartic, benzenesulfonic, methanesulfonic, ethanesulfonic, hydroxymethanesulfonic and hydroxyethanesulfonic. Formula One can be formulated as salt derivatives. By way of non-limiting example, a salt derivative can be prepared by contacting a free base with a sufficient quantity of the desired acid to produce a salt. A free base can be regenerated by treating the salt with a suitable dilute aqueous base solution such as dilute aqueous sodium hydroxide, potassium carbonate, ammonia, or sodium bicarbonate. As an example, in many cases, a pesticide, such as 2,4-D, becomes more water-soluble when converted to its dimethylamine salt. Formula One compounds can be formulated as stable complexes with a solvent, such that the complex remains intact after the uncomplexed solvent is removed. These complexes are often called solvates. However, it is particularly convenient to form stable hydrates with water as the solvent. Formula One compounds can be produced as various crystalline polymorphs. Polymorphism is important in the development of agrochemical compounds because different crystalline polymorphs or structures of the same molecule can have very different physical properties and biological performance. Formula One molecules can be produced with different isotopes. Of particular importance are those containing 2H (also known as deuterium) or H₂O (also known as tritium) instead of 1H. Formula One molecules can also be obtained with different radionuclides. Of particular importance are those containing 14C (also known as radiocarbon). Formula One molecules containing deuterium, tritium, or 14C can be used in biological studies to enable tracking of chemical and physiological processes, half-life studies, and MoA studies. Combinations IF-2019-63795218-APN-ANP#INPI Page 53 of 82 In another embodiment of this invention, Formula One can be used in combination (such as in a mixture of compositions, or a simultaneous or sequential application) with one or more active ingredients. In another embodiment of this invention, Formula One can be used in combination (such as in a mixture of compositions, or a simultaneous or sequential application) with one or more active ingredients, each of which has a MoA that is the same as, similar to, or preferably different from the MoA of Formula One. In another modality, Formula One can be used in combination (such as in a mixture of compositions, or a simultaneous or sequential application) with one or more molecules that have acaricidal, algicidal, avicidal, bactericidal, fungicidal, herbicidal, insecticidal, molluscicidal, nematicidal, rodenticidal and / or virucidal properties. In another form, Formula One can be used in combination (such as in a mixture of compositions, or a simultaneous or sequential application) with one or more molecules that are feeding inhibitors, bird repellents, chemosterilants, herbicide protectants, insect attractants, insect repellents, mammal repellents, mating disruptors, plant activators, plant growth regulators, plant health stimulators or promoters, nitrification inhibitors and / or synergists. In another modality, Formula One can also be used in combination (such as in a mixture of compositions, or a simultaneous or sequential application) with one or more biopesticides. In another formulation, combinations of Formula One and an active ingredient can be used in a wide variety of weight ratios within a pesticide composition. For example, in a two-component mixture, the weight ratios of Formula One to an active ingredient can be those shown in Table 3. However, in general, weight ratios lower than approximately 10:1 to approximately 1:10 are preferred. IF-2019-63795218-APN-ANP#INPI4 Page 54 of 82 The active ingredient ratio can also be represented as X:Y, where X is the parts by weight of a molecule of Formula One and Y is the parts by weight of the active ingredient. The numerical range of parts by weight for X is 0 < X ​​to 100, and the parts by weight for Y is 0 < Y < 100, as shown graphically in Table 4. As a non-exhaustive example, the weight ratio of Formula One to an active ingredient might be 20:1. IF-2019-63795218-APN-ANP#INPI Page 55 of 82 TABLE 4 active ingredient (Y) Parts by weight 100 Χ,γ 10 X,Y Χ,γ 5 X,Y Χ,γ χ,γ Χ,γ 3 Χ,γ Χ,γ Χ,γ Χ,γ Χ,γ Χ,γ Χ,γ Χ,γ Χ,γ 1 2 3 5 10 15 20 50 100 Formula One, also known as F1, (X) Parts by weight The weight ratio ranges of Formula One with respect to an active ingredient can be represented as X1.Y1 to X2.Y2, where X and Y are defined as above. In one modality, the range of weight ratios can be X7:Y1 to X2Ύ2, where X1 > Y1 and X2 < Y2. As a non-limiting example, the range of a Formula One weight ratio with respect to an active ingredient can be between 3:1 and 1:3, inclusive of extreme values. IF-2019-63795218-APN-ANP#InPI Page 56 of 82 In another form, the weight ratio range can be X / Yj to X?. Y2, where X1> Y1 and X2> Y?. As a non-limiting example, the weight ratio range of Formula One with respect to an active ingredient can be between 15:1 and 3:1, inclusive of extreme values. In another form, the weight ratio range can be Xf:Y7 to X2:Y21 where Xf < Y, and X2 < Y2. As a non-limiting example, the weight ratio range of Formula One with respect to an active ingredient can be between approximately 1:3 and approximately 1:20, inclusive of extreme values. Formulations Often, a pesticide is not suitable for application in its pure form. It is generally necessary to add other substances so that the pesticide can be used at the required concentration and in a suitable form, allowing for easy