ANTIBODY-DRUG CONJUGATES THAT BIND TO NaPi2b

AR135650A1Pending Publication Date: 2026-10-14MERCK PATENT GMBH
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Patent Information

Application Number
ARP20250100889
Authority / Receiving Office
AR · AR
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-04-04
Filing Date
2025-04-04
Publication Date
2026-10-14
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Claims

The present invention relates to ADCs that are joined to NaPi2b.

1. Antibody-drug conjugate (ADC), wherein the ADC is a compound of formula (1), wherein n is the number of [(linker) – (exatec)] fragments covalently bound to the antibody; and wherein n is preferably between 1 and 10 and more preferably around 4, and the antibody is bound to NaPi2b.

3. A pharmaceutical composition comprising the ADC of claim 1 or 2.