Systems, devices, and methods for wireless monitoring

Abstract

OFFICIAL OFFICIAL Described here are wireless monitoring devices, systems, and methods for monitoring one or more physiological parameters of a patient. These devices and systems may, for example, receive a signal waveform transmitted through one or more of a fluid and a physiological structure of a patient. This signal waveform may be processed to generate a set of waveform features, or waveform parameter data, used to estimate a physiological parameter such as blood velocity, heart wall thickness, and the like. The devices described herein may have low energy requirements as well as a compact and implantable form that may allow for continuous or semi- continuous monitoring of the patient. For example, one or more wireless monitors may be disposed on an expandable cardiac implant such as a prosthetic valve or a stent, and may be used to monitor one or more of blood velocity, blood pressure, operation of the prosthetic valve or stent, and the like, over time. OFFICIAL OFFICIAL WO 2020 / 210490 PCT / US2020 / 027468 1 / 13 100 External Wireless Device 114 Transducer Processor 130 120 142 142 140 140 Wireless Monitor 110 Wireless Monitor 112 144 Power Transducer Transducer Power Circuit 150 120 120 Circuit 150 146 Processor 130 Processor 130 FIG. 1 200 Wireless Monitor 210 244 Transducer Transducer 220 222 246 Processor 230 FIG. 2 20 26 20 52 67 03 J ul 2 02 6 W O 2 0 2 0 / 2 1 0 4 9 0 P C T / U S 2 0 2 0 / 0 2 7 4 6 8 1 / 1 3 2 0 2 6 2 0 5 2 6 7 0 3 J u l 2 0 2 6 1 0 0 E x t e r n a l W i r e l e s s D e v i c e 1 1 4 T r a n s d u c e r P r o c e s s o r 1 3 0 1 2 0 1 4 2 1 4 2 W i r e l e s s M o n i t o r 1 1 2 P o w e r T r a n s d u c e r T r a n s d u c e r P o w e r 1 2 0 1 4 6 P r o c e s s o r 1 3 0 P r o c e s s o r 1 3 0 F I G . 1 2 0 0 W i r e l e s s M o n i t o r 2 1 0 2 4 4 T r a n s d u c e r T r a n s d u c e r 2 2 0 2 2 2 2 4 6 P r o c e s s o r 2 3 0 F I G . 2

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