Title - COSMETIC COMPOSITION FOR HAIR CARE, EXCLUDING ITS THERAPEUTIC USES

Abstract

A hair care composition comprising: a) a piroctone compound; and b) a cationic homopolymer and / or copolymer comprising an acrylamide propyltrimonium moiety wherein the homopolymer and / or copolymer has a charge density of at least 3.5 meq / g.

Description

DESCRIPTIVE MEMORANDUM Field of invention The present invention relates to a hair care composition, particularly an anti-dandruff shampoo composition. Background of the invention Hair care products typically provide cleansing or conditioning benefits, or a combination of both. These products usually contain one or more cleansing surfactants that help cleanse the hair and scalp, removing dirt, particles, and unwanted oils. Dandruff is a problem that affects many people worldwide. The condition manifests as the shedding of clumps of dead skin cells from the scalp. These flakes are white and create an unsightly appearance. One contributing factor to dandruff is certain members of the Malassezia yeast family. To combat these yeasts, hair treatment formulations are developed that include various active ingredients for their anti-dandruff efficacy. Piroctone, such as piroctone olamine, is one such active ingredient. A common problem with piroctone is that it is difficult to deposit onto the hair or scalp during washing. This is particularly true when effective anionic cleansing surfactants such as sodium laureth sulfate are present in the formula. During excessive rinsing, most of the piroctone is likely to be washed away with the surfactants. This poor deposition correlates with low anti-dandruff activity, and therefore, little mitigation of the harmful effects of dandruff. To date, efforts are underway to address this issue. 1418710 of 21 disadvantages: increasing the level of piroctone olamine in the hair treatment formulation. This approach causes several problems, such as increased costs, potential formulation instability, and a potential adverse effect on hair feel. Therefore, it is not a preferred approach by the industry. Cationic polymers are used to enhance the deposition of conditioning agents and / or anti-dandruff agents on the hair and / or scalp. These polymers can be synthetic or natural polymers modified with cationic substituents. The present invention relates to the improved deposition of a piroctone compound (Octopirox) using cationic polymers with a defined charge density. Description of the invention In one aspect, the present invention relates to a hair care composition comprising: a) a piroctone compound; and b) a homopolymer and / or copolymer comprising an acrylamide propyltrimonium moiety wherein the polymer and / or copolymer has a charge density of at least 3.5 meq / ga pH 7 and a weight-weight average molecular weight (g / mol) of 100,000 to 500,000. In a second aspect, the present invention relates to a cosmetic method for depositing anti-dandruff agents on the scalp, comprising the step of applying the hair care composition of any embodiment of the first aspect of this invention to the scalp surfaces of an individual. The method is for non-therapeutic benefits. 1418710 of 21 Detailed description of the invention The term "hair care composition" refers to compositions for topical application to the hair and / or scalp of mammals, especially humans. Such a composition can generally be classified as either leave-in or rinse-out. The composition of the present invention may be in the form of a liquid, lotion, cream, foam, scrub, gel, or bar. Non-restrictive examples of such compositions include leave-in hair lotions, creams, rinse-out shampoos, conditioners, shower gels, or bar soap. The composition of the present invention is preferably a rinse-out composition, especially preferably a shampoo or conditioner, and most preferably a shampoo. Cationic charge density refers to the number of cationic charges per unit weight of a given polymer. As used herein, the term charge density refers to the ratio of positive charges on a monomeric unit of which a polymer is composed to the molecular weight of that monomeric unit. The charge density multiplied by the molecular weight of the polymer determines the number of positively charged sites on a given polymer chain. Cationic charge density can be calculated from the degree of substitution described in WO 2013 / 011122, which is incorporated herein by reference in its entirety, but particularly on page 8, lines 8-17. The cationic charge density of the polymer can also be adequately determined by the Kjeldahl method as described in the United States Pharmacopeia under Chemical Tests for the Determination of Nitrogen and is expressed in milliequivalents (meq) per gram. The cationic charge density is determined at pH 7. 