application, handling, transport, storage, and maximum pesticidal activity. Therefore, pesticides are formulated, for example, as baits, concentrated emulsions, powders, emulsifiable concentrates, fumigants, gels, granules, microencapsulations, seed treatments, suspension concentrates, suspensions, tablets, water-soluble liquids, water-dispersible granules or dry fluids, wettable powders, and ultra-low volume solutions. Pesticides are commonly applied as aqueous suspensions or emulsions prepared from concentrated formulations of those pesticides. Such water-soluble, emulsifiable, or water-suspended formulations can be solids, generally known as wettable powders or water-dispersible granules; liquids, generally known as emulsifiable concentrates; or aqueous suspensions. Wettable powders, which can be compacted to form water-dispersible granules, comprise a close mixture of the pesticide, a carrier, and surfactants. The pesticide concentration is typically IF-2019-63795218-APN-ANP#lNPl Page 57 of 82 The carrier is generally selected from attapulgite clays, montmorillonite clays, diatomaceous earth, or purified silicates, comprising approximately 0.5% to approximately 10% of the wettable powder. Effective surfactants include sulfonated lignins, condensed naphthalenesulfonates, naphthalenesulfonates, alkylbenzenesulfonates, alkyl sulfates, and nonionic surfactants such as ethylene oxide adducts of alkylphenols. Emulsifiable pesticide concentrates comprise a convenient concentration of a pesticide, such as approximately 50 to approximately 500 grams per liter of liquid, dissolved in a vehicle that is either a water-miscible solvent or a mixture of a water-immiscible organic solvent and emulsifiers. Useful organic solvents include aromatic compounds, especially xylenes, and petroleum fractions, particularly high-boiling naphthalene and olefinic portions of petroleum such as heavy aromatic naphtha. Other organic solvents may also be used, such as terpene solvents including rosin derivatives, aliphatic ketones such as cyclohexanone, and complex alcohols such as 2-ethoxyethanol. Suitable emulsifiers for emulsifiable concentrates are selected from conventional anionic and nonionic surfactants. Aqueous suspensions comprise suspensions of water-insoluble pesticides dispersed in an aqueous vehicle at a concentration ranging from approximately 5% to approximately 50% by weight. Suspensions are prepared by finely grinding the pesticide and vigorously mixing it into a carrier composed of water and surfactants. Ingredients such as inorganic salts and synthetic or natural gums may also be added to increase the density and viscosity of the aqueous vehicle. It is often more efficient to grind and mix the pesticide simultaneously by preparing the aqueous mixture and homogenizing it in an instrument such as a sand mill, ball mill, or homogenizer. IF-2019-63795218-APN-ANP#INÉP Page 58 of 82 piston type. The pesticide in suspension could be microencapsulated in a plastic polymer. Oily dispersions (ODs) comprise suspensions of pesticides insoluble in organic solvents, finely dispersed in a mixture of organic solvent and emulsifiers at a concentration ranging from approximately 2% to approximately 50% by weight. One or more pesticides may be soluble in the organic solvent. Useful organic solvents include aromatic compounds, especially xylenes, and petroleum fractions, particularly high-boiling naphthalene and olefinic portions of petroleum such as heavy aromatic naphtha. Other solvents may include vegetable oils, seed oils, and esters of vegetable and seed oils. Suitable emulsifiers for oily dispersions are selected from conventional anionic and nonionic surfactants.Thickeners or gelling agents are added to the formulation of oily dispersions to modify the rheology or flow properties of the liquid and to prevent the separation and sedimentation of the dispersed particles or droplets. Pesticides can also be applied as granular compositions, which are particularly useful for soil applications. Granular compositions typically contain from approximately 0.5% to approximately 10% by weight of the pesticide, dispersed in a carrier comprising clay or a similar substance. Such compositions are usually prepared by dissolving the pesticide in a suitable solvent and applying it to a granular vehicle, which has been preformed to the appropriate particle size, in the range of approximately 0.5 mm to approximately 3 mm. Such compositions can also be formulated by obtaining a mass or paste of the vehicle and the pesticide molecule, and then grinding and drying it to obtain the desired granular particle size. Another form of granules is a water-emulsifiable (EG) granule. This is a formulation consisting of granules for application as a conventional oil-in-water emulsion of the ingredient(s). IF-2019-63795218-APN-ANP#INPI Page 59 of 82 active ingredients, solubilized or diluted in an organic solvent, after disintegration and dissolution in water. Water-emulsifiable granules comprise one or more active ingredients solubilized or diluted in a suitable organic solvent that are absorbed into a water-soluble polymer shell or some other type of soluble or insoluble matrix. Pesticide-containing powders are prepared by closely mixing the pesticide powder with a suitable powdered agricultural carrier, such as kaolin clay, volcanic rock soil, and similar materials. The powders can contain from approximately 1% to approximately 10% of the pesticide. They can be applied as a seed coating or as a foliar application using a powder blower. It is equally practical to apply a pesticide