PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC AND HEPATIC DISORDERS
Patent Information
- Application Number
- ARP20250100669
- Authority / Receiving Office
- AR · AR
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-03-14
- Filing Date
- 2025-03-13
- Publication Date
- 2026-09-16
Claims
Oral compositions of small molecule GLP-1 receptor agonists and dual GIP / GLP-1 receptor agonists, and uses thereof.
1. A pharmaceutical composition, characterized in that it comprises: a therapeutically effective amount of Compound A or a pharmaceutically acceptable salt thereof; and a therapeutically effective amount of a dual GIP / GLP-1 agonist.
99. A pharmaceutical composition characterized in that it comprises: (i) a dual GIP / GLP-1 receptor agonist layer comprising: (a) sodium salcaprozate; and (b) a therapeutically effective amount of the compound having the structure of formula (1); and (ii) a TR-β agonist layer comprising: (a) polyvinylpyrrolidinone-vinyl acetate (PVP-VA) copolymer, (b) a therapeutically effective amount of Compound A; wherein Compound A and PVP-VA are combined to form a spray-drying dispersion.