1418710 of 21 Insoluble in water refers to the solubility of a material in water at 25 °C and atmospheric pressure is 0.1% by weight or less. "Molecular weight" refers to the weight-average molecular mass of a given polymer. The weight-average molecular weight (WAVG MW) of a given polymer is determined by size-exclusion chromatography (SEC) analysis using absolute calibration (universal calibration). Pullulan and dextran polysaccharide standards were used for calibration. Except in the examples, or where explicitly stated otherwise, all numbers in this description that indicate quantities of material or reaction conditions, physical properties of materials and / or use may optionally be understood as modified by the word approximately. All quantities are by weight of the final hair care composition, unless otherwise specified. It should be noted that, when specifying any range of values, any particular upper value can be associated with any particular lower value. When a feature is disclosed with respect to a particular aspect of the invention (e.g., a composition of the invention), such disclosure should also be considered applicable to any other aspect of the invention (e.g., a method of the invention) mutatis mutandis. The polymer suitable for use in compositions of the present invention comprises acrylamide. Preferably, the copolymer also comprises acrylamide in addition to acrylamide. The particularly preferred copolymer is a copolymer of acrylamide and acrylamide. The polymer and / or copolymer according to the present invention has a charge density 1418710 of 21 of at least 3.5 meq / g, more preferably 4 meq / g with maximum preference of 4.3 to 5.3 meq / g pH 7. The homopolymer and / or copolymer preferably has a weight average molecular weight of 100,000 to 500,000, more preferably 150,000 to 400,000. An example of a suitable homopolymer is commercially available from Ashland under the trade name N-DurHance A-1000® (acrylamide trimethyl ammonium chloride cationic homopolymer). An example of a suitable copolymer is commercially available from Ashland under the trade name N-DurHance AA2000® (acrylamide copolymer acrylamide cationic copolymer). Typically, the cationic polymer is present at a level of 0.01 to 5% by weight of the total composition, preferably 0.05 to 2% by weight, more preferably 0.1 to 1% by weight. Additional cationic deposition polymers can be included, in addition to the homopolymer / copolymer, but are not preferred. The preferred formulation is an anti-dandruff shampoo. The anti-dandruff shampoo may appropriately comprise 50 to 90%, preferably 60 to 80%, water by weight of the total shampoo. Cleaning phase The cleansing phase comprises one or more cleansing surfactants. Cleansing surfactants are those that act to cleanse the hair and / or scalp. The total level of cleansing surfactants is preferably 3 to 45%, more preferably 5 to 25%, with a maximum preference of 7 to 20% by weight of the total composition. Preferably, the cleaning surfactant comprises an anionic surfactant. 1418710 of 21 anionic surfactant comprises an ethoxylated alkyl sulfate anionic surfactant. The preferred alkyl ether sulfates are those of formula (I): RO-(CH2CH2-O)n-SO3-M+(I) where R is a linear or branched alkyl chain having 8 to 18 (preferably 12 to 18) carbon atoms; n is the average degree of ethoxylation and ranges from 0.5 to 3 (preferably 1 to 3); and M is a solubilizing cation such as sodium, potassium, ammonium, or substituted ammonium. An example is sodium lauryl ether sulfate (SLES). The most preferred example is SLES having an average degree of ethoxylation of 0.5 to 3, preferably 1 to 3. The preferred level of such surfactant is 2 to 20% by weight of the total composition, more preferably 7 to 15% by weight. Other surfactants, such as alkyl sulfates, may be present in the composition. The preferred alkyl sulfates are C12-18 alkyl sulfates, more preferably C12-18 alkyl sulfates, preferably in the form of a salt with a solubilizing cation such as sodium, potassium, ammonium, or substituted ammonium. Examples include sodium lauryl sulfate (SLS) and sodium dodecyl sulfate (SDS). The cleansing phase may include one or more additional anionic surfactants that are cosmetically acceptable and suitable for topical application to the hair and / or scalp. Examples of additional anionic surfactants include alkaryl sulfonates, alkyl succinates, alkyl sulfosuccinates, alkyl ether sulfosuccinates, N-alkyl sarcosinates, alkyl phosphates, alkyl ether phosphates, and alkyl ether carboxylic acids and their salts, especially their sodium, magnesium, ammonium, and mono-, di-, and triethanolamine salts. Alkyl ether sulfosuccinates, alkyl ether phosphates, and alkyl ether carboxylic acids and their salts may contain from 1 to 20 ethylene oxide or propylene oxide units per molecule. 