in the form of a solution in an appropriate organic solvent, usually petroleum oil, such as aerosol oils, which are widely used in agricultural chemistry. Pesticides can also be applied as an aerosol composition. In such compositions, the pesticide is dissolved or dispersed in a vehicle, which is a propellant mixture that generates pressure. The aerosol composition is packaged in a container from which the mixture is dispensed through a spray valve. Pesticide baits are formed when the pesticide is mixed with food, an attractant, or both. When pests ingest the bait, they also consume the pesticide. Baits can take the form of granules, gels, flowable powders, liquids, or solids. Baits can be used in pest shelters. Fumigants are pesticides with a relatively high vapor pressure and can therefore exist as a gas in concentrations sufficient to eliminate pests in soil or enclosed spaces. The toxicity of a fumigant is proportional to its concentration and the duration of exposure. They are characterized by a good capacity IF-2019-63795218-APN-ANP#INPI Page 60 of 82. Fumigants are diffused and act by penetrating the pest's respiratory system or being absorbed through the pest's cuticle. They are applied to control pests in products stored under gas-tight sheets, in gas-sealed rooms or buildings, or in special chambers. Pesticides can be microencapsulated by suspending pesticide particles or droplets in various types of polymers. By altering the polymer chemistry or changing processing factors, microcapsules of varying sizes, solubilities, wall thicknesses, and degrees of penetrability can be formed. These factors govern the rate at which the active ingredient is released, which in turn affects the product's residual performance, speed of action, and odor. Microcapsules can be formulated as suspension concentrates or water-dispersible granules. Oil-based pesticide concentrates are made by dissolving pesticide in a solvent that keeps the pesticide in solution. Oil-based pesticide solutions typically provide greater pest reduction and elimination than other formulations because the solvents themselves have pesticidal properties, and dissolving the wax coating of the insect's integument increases the rate of pesticide absorption. Other advantages of oil-based solutions include better storage stability, improved crack penetration, and better adhesion to oily surfaces. Another embodiment is an oil-in-water emulsion, wherein the emulsion comprises oil globules, each of which is provided with a lamellar liquid crystalline coating and dispersed in an aqueous phase, wherein each oil globule comprises at least one molecule that is agriculturally active and is individually coated with a monolaminar or oligolaminar layer comprising: (1) at least one non-ionic lipophilic surfactant, (2) at least one non-ionic hydrophilic surfactant, and (3) at least one ionic surfactant, wherein the globules have a mean particle diameter of less than 800 nanometers. IF-2019-63795218-APN-ANP#iNPi Page 61 of 82 Other components of the formulation Generally, when Formula One is used in a formulation, that formulation may also contain other components. These components include, but are not limited to (this is a non-exhaustive and non-exclusive list), wetting agents, spreaders, adhesives, penetrants, buffers, sequestering agents, drift-reducing agents, compatibility agents, antifoaming agents, cleaning agents, and emulsifiers. Some of these components are listed below. A wetting agent is a substance that, when added to a liquid, increases the liquid's penetrating or dispersing power by reducing the interfacial tension between the liquid and the surface on which it is dispersed. Wetting agents are used for two main functions in agrochemical formulations: during processing and manufacturing to increase the rate of wetting of powders in water to obtain liquid-soluble concentrates or suspension concentrates; and during the mixing of a product with water in a spray tank to reduce the wetting time of wettable powders and to improve water penetration into water-dispersible granules. Examples of wetting agents used in formulations of wettable powders, suspension concentrates, and water-dispersible granules include sodium lauryl sulfate, sodium dioctyl sulfosuccinate, alkylphenol ethoxylates, and aliphatic alcohol ethoxylates. A dispersing agent is a substance that adsorbs onto the surface of particles, helps preserve their dispersed state, and prevents reaggregation. Dispersing agents are added to agrochemical formulations to facilitate dispersion and suspension during manufacturing and to ensure that particles redisperse in water during spraying. They are widely used in wettable powders, suspension concentrates, and water-dispersible granules. Surfactants used as dispersing agents have the ability to adsorb strongly onto a particle surface and provide steric barriers. IF-2019-63795218-APN-ANP#iNPI Page 62 of 82 or charged for the new aggregation of the particles. The most commonly used surfactants are anionic, nonionic, or mixtures of both types. For wettable powder formulations, the most common dispersing agents are sodium lignosulfonates. For suspension concentrates, very good adsorption and stability are obtained with the use of polyelectrolytes, such as sodium-naphthalene-sulfonate-formaldehyde condensates. Tristyrylphenol ethoxylate phosphate esters are also used. Nonionic surfactants such as alkylarylethylene oxide condensates and EO-PO block copolymers are sometimes combined with anionic agents as dispersants for suspension concentrates. In recent