VETERINARY VIRUS-LIKE PARTICLE COMPOSITIONS MODIFIED FROM CMV AND IL-1β MUTEIN ANTIGENS

AR135403A1Pending Publication Date: 2026-09-02ELANCO US INC +1
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Patent Information

Application Number
ARP20250100602
Authority / Receiving Office
AR · AR
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-03-06
Filing Date
2025-03-05
Publication Date
2026-09-02
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Claims

The present invention relates to compositions comprising modified virus-like particles (VLPs) of cucumber mosaic virus (CMV), and in particular to modified CMV VLPs comprising chimeric CMV polypeptides comprising a stretch of consecutive negative amino acids selected from aspartic acid and / or glutamic acid to which specific interleukin-1β mutain antigens, IL-1β-D145X antigens, are attached, as well as to pharmaceutical compositions thereof, compositions preferably serving as vaccines to generate immune responses, in particular antibody responses, against IL-1β.