1418710 of 21 Typical anionic cleansing surfactants for use in shampoo compositions according to the present invention include sodium oleyl succinate, ammonium lauryl sulfosuccinate, sodium lauryl ether sulfosuccinate, sodium dodecylbenzenesulfonate, triethanolamine dodecylbenzenesulfonate, lauryl carboxylic acid and sodium N-lauryl sarcosinate, sodium lauryl monoglyceride sulfate, sodium lauryl sulfate, sodium laureth sulfate, sodium cocoyl sulfate, sodium cocoyl isethionate and mixtures thereof. The composition may include co-surfactants to help impart aesthetic, physical, or cleansing properties. The co-surfactant is preferably included in the cleansing phase of the composition. An example of a co-surfactant is a non-ionic surfactant, which may be included in an amount ranging from 0.5 to 10%, preferably from 2 to 8%, and more preferably from 1 to 5% by weight of the total composition. For example, representative nonionic surfactants that may be included in the treatment compositions, preferably the shampoo compositions of the invention, include condensation products of primary or secondary linear or branched aliphatic (Cs-Cs) alcohols or phenols with alkylene oxides, typically ethylene oxide, and with 6 to 30 ethylene oxide groups. Other representative nonionic surfactants include mono- or di-alkyl alkanolamides. Examples include coco-mono- or di-ethanolamide and coco-mono-isopropanolamide. Other nonionic surfactants that may be included are alkyl polyglycosides (APGs). An APG typically comprises an alkyl group connected (optionally via a bridging group) to a block of one or more glycosyl groups. Preferred APGs are defined by the following formula (II): R'O - (G)k (II) where R is a linear or branched chain alkyl group that can be1418710 of 21 saturated or unsaturated and G is a saccharide group. R' may represent an average alkyl chain length from approximately C5 to approximately C20. Preferably, R' represents an average alkyl chain length from approximately C8 to approximately C12. Most preferably, the value of R' is between approximately 9.5 and approximately 10.5. G may be selected from C5 or C6 monosaccharide residues and is preferably a glucoside. G may be selected from the group comprising glucose, xylose, lactose, fructose, mannose, and derivatives thereof. Preferably, G is glucose. The degree of polymerization, k, may have a value from approximately 1 to approximately 10 or more; preferably, the value of k is between approximately 1.1 and approximately 2; most preferably, the value of k is between approximately 1.3 and approximately 1.5.The alkylpolyglycosides suitable for use in the invention are commercially available and include, for example, those materials identified as: Oramix NS10 ex Seppic; Plantaren 1200 and Plantaren 2000 ex Henkel. Other sugar-derived nonionic surfactants that can be included in compositions (preferably shampoos) of the invention include C10-C18 N-alkyl (Ci-C6) polyhydroxy fatty acid amides, such as C12-C18 N-methylglucamides, as described, for example, in WO 92 / 06154 and US 5,194,639, and N-alkoxy polyhydroxy fatty acid amides, such as C10-C18 N-(3-methoxypropyl)glucamide. A preferred example of a co-surfactant is an amphoteric or zwitterionic surfactant, which can be included in an amount ranging from 0.5 to approximately 10% by weight, preferably 2 to 8, more preferably 1 to 5% by weight of the total composition. 