years, new types of very high molecular weight polymeric surfactants have been developed as dispersing agents.These have very long hydrophobic backbones and a large number of ethylene oxide chains that form the teeth of a comb surfactant. These high molecular weight polymers can provide very good long-term stability to suspension concentrates because the hydrophobic backbones have many anchoring points on the particle surfaces. Examples of dispersing agents used in agrochemical formulations include: sodium lignosulfonates, sodium naphthalene sulfonate condensates and formaldehyde, tristyrylphenol ethoxylate phosphate esters, aliphatic alcohol ethoxylates, alkyl ethoxylates, EO-PO block copolymers, and graft copolymers. An emulsifying agent is a substance that stabilizes a suspension of droplets of one liquid phase in another liquid phase. Without the emulsifying agent, the two liquids would separate into two immiscible liquid phases. The most common emulsifying mixtures contain an alkylphenol or an aliphatic alcohol with twelve or more ethylene oxide units and the oil-soluble calcium salt of dodecylbenzenesulfonic acid. A hydrophilic-lipophilic equilibrium (HLB) range of approximately 8 to approximately 18 will typically provide emulsions with good stability. IF-2019-63795218-APN-ANP#lNPI Page 63 of 82 The stability of the emulsion can sometimes be improved by adding a small amount of an EO-PO block copolymer surfactant. A solubilizing agent is a surfactant that will form micelles in water at concentrations above the critical micelle concentration. These micelles are then able to dissolve or solubilize water-insoluble materials within their hydrophobic portion. Commonly used surfactants for solubilization include nonionic surfactants, sorbitan monooleates, sorbitan monooleate ethoxylates, and methyl oleate esters. Surfactants are sometimes used, either alone or with other additives such as mineral or vegetable oils, as adjuvants in spray tank mixtures to improve the biological performance of the pesticide on the target. The types of surfactants used for biological enhancement generally depend on the nature and mode of action of the pesticide. However, they are frequently nonionic, such as alkyl ethoxylates, linear aliphatic alcohol ethoxylates, and aliphatic amine ethoxylates. A carrier or diluent in an agricultural formulation is a material added to the pesticide to produce a product of the required strength. Carriers are typically materials with high absorption capacity, while diluents are typically materials with low absorption capacity. Carriers and diluents are used in the formulation of powders, wettable powders, granules, and water-dispersible granules. Organic solvents are primarily used in the formulation of emulsifiable concentrates, oil-in-water emulsions, suspensions, oil dispersions, and ultra-low volume formulations, and to a lesser extent, granular formulations. Sometimes solvent mixtures are used. The first major group of solvents consists of aliphatic paraffinic oils such as kerosene or refined paraffins. The second major group (and the most common) comprises aromatic solvents such as xylene and higher molecular weight fractions of IF-2019-63795218-APN-ANP#JNPI Page 64 of 82 Aromatic C9 and C10 solvents. Chlorinated hydrocarbons are useful as cosolvents to prevent pesticide crystallization when the formulation is emulsified in water. Alcohols are sometimes used as cosolvents to increase solvent power. Other solvents may include vegetable oils, seed oils, and esters of vegetable and seed oils. Thickeners or gelling agents are primarily used in the formulation of suspension concentrates, emulsions, and suspoemulsions to modify the rheology or flow properties of the liquid and prevent the separation and sedimentation of dispersed particles or droplets. Thickening, gelling, and anti-sedimentation agents are generally divided into two categories: water-insoluble particulates and water-soluble polymers. It is possible to produce suspension concentrate and oil-dispersion formulations using clays and silicas. Examples of these materials include, but are not limited to, montmorillonite, bentonite, magnesium aluminum silicate, and attapulgite. Water-soluble polysaccharides have been used as thickening and gelling agents in aqueous suspension concentrates for many years.The most commonly used types of polysaccharides are natural extracts from seeds and algae or synthetic derivatives of cellulose. Examples of these materials include, but are not limited to, guar gum, locust bean gum, carrageenan, alginates, methyl cellulose, sodium carboxymethyl cellulose (SCMC), and hydroxyethyl cellulose (HEC). Other types of anti-sedimentation agents are based on modified starches, polyacrylates, polyvinyl alcohol, and polyethylene oxide. Xanthan gum is another good anti-sedimentation agent. Microorganisms can cause spoilage in formulated products. Therefore, preservatives are used to eliminate or reduce their effect. Examples of such agents include, but are not limited to: propionic acid and its sodium salt, sorbic acid and its sodium or potassium salts, benzoic acid and its sodium salt, sodium salt of p-hydroxybenzoic acid, methyl p-hydroxybenzoate, and 1,2-benzisothiazolin-3-one (BIT). IF-2019-63795218-APN-ANP#INgI Page 65 of 82 The presence of surfactants frequently causes aqueous formulations to foam during mixing operations in production and during application via a spray tank. To reduce foaming, antifoaming agents are often added during the production stage or before filling the bottles. Generally, there