Anti-CD79 antibodies and their uses

Abstract

Abstract The present disclosure provides humanized and affinity matured antibodies (mAbs) and fragments thereof that specifically bind to CD79 with high affinity. The anti-CD79 mAbs and fragments thereof can be used to treat antibody-associated conditions, including autoimmune diseases, allergies, transplant rejection, or immune-mediated rejection of a 5 therapeutics optionally in combination with an additional therapeutic agent. Furthermore, the anti-CD79 mAbs and fragments thereof can be used for diagnostic purposes, including to detect CD79 cells in biological samples and to diagnose B-cell associated disorders. Abstract 20 26 20 41 53 28 M ay 2 02 6 A b s t r a c t 2 0 2 6 2 0 4 1 5 3 2 8 M a y 2 0 2 6 5

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