1418710 of 21 Examples of amphoteric or zwitterionic surfactants include alkyl amine oxides, alkyl betaines, alkylamidopropyl betaines, alkyl sulfobetaines (sultains), alkyl glycinates, alkyl carboxyglycinates, alkyl amphoacetates, alkyl amphopropionates, alkylphoglycinates, alkylamidopropyl hydroxysultains, acyl taurates, and acyl glutamates, where the alkyl and acyl groups have from 8 to 22 carbon atoms. Typical amphoteric and zwitterionic surfactants for use in shampoos of the invention include laurylamine oxide, cocodimethyl sulfopropyl betaine, lauryl betaine, cocamidopropyl betaine, and sodium cocoamphoacetate. A particularly preferred amphoteric or zwitterionic surfactant is an amidobetaine amphoteric surfactant of the general formula (III): or r2 Ri----C---NH(CH2)m---N---OH2OO2'R3 (III) where m is 2 or 3; R1C(O) is selected from linear or branched, saturated or unsaturated acyl groups having 8 to 22 carbon atoms and mixtures thereof; and R2 and R3 are each independently selected from alkyl, hydroxyalkyl, or carboxyalkyl groups having 1 to 6 carbon atoms and mixtures thereof. An example is cocamidopropyl betaine. The preferred level of such a surfactant is 0.5 to 10% by weight of the total composition, more preferably 2 to 8% by weight, with a maximum preference of 1 to 5% by weight. Another optional but preferred surfactant is an alkyl glycinate or alkyl carboxyglycinate. If present, it is present at a level of 1 to 8% by weight, preferably 2 to 6% by weight. Preferably, the alkyl glycinate and / or alkyl carboxyglycinate has a group 1418710 of 21 C8-22 carbon atoms, in the form of a salt with a solubilizing cation such as sodium, potassium, ammonium, or substituted ammonium. The preferred glycinates are sodium coco-glycinate and sodium cocoyl-glycinate. Mixtures of any of the amphoteric or zwitterionic surfactants listed above may also be suitable. Preferred mixtures are those of cocamidopropyl betaine with other amphoteric or zwitterionic surfactants as described above. An additional preferred amphoteric or zwitterionic surfactant is sodium cocoamphoacetate. In preferred embodiments, the cleaning step comprises an anionic alkyl sulfate and / or ethoxylated alkyl sulfate surfactant; and a betaine surfactant, preferably an alkyl amidopropyl betaine. The total amount of surfactants (including any co-surfactants) in a hair treatment composition is generally 1 to 50% by weight, preferably 2 to 40% by weight, more preferably 10 to 25% by weight of the total composition. Piroctone compound The piroctone compound for use in the present invention may include piroctone acid, primary, secondary, and tertiary olamine salts of piroctone acid (such as diethanolamine and triethanolamine salts), and mixtures thereof, preferably piroctone acid, primary olamine salt of piroctone acid (i.e., piroctone olamine, also known as Octopirox®), and mixtures thereof. The piroctone compound useful in the present invention normally contains the structure defined by formula (IV): 1418710 of 21 r5 where R4 is selected from C1-C17 hydrocarbon radicals, R5 is selected from C1-4 alkyl, C2-4 alkenyl or alkynyl, hydrogen, phenyl, or benzyl, and Mi is selected from hydrogen, monoethanolamine (MEA), diethanolamine (DEA), or triethanolamine (TEA). The preferred R4 group is (CH3)3CCH2CH(CH3)CH2- and R5 is a methyl group. More preferably, R3 is (CH3)3CCH2CH(CH3)CH2-, R5 is a methyl group, and Mi is a hydrogen or MEA group. Much more preferably, R4 is (CH3)3CCH2CH(CH3)CH2-, R5 is a methyl group, and Mi is a hydrogen group. Piroctone olamine is particularly preferred. The typical level of the piroctone compound is 0.01 to 5% by weight of the total composition, more preferably 0.05 to 2% by weight, much more preferably 0.1 to 1.5% by weight. Preferably, the weight ratio of homopolymer / copolymer to piroctone compound is preferably 2:1 or more preferably 1.5:1 or lower, with maximum preference from 0.3:1 to 1.1:1. Preferably, the piroctone compound makes up at least 50% by weight of the total level of anti-dandruff agent in the composition, more preferably at least 70% by weight. Oil-in-water emulsion 1418710 of 21 The compositions according to the invention may comprise an oil-in-water emulsion. The aqueous phase of the emulsion contains water. Suitablely, the emulsion comprises 25 to 85%, preferably 40 to 70%, and more preferably 45 to 60% water by weight of the total emulsion. Silicone is present in the oil-in-water emulsion. Silicone is a conditioning agent intended to be deposited on the hair and remain there after rinsing with water. The particle size of the silicone droplet (D3,2) within the water-in-oil emulsion is preferably from 10 nm to 10 microns, more preferably having a mean droplet diameter D3,2 of 50 nm to 5 microns, with a maximum preference of 100 nm to 5 microns. The mean droplet diameter D3,2 can be measured using a laser light diffraction technique, for example, with a Malvern Instruments 2600D Particle Sizer. The typical level of silicone is 0.1 to 5% by weight of the total composition, preferably 0.3 to 3% by weight, and more preferably 0.5 