are two types of antifoaming agents: silicones and non-silicones. Silicones are typically aqueous emulsions of dimethyl polysiloxane, while non-siliconed antifoaming agents are water-insoluble oils, such as octanol and nonanol, or silica. In both cases, the function of the antifoaming agent is to displace the surfactant from the air-water interface. “Green” agents (e.g., adjuvants, surfactants, solvents) can reduce the overall environmental footprint of crop protection formulations. Green agents are biodegradable and generally originate from natural and / or sustainable sources, such as plants and animals. Specific examples include vegetable oils, seed oils and their esters, as well as alkoxylated alkyl polyglucosides. Applications Formula One can be applied to any locus. Specific loci for applying such molecules include those where alfalfa, almonds, apples, barley, beans, canola, corn, cotton, cruciferous vegetables, flowers, forage species (ryegrass, Sudan grass, tall fescue, meadow bluegrass, and clover), fruits, lettuce, oats, oilseed crops, oranges, peanuts, pears, peppers, potatoes, rice, sorghum, soybeans, strawberries, sugarcane, sugar beets, sunflowers, tobacco, tomatoes, wheat (e.g., hard red winter wheat, soft red winter wheat, white winter wheat, hard red spring wheat, and durum spring wheat), and other valuable crops are grown or where their seeds are to be planted. IF-2019-63795218-APN-ANP#INPI Page 66 of 82 Formula One can also be applied wherever plants are grown, such as in crops, and where there are low levels (or even a complete absence) of pests that could commercially damage those plants. Applying such molecules to these locations is beneficial to the plants grown there. These benefits may include, but are not limited to: helping the plant develop a better root system; helping the plant better withstand stressful growing conditions; improving plant health; improving plant yield (e.g., increased biomass and / or increased content of valuable ingredients); improving plant vigor (e.g., improved plant growth and / or greener leaves); improving plant quality (e.g., improved content or composition of certain ingredients); and improving the plant's tolerance to abiotic and / or biotic stress. Formula One can be applied with ammonium sulfate when growing various plants as this can provide additional benefits. Formula One can be applied on, in, or around plants genetically modified to express specialized traits, such as Bacillus thuringiensis toxins (e.g., CrylAb, CrylAc, CrylFa, Cry1A.1O5, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb, Cry34Ab1 / Cry35Ab1), other insecticidal toxins, or those expressing herbicide tolerance, or those with stacked foreign genes expressing insecticidal toxins, herbicide tolerance, improved nutrition, or any other beneficial trait. Formula One can be applied to the leaves and / or fruit of plants to control pests. These molecules will either come into direct contact with the pest, or the pest will consume them when it ingests the plant or while extracting sap or other nutrients from it. Formula One can also be applied to the soil, and when applied in this way, it can control pests that feed on stems and roots. IF-2019-63795218-APN-ANP#FNpI Page 67 of 82 roots can absorb such molecules, thus carrying them to the leafy parts of the plant to control chewing and sap-feeding pests above ground. The systemic movement of pesticides in plants can be used to control pests in one part of the plant by applying (for example, spot spraying) a Formula One molecule to a different part of the plant. For example, control of leaf-feeding insects can be achieved by drip irrigation or furrow application, by treating the soil (for example, by impregnating the soil before or after planting), or by treating a plant's seeds before sowing. Formula One can be used with baits. Generally, with baits, the baits are placed on the ground where, for example, termites can come into contact with the bait and / or be attracted to it. Baits can also be applied to a building surface (horizontal, vertical, or sloping) where, for example, ants, termites, cockroaches, and flies can come into contact with the bait and / or be attracted to it. Formula One can be encapsulated within a capsule or placed on its surface. The size of the capsules can vary from nanometric (approximately 100-900 nanometers in diameter) to micrometric (approximately 10-900 micrometers in diameter). Formula One can be applied to pest eggs. Due to the unique ability of some pest eggs to resist certain pesticides, repeated applications of such molecules may be beneficial for controlling newly hatched larvae. Formula One can be applied as a seed treatment. Seed treatment can be applied to all types of seeds, including those from which genetically modified plants will germinate to express specialized traits. Representative examples include those that express proteins toxic to pests. IF-2019-63795218-APN-ANP#lNPl Page 68 of 82 Seeds treated with Formula One can be modified to contain invertebrates, such as Bacillus thuringiensis or other insecticidal toxins; herbicide tolerance, such as that expressed in “Roundup Ready” seeds; or seeds with “stacked” foreign genes that express insecticidal toxins, herbicide tolerance, improved nutrition, drought tolerance, or any other beneficial trait. Furthermore, such seed treatments can further enhance a plant's ability to withstand stressful growing conditions. This results in a healthier, more vigorous plant, which can lead to higher yields at harvest time.Generally, amounts of approximately 