Electrotransfer Therapeutic Delivery Device, System and Method

Abstract

41 23563956_2 Abstract Disclosed herein is a device capable of high efficiency DNA electrotransfer into cells via a single capacitive discharge. The principle of this system relates to the storage of a quantum of charge on a capacitor which is then discharged through an electrode array configured to produce an electric field having electric field potential gradients focussed 5 through a region by the array configuration and of sufficient in strength for efficient electrotransfer of DNA into cells. This DNA, or related ribonucleic acid molecules or indeed other charged molecules, upon entering the cells, can affect changes in biological function. 10 41 10 20 26 20 61 86 16 J ul 2 02 6 4 1 2 0 2 6 2 0 6 1 8 6 1 6 J u l 2 0 2 6 1 0

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