to 2.5% by weight. Typical silicones may include polyalkyl siloxanes, polyaryl siloxanes, polyalkylaryl siloxanes, polyethersiloxane copolymer, and mixtures thereof. The silicone may comprise a functionalized silicone. Suitable functionalized silicones include, for example, silicones substituted with hydroxyl, amino, carboxy, betaine, quaternary ammonium, carbohydrate, hydroxy, and alkoxy groups. The functionalized silicone may also contain multiple substitutions. Preferably, the functionalized silicone is an amino silicone, especially if the priroctone compound is to be solubilized in silicone. Amino silicones are described in EP455185 and include trimethylsilylamodimethicone 1418710 of 21 as shown below, and are sufficiently insoluble in water to be useful in the emulsion: Si (CH3)3-O-[Si(CH3)2-O-]x-[Si(CH3) (R6-NH-CH2CH2-NH2)-O-]y-Si(CH3)3 Where x + y is a number from approximately 50 to approximately 500, and the weight percent amine functionality is from approximately 0.03% to approximately 8%, and where R6 is an alkylene group having 2 to 5 carbon atoms. Preferably, the number x + y is from 100 to 300, and the weight percent amine functionality is from approximately 0.5% to 4%. As stated herein, the weight percent amine functionality is measured by titrating a sample of the amino silicone against alcoholic hydrochloric acid to the bromocresol green endpoint. The weight percent amine is calculated using a molecular weight of 45 (corresponding to CH3-CH2-NH2). Other cationic polymers include polygalactomannans and polysaccharide polymers, such as cationic cellulose derivatives and cationic starch derivatives. Suspension agent The suspending agent is a preferred feature of the composition. Suitable suspending agents are selected from polyacrylic acids, crosslinked polymers of acrylic acid, copolymers of acrylic acid with a hydrophobic monomer, copolymers of monomers containing carboxylic acid and acrylic esters, crosslinked copolymers of acrylic acid and acrylate esters, heteropolysaccharide gums, and long-chain crystalline acyl derivatives. The long-chain acyl derivative is desirablely selected from ethylene glycol stearate, fatty acid alkanolamides having 16 to 22 carbon atoms, and mixtures of 1418710 of 21. Ethylene glycol distearate and polyethylene glycol distearate 3 are preferred long-chain acyl derivatives because they impart pearlescence to the composition. Polyacrylic acid is commercially available as Carbopol 420, Carbopol 488, or Carbopol 493. Polymers of acrylic acid crosslinked with a polyfunctional agent may also be used; these are commercially available as Carbopol 910, Carbopol 934, Carbopol 941, and Carbopol 980. An example of a suitable copolymer of a monomer containing carboxylic acid and acrylic acid esters is Carbopol 1342. All Carbopol (registered trademark) materials are available from Goodrich. Suitable crosslinked polymers of acrylic acid and acrylate esters are Pemulen TR1 or Pemulen TR2. A suitable heteropolysaccharide gum is xanthan gum, for example, that available as Kelzan mu. Mixtures of any of the above suspending agents may be used. A mixture of crosslinked acrylic acid polymer and long-chain crystalline acyl derivative is preferred. One example that is the most preferred is a crosslinked polyacrylate polymer. The suspending agent, if included, will generally be present in the shampoo composition of the invention at levels of 0.01 to 5% by weight, preferably 0.1 to 2.5% by weight, more preferably 0.25 to 1% by weight. The viscosity of the composition ranges appropriately between 3,000 and 10,000 mPa.s, preferably between 4,000 and 8,000 mPa.s, more preferably between 5,000 and 7,000 mPa.s when measured using a Brookfield V2 viscometer (RTV5 spindle, 1 minute, 20 rpm) at 30 °C. The pH of the composition of the invention preferably ranges from 3 to 9, more preferably from 4 to 7, even more preferably from 4.5 to 6.5. 