0.0025 mg of Formula One per seed to approximately 2.0 mg of Formula One per seed are useful; amounts of approximately 0.01 mg of Formula One per seed to approximately 1.75 mg of Formula One per seed are useful; amounts of 0.1 mg of Formula One per seed to approximately 1.5 mg of Formula One per seed are useful; and amounts of 0.25 mg of Formula One per seed to approximately 0.75 mg of Formula One per seed are useful. In general, an amount of approximately 0.5 mg of Formula One per seed is useful. Formula One can be applied with one or more active ingredients in a soil amendment. Formula One can be used to control endoparasites and ectoparasites in veterinary medicine or in the field of non-human animal conservation. These molecules can be administered orally in the form of tablets, capsules, drinks, or granules; dermalally through methods such as immersion, spraying, pouring, spot-on application, or dusting; and parenterally, for example, by injection. Formula One can also be advantageously used in livestock farming, for example, cattle, chickens, geese, goats, pigs, sheep, and turkeys. It can also be advantageously used with domestic animals such as horses, dogs, and cats. Particular pests for its control would be flies, fleas, and ticks, which are IF-2019-63795218-APN-ANP#INPI Page 69 of 82. These formulations are bothersome to these animals. Suitable formulations are administered orally to the animals with their drinking water or feed. The appropriate dosages and formulations depend on the species. Formula One can also be used to control parasitic worms, especially intestinal worms, in the animals mentioned above. Formula One can also be used in therapeutic methods for human health care. Such methods include, but are limited to, oral administration, for example, in the form of tablets, capsules, drinks, granules, and through dermal application. Formula One can also be applied to invasive pests. Pests worldwide have been migrating to new environments (for that particular pest) and then becoming a new invasive species in that new environment. Such molecules can also be used on these new invasive species to control them in these new environments. Plant viruses cause an estimated $60 billion USD in crop yield losses worldwide each year. Many plant viruses must be transmitted by a vector, most often insects, such as leafhoppers and fulgoromorphs. However, nematodes have also been shown to transmit viruses. Nematodes transmit plant viruses by feeding on roots. Formula One can also be applied to a plant to inhibit pests that carry plant viruses, thus reducing the possibility of these viruses being transmitted from the pest to the plant. Accordingly, in light of the above, the following additional, non-exhaustive details (D) are provided. 1D. A molecule that has the following formula IF-2O19-63795218-APN-ANP#INPI Page 70 of 82 Formula One also known as F1 and N-oxides, acid addition salts acceptable in agriculture, salt derivatives, solvates, ester derivatives, polymorphs, isotopes, resolved stereoisomers and / or tautomers, of these. 2D. A composition comprising a molecule according to 1D and further comprising a carrier. 3D. A composition according to 2D, said composition further comprising an active ingredient. 4D. A composition according to any of the above details, said composition further comprising an active ingredient selected from acaricides, algaecides, feeding inhibitors, avicides, bactericides, bird repellents, chemosterilants, fungicides, herbicide protectants, herbicides, insect attractants, insect repellents, insecticides, mammal repellents, mating disruptors, molluscicides, nematicides, plant activators, plant health stimulators or promoters, nitrification inhibitors, plant growth regulators, rodenticides, synergists, and virucides. 5D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from AIGA. IF-2019-63795218-APN-ANP#INPl Page 71 of 82 6D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from AI-1. 7D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from AI-2. 8D. A composition in accordance with any of the above details, said composition further comprising Lotilaner. 9D. A composition in accordance with any of the above details, said composition further comprising a molecule selected from Table A. 10D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from AIGA-2. 11D. A composition in accordance with any of the above details, said composition further comprising a biopesticide. 12D. A composition according to any of the above details, said composition further comprising an active ingredient selected from acetylcholinesterase (AChE) inhibitors. 13D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from GABA-dependent chloride channel antagonists. IF-2019-63795218-APN-ANP#INPI Page 72 of 82 14D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from sodium channel modulators. 15D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from nicotinic acetylcholine receptor (nAChR) agonists. 16D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from the allosteric activators of nicotinic acetylcholine receptors (nAChR). 17D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from chloride channel activators. 18D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from the youth hormone mimetics. 19D. A composition in accordance with any of the above details, said composition further comprising an active ingredient of the miscellaneous non-specific (multi-site) inhibitors. 20D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from modulators of the chordotonal organs. IF-2019-63795218-APN-ANP#INPI Page 73 of 82 21D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from mite growth inhibitors. 22D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from the microbial disruptors of the midgut membranes of insects. 23D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from the inhibitors of mitochondrial ATP synthesis. 24D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from proton gradient disruption uncouplers of oxidative phosphorylation. 25D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from nicotinic acetylcholine receptor (nAChR) channel blockers. 26D. A composition according to any of the above details, said composition further comprising an active ingredient selected from chitin biosynthesis inhibitors, type 0. IF-2019-63795218-APN-ANP#INPI Page 74 of 82 27D. A composition according to any of the above details, said composition further comprising an active ingredient selected from chitin biosynthesis inhibitors, type 1. 28D. A composition according to any of the above details, said composition further comprising an active ingredient selected from molt disruptors, Diptera 29D. A composition according to any of the above details, said composition further comprising an active ingredient selected from ecdysone receptor agonists. 30D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from octopamine receptor 15 agonists. 31D. A composition according to any of the above details, said composition further comprising an active ingredient selected from the mitochondrial complex III electron transport inhibitors 32D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from mitochondrial complex I electron transport inhibitors. 33D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from voltage-gated sodium channel blockers. IF-2019-63795218-APN-ANP#INBI Page 75 of 82 34D. A composition according to any of the above details, said composition further comprising an active ingredient selected from the acetyl CoA carboxylase inhibitors 35D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from the inhibitors of mitochondrial complex IV electron transport. 36D. A composition according to any of the above details, said composition further comprising an active ingredient selected from mitochondrial complex II electron transport inhibitors. 37D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from the ryanodine receptor modulators. 38D. A composition in accordance with any of the above details, said composition further comprising an active ingredient selected from Group UN. 39D. A composition according to any of the above details, said composition further comprising chlorantraniliprole. 40D. A composition according to any of the above details, said composition comprising chlorpyrifos. 41D. A composition in accordance with any of the above details, said composition further comprising cyantraniliprole. IF-2019-63795218-APN-ANP#INPI Page 76 of 82 42D. A composition according to any of the above details, said composition further comprising methomyl. 43D. A composition according to any of the above details, said composition further comprising methoxyfenozide. 44D. A composition in accordance with any of the above details, said composition further comprising oxamyl. 45D. A composition in accordance with any of the above details, said composition further comprising espinetoram. 46D. A composition in accordance with any of the above details, said composition further comprising spinosad. 47D. A composition in accordance with any of the above details, said composition further comprising sulfoxaflor. 48D. A composition according to any of the above details, said composition further comprising triflumezopirim. 49D. A composition in accordance with any of the above details, said composition further comprising oeta-cyfluthrin. 50D. A composition in accordance with any of the above details, said composition further comprising clothianidin. IF-2019-63795218-APN-ANP#im Page 77 of 82 51D. A composition in accordance with any of the above details, said composition further comprising cyfluthrin. 52D. A composition in accordance with any of the above details, said composition further comprising flubendiamide. 53D. A composition in accordance with any of the above details, said composition further comprising fluopyram. 54D. A composition in accordance with any of the above details, said composition further comprising flupyradifurone. 55D. A composition according to any of the above details, said composition further comprising imidacloprid. 56D. A composition according to any of the above details, said composition further comprising spiromesifen. Yo 57D. A composition according to any of the above details, said composition further comprising spirotetramat. 58D. A composition in accordance with any of the above details, said composition further comprising spirodiclofen. 59D. A composition according to any of the above details, said composition further comprising tetraniliprol. IF-2019-63795218-APN-ANP#IW Page 78 of 82 60D. A composition in accordance with any of the above details, said composition further comprising thiodicarb. 61D. A composition according to any of the above details, said composition further comprising thiacloprid. 62D. A composition in accordance with any of the above details, said composition further comprising a / fa-cypermethrin. 63D. A composition according to any of the above details, said composition further comprising cyflumethofen. 64D. A composition in accordance with any of the above details, said composition further comprising fipronil. 