1418710 of 21 Other optional components The composition may optionally include one or more components for use in hair treatment products, compatible with the essential components described above, and which do not unduly impair the sensory properties, rheology of the formulation, and conditioning performance. The individual concentrations of these optional components may range from 0.001% to 10% by weight of the total composition, preferably from 0.01% to 5% by weight. Such components may include fragrances, dyes and pigments, pH adjusting agents, pearlizers or opacifiers, viscosity modifiers, preservatives, and natural hair nutrients such as botanicals, fruit extracts, sugar derivatives, and amino acids. The composition may also include an additional silicone that is not present in the oil-in-water emulsion phase.The additional silicone may be the same as or different from the silicone included in the emulsion phase. The composition may also include additional anti-dandruff and / or antimicrobial agents such as pyridine salts, pine tar, sulfur, salicylic acid, azoles, selenium sulfide, or mixtures thereof. How to use The composition is used to treat a surface. An effective amount of the composition is applied to a selected desired area of ​​hair and / or scalp, which has been moistened, preferably with water. The composition may be left on the surface for a specified time to take effect, preferably combined with massage, before rinsing with water. The specified time is preferably 20 seconds to 2 minutes, more preferably 30 seconds to 1 minute. The effective amount typically ranges from 1 g to 20 g, preferably from 2.5 g to 10 g. 1418710 of 21 The compositions of the invention are primarily intended for topical application to the scalp and / or at least a portion of an individual's hair, either in compositions that are left on or rinsed off, preferably in compositions that are rinsed off like shampoos. The following examples are provided to facilitate understanding of the present invention. The examples are not provided to limit the scope of the claims. Examples according to the invention are illustrated by a number, and comparative examples by a letter. Examples The following examples were prepared: 1418710 of 21 Table 1 Example 1 2 3 4 AB 5 6 7 8 CD Sodium laureth sulfate 1 EO 13 13 13 13 13 13 Sodium laureth sulfate 3EO 8 8 8 8 8 8 Cocamidopropyl betaine 1.5 1.5 1.5 1.5 1.5 1.5 4 4 4 4 4 Dimeticonol / TEA-dodecylbenceno sulfonate 2 2 2 2 2 2 2 2 2 2 2 2 N-DurHance A1000 (Acrylamidopropyltrimonium chloride polymer)** 0.2 0.5 0.2 0.5 N-DurHance AA2000 (Acrylamidopropyltrimonium chloride copolymer) Acrylamidopropyltrimonio / Acrilamida)** 0.2 0.5 0.2 0.5 Salcare SC60 (Copolímero de Cloruro de Acrilamidopropiltrimonio / Acrilamida)*** 0.2 0.5 0.2 0.5 Octopirox 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 Water and lesser ingredients Ha sta 10 0 Ha sta 10 0 Hast a 100 Ha sta 10 0 Ha sta 10 0 Ha sta 10 0 Ha sta 10 0 Ha sta 10 0 Ha sta 10 0 Ha sta 10 0 Ha sta 10 0 Ha sta 10 0 * molecular weight 200,000, charge density (meq / g) 4.8 ** molecular weight 300,000, charge density (meq / g) 4.8 1418710 of 21 molecular weight 1,000,000, load density (meq / g) 1.9 1418710 of 21 0.1 g of the Example composition per g of hair was applied uniformly to a hair strand. The hair strands were washed twice. After washing, the strands were placed in a drying chamber (50°C) until dry. Once dry, the strands were transferred to a flask containing 10 mL of ethanol. The flask was sealed and placed in a rotating bottle for a predetermined period. Using a syringe, an appropriately sized sample was drawn for analysis and filtered through a syringe filter into an analytical vial, using HPLC-UV methodologies, against a known set of standards containing known amounts of Octopirox in ethanol (pg / mL). 1418710 of 21 Table 2 - Octopirox Deposition Example 1 2 3 4 AB 5 6 7 8 CD Octopirox Deposition (ppm) 11.93 14.6 11.01 16.63 8.61 6.56 11.91 17.13 14.32 17.68 13.19 13.6 4 Standard Deviation 2.65 3.24 2.06 8.37 1.72 0.38 2.93 1.89 1.88 3.47 2.83 1.50 The examples of the invention deposit octopirox onto the hair more effectively than the comparative examples.

Claims

1. A cosmetic composition for hair care, excluding its therapeutic uses, characterized by: a) a piroctone compound selected from the group of compounds comprising piroctone acid, primary, secondary and tertiary olamine salts of piroctone acid, and compounds containing the structure defined by formula (IV): (FORMULA 1) wherein R4 is selected from C1-17 hydrocarbon radicals, R5 is selected from C1-4 alkyl, C2-4 alkenyl or alkynyl, hydrogen, phenyl or benzyl, and M1 is selected from hydrogen, monoethanolamine (MEA), diethanolamine (DEA), or triethanolamine (TEA); (yb) cationic homopolymer and / or copolymer comprising an acrylamide propyltrimonium moiety wherein the homopolymer and / or copolymer has a charge density of at least 3.5 meq / ga pH 7 and a weight-weight average molecular weight (g / mol) of 100,000 to 500.000 h (determined by SEC (Size Exclusion Chromatography) analysis using absolute calibration (universal calibration)). 11 Claims follow.