65D. A composition in accordance with any of the above details, said composition further comprising metaflumizone. 66D. A composition in accordance with any of the above details, said composition further comprising zefa-cypermethrin. 67D. A composition in accordance with any of the above details, said composition further comprising aphidopyropen. 68D. A composition in accordance with any of the above details, wherein the weight ratio of F1 to an active ingredient is 100:1 to 1:100. IF-2019-63795218-APN-ANP#INPI Page 79 of 82 69D. A composition in accordance with any of the above details, wherein the weight ratio of F1 to an active ingredient is 50:1 to 1:50. 70D. A composition in accordance with any of the above details, wherein the weight ratio of F1 to an active ingredient is 20:1 to 1:20. 71D. A composition in accordance with any of the above details, wherein the weight ratio of F1 to an active ingredient is 10:1 to 1:10. 72D. A composition in accordance with any of the above details, wherein the weight ratio of F1 to an active ingredient is 5:1 to 1:5. 73D. A composition in accordance with any of the above details, wherein the weight ratio of F1 to an active ingredient is 3:1 to 1:3. 74D. A composition in accordance with any of the above details, wherein the weight ratio of F1 to an active ingredient is 2:1 to 1:2. 75D. A composition in accordance with any of the above details, wherein the weight ratio of F1 to an active ingredient is 1:1. 76D. A composition in accordance with any of the details wherein the weight ratio of F1 to the active ingredient is X.Ύ; where X are the weight parts of F1 and Y are the weight parts of an active ingredient; wherein further the numerical range of weight parts for X is 0 < X ​​is 100 and the weight parts for Y is 0 < Y < 100; and further wherein X and Y are selected from Table 4. DF-2019-63795218-APN-ANP#DNPD Page 80 of 82 77D. A process for controlling a pest, said process comprising: applying to a locus a pesticidal quantity of the composition comprising F1. 78D. A process for controlling a pest, said process comprising applying to a locus, a pesticidal quantity of a composition in accordance with any of the details above 2D to 76D. 79D. A process in accordance with any of the details in 77D or 78D wherein such pest is selected from the group consisting of ants, aphids, bed bugs, beetles, springtails, caterpillars, cockroaches, crickets, earwigs, fleas, flies, grasshoppers, larvae, cicadas, lice, locusts, worms, mealybugs, mites, nematodes, leafhoppers, psyllids, sawflies, scale insects, silverfish, slugs, snails, spiders, springtails, stink bugs, symphylans, termites, spider mites, ticks, wasps, whiteflies, and elaterids. 80D. A process in accordance with any of the details 77D or 78D where said pest is a sap-feeding pest. 81D. A process in accordance with details 77D or 78D where said pest is an aphid. 82D. A process in accordance with details 77D or 78D where said plague is a fulgoromorph. 83D. A process in accordance with details 77D or 78D where said pest is of the Order Anoplura or Hemiptera. IF-2019-63795218-APN-ANP#iNPI Page 81 of 82 84D. A process in accordance with details 77D or 78D, wherein said composition is applied to the soil. 85D. A process in accordance with details 77D or 78D wherein said composition 5 is applied to the foliar parts of a plant. 86D. A process in accordance with details 77D or 78D where said locus rice, corn, soybeans, cotton, potato, sorghum, sugarcane, canola, tea, grapes, wheat, barley, alfalfa or other fruits or vegetables are growing. 87D. A composition in accordance with any of the details above 2D to 76D, said composition further comprising a seed. 88D. A composition according to detail 87D, wherein said seed is a 15 cottonseed, sunflower seed, rice seed, beet seed, rapeseed, corn seed, wheat seed, barley seed, millet seed, sorghum seed, buckwheat seed, oat seed, rye seed, soybean seed or quinoa seed. 89D. A composition in accordance with detail 87D wherein approximately 0.0025 mg of Formula One per seed to approximately 2.0 mg of Formula One per seed is used. The headings in this document are for convenience only and should not be used to interpret any part of it. IF-2019-63795218-APN-ANP#INPI Page 82 of 82 Argentine Republic - National Executive Branch 2019 - Year of Exports Additional Signature Sheet Graphic Report Number: IF-2019-63795218-APN-ANP#INPI CITY OF BUENOS AIRES Monday, July 15, 2019 Reference: 20190101569 The document was imported by the GEDO system with a total of 82 page(s). Digitally signed by GESTION DOCUMENTAL ELECTRONICA - GDE DN: cn=ELECTRONIC DOCUMENTARY MANAGEMENT - GDE, c=AR, o=GOVERNMENT SECRETARY OF MODERNIZATION, ou=ADMINISTRATIVE MODERNIZATION SECRETARY, serialNumber=CUIT 30715117564 Date: 2019.07.15 11:01:26 -03'00' Mariela Flavia Gonnet Administrative Advisor National Patent Administration National Institute of Industrial Property Digitally signed by GESTION DOCUMENTAL ELECTRONICA GDE DN: cn=GEST10N ELECTRONIC DOCUMENTARY - GDE, c=AR, o=GOVERNMENT SECRETARY OF MODERNIZATION, ou=ADMINISTRATIVE MODERNIZATION SECRETARY, serialNumber=CUIT 30715117564 Date: 2019.07.15 11:01:27 -03'00'

Claims

1. A molecule, excluding its therapeutic application in humans, characterized in that it is N-(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-2-(methylsulfonyl)propanamide, having the following formula (Formula One): (FORMULA) and N-oxides, acid addition salts acceptable in agriculture, salt derivatives, solvates, ester derivatives, polymorphs, isotopes, resolved stereoisomers and tautomers, and radionuclides thereof. Claim 1 follows